Search Results - "Ozcan, Aysen Gunel"

Global miRNA expression of bone marrow mesenchymal stem/stromal cells derived from Fanconi anemia patients by Cagnan, Ilgin, Keles, Mustafa, Keskus, Ayse Gokce, Tombaz, Melike, Sahan, Ozge Burcu, Aerts-Kaya, Fatima, Uckan-Cetinkaya, Duygu, Konu, Ozlen, Gunel-Ozcan, Aysen

“…Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects, and bone marrow (BM) failure. Hematopoietic stem…”
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Stem Cells under Stress by Gunel-Ozcan, Aysen

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From Stem Cell Biology to The Treatment of Lung Diseases by Esendagli, Dorina, Gunel-Ozcan, Aysen

“…The exposure of lung to noxious agents or gasses leads to injury, which further enhances repair mechanisms by promoting the proliferation and differentiation…”
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Tenascin-R: Role in the central nervous system by Anlar, Banu, Gunel-Ozcan, Ayşen

“…Tenascin-R (TN-R), a member of the tenascin family of extracellular matrix glycoproteins, is exclusive to the nervous system. It affects cell migration,…”
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HFE H63D mutation frequency shows an increase in Turkish women with breast cancer by Gunel-Ozcan, Aysen, Alyilmaz-Bekmez, Sibel, Guler, Emine Nilufer, Guc, Dicle

“…The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously…”
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spectrum of FMF mutations and genotypes in the referrals to molecular genetic laboratory at Kırıkkale University in Turkey by Gunel-Ozcan, Aysen, Sayın, Derya Beyza, Mısırlıoğlu, Emine Dibek, Güliter, Sefa, Yakaryilmaz, Fahri, Ensari, Cuneyt

“…Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder characterised by recurrent and self-limited abdominal pain, synovitis and…”
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Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene by Esendagli, Gunes, Canpinar, Hande, Yilmaz, Guldal, Gunel-Ozcan, Aysen, Oguz Guc, M., Kansu, Emin, Guc, Dicle

“…The presence of CD40 on carcinoma cells is an important factor for the generation of tumor-specific responses induced by CD40 ligation. In an…”
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Dual Effect of Glucocorticoid-Induced Tumor Necrosis Factor–Related Receptor Ligand Carrying Mesenchymal Stromal Cells on Small Cell Lung Cancer: A Preliminary in vitro Study by Kopru, Cagla Zubeyde, Cagnan, Ilgin, Akar, Irem, Esendagli, Gunes, Korkusuz, Petek, Gunel-Ozcan, Aysen

“…Abstract Background aims TNFR family member glucocorticoid-induced tumor necrosis factor–related receptor (GITR/TNFRSF18) activation by its ligand…”
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miRNA Expression Profiling in Mesenchymal Stromal/Stem Cells Derived from G-CSF Primed Bone Marrows by Gunel-Ozcan, Aysen, Cagnan, Ilgin, Kansu, Emin, Uckan, Duygu

“…Regulatory microRNAs (miRNAs) are involved in the molecular control of hematopoiesis and diseases that result from aberrations during this process. Bone marrow…”
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The frequency of Familial Mediterranean fever gene mutations and genotypes at Kirikkale and comparison with the mean of regional MEFV mutation frequency of Turkey by Sayın Kocakap, Derya Beyza, Günel-Özcan, Ayşen, Çabuk, Feryal, Ensari, Cüneyt

“…In this study we have retrospectively analysed the mutation spectrum of the 351 Familial Mediterranean fever patients referred to Kırıkkale University Faculty…”
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PKNOX2 expression and regulation in the bone marrow mesenchymal stem cells of Fanconi anemia patients and healthy donors by Cagnan, Ilgin, Cosgun, Erdal, Konu, Ozlen, Uckan, Duygu, Gunel-Ozcan, Aysen

“…HOX and TALE transcription factors are important regulators of development and homeostasis in determining cellular identity. Deregulation of this process may…”
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TGF-β1 Production By Bone Marrow Mesenchymal Stem Cells of FANCD2 Differs from Other Fanconi Anemia Complementation Groups by Cagnan, Ilgın, Gunel-Ozcan, Aysen, Aerts-Kaya, Fatima, Ameziane, Najim, Kuskonmaz, Baris, Dorsman, Josephine, Gumruk, Fatma, Cetinkaya, Duygu

“…TGF-β secretion from cells in the bone marrow (BM) niche affects hematopoietic stem cell (HSC) fate and has a cardinal role in HSC quiescence. As a component…”
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Bone Marrow Mesenchymal Stem Cells Carrying FANCD2 Mutation Differ from the Other Fanconi Anemia Complementation Groups in Terms of TGF-β1 Production by Cagnan, Ilgin, Gunel-Ozcan, Aysen, Aerts-Kaya, Fatima, Ameziane, Najim, Kuskonmaz, Baris, Dorsman, Josephine, Gumruk, Fatma, Uckan, Duygu

“…Transforming growth factor beta (TGF-β) secretion from cells in the bone marrow (BM) niche affects hematopoietic stem cell (HSC) fate and has a cardinal role…”
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Differential miRNA expression profile of bone marrow derived mesenchymal stem cells in fanconi anemia patients and healthy donors by Gunel-Ozcan, Aysen, Cagnan, Ilgin, Konu, Ozlen, Kaya, Fatima Aerts, Kuskonmaz, Baris, Uckan, Duygu

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Relative gene expression analysis shows increased mRNA levels of HoxB7 and HoxA10 and decreased mRNA levels of Pbx1 in the bone marrow derived mesenchymal progenitors from Fanconi anemia patients by Ozcan, Aysen Gunel, Cagnan, Ilgin, Kuskonmaz, Baris, Cetinkaya, Duygu Uckan

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Molecular and functional analysis of a novel recombinant clone of rat (Rattus norvegicus) CD40 ligand (CD40L) gene by Esendagli, Gunes, Gunel-Ozcan, Aysen, Canpinar, Hande, Guc, Dicle

“…Genetic material obtained from various individuals may contain certain polymorphisms which may conflict with the predetermined DNA sequence and consequently,…”
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Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility by Gunel-Ozcan, Aysen, Basar, M. Murad, Kısa, Ucler, Ankaralı, Handan C

“…The aim of this study was to screen infertile men for HFE H63D mutation in correlation with clinical characteristics of infertile men (sperm concentration,…”
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Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells by Güney-Esken, Gülen, Erol, Özgür Doğuş, Pervin, Burcu, Gürhan Sevinç, Gülben, Önder, Tamer, Bilgiç, Elif, Korkusuz, Petek, Günel-Özcan, Ayşen, Uçkan-Çetinkaya, Duygu, Aerts-Kaya, Fatima

“…Griscelli syndrome type 2 (GS-2) is a rare, autosomal recessive immune deficiency syndrome caused by a mutation in the RAB27A gene, which results in the…”
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PKNOX2 regulated by TGFbeta is a new candidate to explain bone marrow failure in fanconi anemia by Cagnan, Ilgın, Kaya, Fatima Aerts, Cosgun, Erdal, Konu, Özlen, Uckan-Cetinkaya, Duygu, Gunel-Ozcan, Ayşen

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Development and characterization of iPS cell lines from a patient with Griscelli type 2 disease by Güney, Gülen, Pervin, Burcu, Sahan, Özge Burcu, Uckan-Cetinkaya, Duygu, Günel-Özcan, Ayşen, Schambach, Axel, Aerts-Kaya, Fatima

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