Search Results - "Ozawa, Kentaro"

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages by Nakajima, Akira, Nakatani, Akiho, Hasegawa, Sae, Irie, Junichiro, Ozawa, Kentaro, Tsujimoto, Gozoh, Suganami, Takayoshi, Itoh, Hiroshi, Kimura, Ikuo

“…The regulation of inflammatory responses within adipose tissue by various types of immune cells is closely related to tissue homeostasis and progression of…”
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DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria by Ozawa, Kentaro, Tsumoto, Hiroki, Miura, Yuri, Yamaguchi, Junji, Iguchi-Ariga, Sanae M. M., Sakuma, Tetsushi, Yamamoto, Takashi, Uchiyama, Yasuo

“…The DJ-1 gene, a causative gene for familial Parkinson’s disease (PD), has been reported to have various functions, including transcriptional regulation,…”
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Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways by Nagayama, Kosuke, Kyotani, Yoji, Zhao, Jing, Ito, Satoyasu, Ozawa, Kentaro, Bolstad, Francesco A, Yoshizumi, Masanori

“…Angiotensin II (Ang II) is a main pathophysiological culprit peptide for hypertension and atherosclerosis by causing vascular smooth muscle cell (VSMC)…”
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Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation by Inoue, Daisuke, Kimura, Ikuo, Wakabayashi, Masaki, Tsumoto, Hiroki, Ozawa, Kentaro, Hara, Takafumi, Takei, Yoshinori, Hirasawa, Akira, Ishihama, Yasushi, Tsujimoto, Gozoh

“…► SCFAs increase NE release from primary-cultured sympathetic neurons via GPR41. ► Sympathetic activation by SCFA involves Gβγ, PLCβ3, ERK1/2, and synapsin 2…”
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Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch by Zhao, Jing, Nishimura, Yuhei, Kimura, Akihiko, Ozawa, Kentaro, Kondo, Toshikazu, Tanaka, Toshio, Yoshizumi, Masanori

“…The pulsatile nature of blood flow exposes vascular smooth muscle cells (VSMCs) in the vessel wall to cyclic mechanical stretch (CMS), which evokes VSMC…”
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Involvement of Endoplasmic Reticulum Stress in Insulin Resistance and Diabetes by Nakatani, Yoshihisa, Kaneto, Hideaki, Kawamori, Dan, Yoshiuchi, Kazutomi, Hatazaki, Masahiro, Matsuoka, Taka-aki, Ozawa, Kentaro, Ogawa, Satoshi, Hori, Masatsugu, Yamasaki, Yoshimitsu, Matsuhisa, Munehide

“…Type 2 diabetes is one of the most prevalent and serious metabolic diseases in the world, and insulin resistance and pancreatic β-cell dysfunction are the…”
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Long‐term analysis of adalimumab in Japanese patients with moderate to severe hidradenitis suppurativa: Open‐label phase 3 results by Morita, Akimichi, Takahashi, Hidetoshi, Ozawa, Kentaro, Imafuku, Shinichi, Takekuni, Nakama, Takahashi, Kenzo, Matsuyama, Takashi, Okubo, Yukari, Zhao, Yiwei, Kitamura, Susumu, Takei, Keiko, Yokoyama, Masayuki, Hayashi, Nobukazu, Terui, Tadashi

“…This phase 3, multicenter, open‐label single‐arm study evaluated adalimumab (ADA) in Japanese patients with moderate to severe hidradenitis suppurativa (HS)…”
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Adjuvant therapy with nivolumab versus ipilimumab after complete resection of stage III/IV melanoma: Japanese subgroup analysis from the phase 3 CheckMate 238 study by Yokota, Kenji, Uchi, Hiroshi, Uhara, Hisashi, Yoshikawa, Shusuke, Takenouchi, Tatsuya, Inozume, Takashi, Ozawa, Kentaro, Ihn, Hironobu, Fujisawa, Yasuhiro, Qureshi, Anila, Pril, Veerle, Otsuka, Yasushi, Weber, Jeffrey, Yamazaki, Naoya

“…The multinational phase 3 CheckMate 238 trial compared adjuvant therapy with nivolumab versus ipilimumab among patients with resected stage III or IV melanoma…”
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Twenty‐four‐week interim analysis from a phase 3 open‐label trial of adalimumab in Japanese patients with moderate to severe hidradenitis suppurativa by Morita, Akimichi, Takahashi, Hidetoshi, Ozawa, Kentaro, Imafuku, Shinichi, Nakama, Takekuni, Takahashi, Kenzo, Matsuyama, Takashi, Okubo, Yukari, Kitamura, Susumu, Matsuda, Naoto, Zhao, Yiwei, Yokoyama, Masayuki, Hayashi, Nobukazu, Terui, Tadashi

“…Hidradenitis suppurativa (HS) is a chronic skin disease characterized by recurrent painful inflamed nodules/abscesses and draining fistulas that negatively…”
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Olmesartan inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch through the inhibition of the c-Jun N-terminal kinase and p38 signaling pathways by Ito, Satoyasu, Ozawa, Kentaro, Zhao, Jing, Kyotani, Yoji, Nagayama, Kosuke, Yoshizumi, Masanori

“…Acute aortic dissection (AAD) is a life-threating disease; however, there is almost no effective pharmacotherapy for it. An increase in c-Jun N-terminal kinase…”
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Observational study of skin and soft-tissue Staphylococcus aureus infection in patients infected with HIV-1 and epidemics of Panton–Valentine leucocidin-positive community-acquired MRSA infection in Osaka, Japan by Hirota, Kazuyuki, Watanabe, Dai, Koizumi, Yusuke, Sakanashi, Daisuke, Ueji, Takashi, Nishida, Yasuharu, Takeda, Mami, Taguri, Takahiro, Ozawa, Kentaro, Mikamo, Hiroshige, Shirasaka, Takuma, Uehira, Tomoko

“…In patients infected with human immunodeficiency virus (HIV)-1 at our hospital, we observed increases in skin and soft-tissue infections (SSTIs) by…”
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The Role of Big Mitogen-Activated Protein Kinase 1 (BMK1) / Extracellular Signal-Regulated Kinase 5 (ERK5) in the Pathogenesis and Progression of Atherosclerosis by Yoshizumi, Masanori, Kyotani, Yoji, Zhao, Jing, Nagayama, Kosuke, Ito, Satoyasu, Tsuji, Yuichi, Ozawa, Kentaro

“…Big mitogen-activated protein kinase 1 (BMK1), also known as extracellular signal-regulated kinase 5 (ERK5), is a newly identified member of the…”
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Nitric Oxide Regulates Endocytosis by S-Nitrosylation of Dynamin by Wang, Gaofeng, Moniri, Nader H., Ozawa, Kentaro, Stamler, Jonathan S., Daaka, Yehia

“…The GTPase dynamin regulates endocytic vesicle budding from the plasma membrane, but the molecular mechanisms involved remain incompletely understood. We…”
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Neutrophil-rich Variant of Persistent Bullous Grover's Disease by Togo, Sayaka, Ozawa, Kentaro, Fujii, Asami, Tanii, Tsukasa, Tsuruta, Daisuke, Ishii, Norito, Hashimoto, Takashi, Tadokoro, Taketsugu, Isei, Taiki

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The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes by OZAWA, Kentaro, MIYAZAKI, Mayuki, HORI, Osamu, YAMASAKI, Yoshimitsu, OGAWA, Satoshi, MATSUHISA, Munehide, TAKANO, Katsura, NAKATANI, Yoshihisa, HATAZAKI, Masahiro, TAMATANI, Takashi, YAMAGATA, Kazuya, MIYAGAWA, Jun-Ichiro, KITAO, Yasuko

“…The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes Kentaro Ozawa 1 , Mayuki Miyazaki 1 2 , Munehide Matsuhisa 3 , Katsura…”
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Millimeter-sized belt-like pattern formation of actin filaments in solution by interacting with surface myosin in vitro by Ozawa, Kentaro, Taomori, Hirotaka, Hoshida, Masayuki, Kunita, Ituki, Sakurazawa, Sigeru, Honda, Hajime

“…The movements of single actin filaments along a myosin-fixed glass surface were observed under a conventional fluorescence microscope. Although random at a low…”
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Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation by Kitao, Yasuko, Imai, Yuzuru, Ozawa, Kentaro, Kataoka, Ayane, Ikeda, Toshio, Soda, Mariko, Nakimawa, Kazuhiko, Kiyama, Hiroshi, Stern, David M., Hori, Osamu, Wakamatsu, Kazumasa, Ito, Shosuke, Itohara, Shigeyoshi, Takahashi, Ryosuke, Ogawa, Satoshi

“…Selective loss of dopaminergic neurons is the final common pathway in Parkinson's disease. Expression of Parkin associated endothelin-receptor like receptor…”
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Azelnidipine inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch by Zhao, Jing, Ozawa, Kentaro, Kyotani, Yoji, Nagayama, Kosuke, Ito, Satoyasu, Komatsubara, Akira T, Tsuji, Yuichi, Yoshizumi, Masanori

“…Acute aortic dissection is the most common life-threatening vascular disease, with sudden onset of severe pain and a high fatality rate. Clarifying the…”
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Detection of Nitric Oxide Induced by Angiotensin II Receptor Type 1 Using Soluble Guanylate Cyclase beta1 Subunit Fused to a Yellow Fluorescent Protein, Venus by Tsuji, Yuichi, Ozawa, Kentaro, Komatsubara, Akira T., Zhao, Jing, Nishi, Mayumi, Yoshizumi, Masanori

“…Nitric oxide (NO) is an important gaseous molecule involved in many physiological and pathophysiological processes, including the regulation of G…”
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Regulation of seven-transmembrane receptor (GPCR) by nitric oxide by Ozawa, Kentaro

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