Search Results - "Ozawa, Junichi"

Impact of being large-for-gestational-age on neonatal mortality and morbidities in extremely premature infants by Ozawa, Junichi, Tanaka, Kosuke, Kabe, Kazuhiko, Namba, Fumihiko

“…Background Small for gestational age (SGA) infants have an increased risk for neonatal mortality and morbidities. However, few studies have examined the risk…”
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Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1　― Modified Schwartz Score by Ozawa, Junichi, Ohno, Seiko, Fujii, Yusuke, Makiyama, Takeru, Suzuki, Hiroshi, Saitoh, Akihiko, Horie, Minoru

“…Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been often misdiagnosed as long QT syndrome (LQTS) type 1 (LQT1), which…”
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An NGS-based genotyping in LQTS; minor genes are no longer minor by Ohno, Seiko, Ozawa, Junichi, Fukuyama, Megumi, Makiyama, Takeru, Horie, Minoru

“…Mutations in KCNQ1, KCNH2, and SCN5A are the major cause of long QT syndrome (LQTS). More than 90% of the genotyped patients have been reported to carry…”
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Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation by Arai, Yukio, Ito, Masato, Tanaka, Kosuke, Ozawa, Junichi, Motojima, Yukiko, Matsuoka, Kikumi, Igarashi, Kazuhiko, Namba, Fumihiko

“…Background Intrauterine inflammation affects fetal lung development. BTB and CNC homology 1 (Bach1) is a transcriptional repressor of heme oxygenase-1 ( HO-1 )…”
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Dynamic QT Changes in Long QT Syndrome Type 8 by Harada, Mizuki, Suzuki, Hiroshi, Ohno, Seiko, Ozawa, Junichi, Saitoh, Akihiko, Horie, Minoru

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High Prevalence of Late-Appearing T-Wave in Patients With Long QT Syndrome Type 8 by Fukuyama, Megumi, Ohno, Seiko, Ozawa, Junichi, Kato, Koichi, Makiyama, Takeru, Nakagawa, Yoshihisa, Horie, Minoru

“…Background:Long QT syndrome type 8 (LQT8) is a rare genotype of long QT syndrome. Late-appearing T-waves (LaT) are often documented in patients with LQT8, as…”
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Therapeutic response of iNO in preterm infants with hypoxemic respiratory failure by Oka, Shuntaro, Nishimura, Eri, Ozawa, Junichi, Haga, Mitsuhiro, Miyahara, Naoyuki, Sakatani, Shun, Minamitani, Yohei, Namba, Fumihiko

“…Background Inhaled nitric oxide (iNO) has been used as a rescue treatment for preterm infants with hypoxemic respiratory failure (HRF). However, its…”
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Increased CaV1.2 late current by a CACNA1C p.R412M variant causes an atypical Timothy syndrome without syndactyly by Ozawa, Junichi, Ohno, Seiko, Melgari, Dario, Wang, Qi, Fukuyama, Megumi, Toyoda, Futoshi, Makiyama, Takeru, Yoshinaga, Masao, Suzuki, Hiroshi, Saitoh, Akihiko, Ai, Tomohiko, Horie, Minoru

“…Timothy syndrome (TS) is a rare pleiotropic disorder associated with long QT syndrome, syndactyly, dysmorphic features, and neurological symptoms. Several…”
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Difference in pyruvic acid metabolism between neonatal and adult mouse lungs exposed to hyperoxia by Tanaka, Kosuke, Watanabe, Takaaki, Ozawa, Junichi, Ito, Masato, Nagano, Nobuhiko, Arai, Yukio, Miyake, Fuyu, Matsumura, Shun, Kobayashi, Shingo, Itakura, Ryuta, Namba, Fumihiko

“…Objective Neonatal lungs are more tolerant to hyperoxic injury than are adult lungs. This study investigated differences in the response to hyperoxic exposure…”
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Copy number variations of SCN5A in Brugada syndrome by Sonoda, Keiko, Ohno, Seiko, Ozawa, Junichi, Hayano, Mamoru, Hattori, Tetsuhisa, Kobori, Atsushi, Yahata, Mitsuhiko, Aburadani, Isao, Watanabe, Seiichi, Matsumoto, Yuichi, Makiyama, Takeru, Horie, Minoru

“…Loss-of-function mutations in SCN5A are associated in ∼20% of Brugada syndrome (BrS) patients. Copy number variations (CNVs) have been shown to be associated…”
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School-based routine screenings of electrocardiograms for the diagnosis of long QT syndrome by Fukuyama, Megumi, Horie, Minoru, Aoki, Hisaaki, Ozawa, Junichi, Kato, Koichi, Sawayama, Yuichi, Tanaka-Mizuno, Sachiko, Makiyama, Takeru, Yoshinaga, Masao, Nakagawa, Yoshihisa, Ohno, Seiko

“…School-based routine screenings of electrocardiograms (ECGs) have been performed upon admission to primary school (PS), junior high school (JHS), and high…”
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A severe case of cardiospondylocarpofacial syndrome with a novel MAP3K7 variant by Nyuzuki, Hiromi, Ozawa, Junichi, Nagasaki, Keisuke, Nishio, Yosuke, Ogi, Tomoo, Tohyama, Jun, Ikeuchi, Takeshi

“…Cardiospondylocarpofacial syndrome (CSCFS) is a congenital malformation characterized by growth retardation, facial features, short toes with carpal and tarsal…”
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Novel electrocardiographic criteria for short QT syndrome in children and adolescents by Suzuki, Hiroshi, Horie, Minoru, Ozawa, Junichi, Sumitomo, Naokata, Ohno, Seiko, Hoshino, Kenji, Ehara, Eiji, Takahashi, Kazuhiro, Maeda, Yoshichika, Yoshinaga, Masao, Tateno, Shigeru, Takagi, Junichi, Doi, Shozaburo, Hoshina, Satoshi, Sato, Isamu, Ishikawa, Taisuke, Makita, Naomasa, Chinushi, Masaomi, Akazawa, Kohei, Nagashima, Masami

“…Abstract Aims Although shortening of the corrected QT interval (QTc) is a key finding in the diagnosis of short QT syndrome (SQTS), there may be overlap of the…”
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Efficacy of cEEG and hepatic function to diagnose early acute encephalopathy by Sakurai, Yoshio, Osada, Kohei, Sakamoto, Wataru, Uchida, Yuta, Kawano, Akiko, Kobayashi, Shingo, Chikaishi, Maki, Kojima, Hideo, Ozawa, Junichi, Sakai, Hirokazu, Moriwaki, Koichi, Yamanouchi, Hideo

“…Background Early treatment may improve the prognosis of acute encephalopathy (AE). However, methods for early diagnosis have not yet been established. In this…”
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Preterm Infant with Generalized Arterial Calcification of Infancy Who Survived Due to Early Diagnosis and Appropriate Treatment with Bisphosphonates: A Case Report by Tanaka, Masato, Kobayashi, Akira, Kuwabara, Haruhiro, Nirei, Jun, Ozawa, Junichi, Sawano, Kentaro, Shibata, Nao, Nagasaki, Keisuke, Saitoh, Akihiko

“…Generalized arterial calcification of infancy (GACI) is a rare disease characterized by arterial calcification. GACI is caused by a mutation in the ENPP1 or…”
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Cytomegalovirus‐related sepsis‐like syndrome in very premature infants in Japan by Namba, Fumihiko, Nakagawa, Ryota, Haga, Mitsuhiro, Yoshimoto, Seiji, Tomobe, Yutaro, Okazaki, Kaoru, Nakamura, Kenji, Seki, Yoshiko, Kitamura, Souya, Shimokaze, Tomoyuki, Ikegami, Hitoshi, Nishida, Kosuke, Mori, Shigehiro, Tamai, Kei, Ozawa, Junichi, Tanaka, Kosuke, Miyahara, Naoyuki

“…Background Very premature infants are at high risk of developing a symptomatic postnatal cytomegalovirus (CMV) disease, such as CMV‐related sepsis‐like…”
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Phenotypic Variability of ANK2 Mutations in Patients With Inherited Primary Arrhythmia Syndromes by Ichikawa, Mari, Aiba, Takeshi, Ohno, Seiko, Shigemizu, Daichi, Ozawa, Junichi, Sonoda, Keiko, Fukuyama, Megumi, Itoh, Hideki, Miyamoto, Yoshihiro, Tsunoda, Tatsuhiko, Makiyama, Takeru, Tanaka, Toshihiro, Shimizu, Wataru, Horie, Minoru

“…Background:Mutations inANK2have been reported to cause various arrhythmia phenotypes. The prevalence ofANK2mutation carriers in inherited primary arrhythmia…”
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Pediatric Cohort With Long QT Syndrome　– KCNH2 Mutation Carriers Present Late Onset But Severe Symptoms by Ozawa, Junichi, Ohno, Seiko, Hisamatsu, Takashi, Itoh, Hideki, Makiyama, Takeru, Suzuki, Hiroshi, Saitoh, Akihiko, Horie, Minoru

“…Background:In children with long QT syndrome (LQTS), risk factors for cardiac events have been reported, but age-, gender- and genotype-related differences in…”
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Thioredoxin-1 Ameliorates Oxygen-Induced Retinopathy in Newborn Mice through Modulation of Proinflammatory and Angiogenic Factors by Ozawa, Junichi, Tanaka, Kosuke, Arai, Yukio, Haga, Mitsuhiro, Miyahara, Naoyuki, Miyamoto, Ai, Nishimura, Eri, Namba, Fumihiko

“…Oxygen-induced retinopathy (OIR) is an animal model for retinopathy of prematurity, which is a leading cause of blindness in children. Thioredoxin-1 (TRX) is a…”
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Contribution of a KCNH2 variant in genotyped long QT syndrome: Romano–Ward syndrome under double mutations and acquired long QT syndrome under heterozygote by Fujii, Yusuke, MD, Matsumoto, Yuichi, MD, Hayashi, Kenshi, MD, PhD, FJCC, Ding, Wei-Guang, MD, PhD, Tomita, Yukinori, MD, Fukumoto, Daisuke, MD, Wada, Yuko, MD, Ichikawa, Mari, MD, Sonoda, Keiko, MD, Ozawa, Junichi, MD, Makiyama, Takeru, MD, PhD, Ohno, Seiko, MD, PhD, Yamagishi, Masakazu, MD, PhD, FJCC, Matsuura, Hiroshi, MD, PhD, Horie, Minoru, MD, PhD, Itoh, Hideki, MD, PhD, FJCC

“…Abstract Background Long QT syndrome (LQTS) presents two clinical phenotypes, congenital and acquired forms. This study aims to evaluate the genetic…”
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