Search Results - "Oz, Umut Can"
-
1
Design of Polymeric Nanoparticles for Theranostic Delivery of Capsaicin as Anti‐Cancer Drug and Fluorescent Nitrogen‐Doped Graphene Quantum Dots
Published in Macromolecular bioscience (01-09-2024)“…In recent years, multifunctional nanocarriers that provide simultaneous drug delivery and imaging have attracted enormous attention, especially in cancer…”
Get full text
Journal Article -
2
Investigation on formulation parameters of donepezil HCl loaded solid lipid nanoparticles
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2023)“…Donepezil-HCl is a member of the acetylcholinesterase inhibitors that is indicated for the symptomatic treatment of Alzheimer’s disease (AD) and has many side…”
Get full text
Journal Article -
3
Guided bone regeneration by the development of alendronate sodium loaded in-situ gel and membrane formulations
Published in European journal of pharmaceutical sciences (01-12-2020)“…Biocompatible materials applied in guided bone regeneration are needed to prevent leakage caused by the invasion of peripheral epithelium. The aim of this…”
Get full text
Journal Article -
4
The Utilization of Poly(2‐ethyl‐2‐oxazoline)‐b‐Poly(ε‐caprolactone) Ellipsoidal Particles for Intracellular BIKDDA Delivery to Prostate Cancer
Published in Macromolecular bioscience (01-02-2021)“…Prostate cancer is the most common cancer, which is about 15–20% among male cancers worldwide. As most common strategies such as radiotherapy, chemotherapy, or…”
Get full text
Journal Article -
5
Formulation and Optimization of Nonionic Surfactants Emulsified Nimesulide-Loaded PLGA-Based Nanoparticles by Design of Experiments
Published in AAPS PharmSciTech (01-02-2014)“…This investigation aimed to develop nimesulide (NMS)-loaded poly(lactic-co-glycolic acid) (PLGA)-based nanoparticulate formulations as a biodegradable…”
Get full text
Journal Article -
6
Development and Optimization of Alendronate Sodium Loaded PLGA Nanoparticles by Central Composite Design
Published in Macromolecular research (01-09-2019)“…Alendronate sodium (AS) which supresses the activity of osteoclastic cells and leads to the inhibition of bone resorption, is one of the most clinically…”
Get full text
Journal Article -
7
In Situ Hydrogel Formulation for Intra-Articular Application of Diclofenac Sodium-Loaded Polymeric Nanoparticles
Published in Turkish journal of pharmaceutical sciences (01-04-2017)“…The world's population is getting older and the number of people suffering from arthritis is a major problem according to World Health Organization's data. In…”
Get full text
Journal Article -
8
Prostate cancer cell-specific BikDDA delivery by targeted polymersomes
Published in Applied nanoscience (01-09-2020)“…In this paper, we report the polymersome-mediated intracellular delivery of pro-apoptotic BikDDA gene using two different peptide–copolymer covalent…”
Get full text
Journal Article -
9
Correction to: Prostate cancer cell-specific BikDDA delivery by targeted polymersomes
Published in Applied nanoscience (2020)“…Unfortunately, the Fig. 6 was published incorrectly in the online published article…”
Get full text
Journal Article -
10
Central Composite Design for Optimization of Zoledronic Acid Loaded PLGA Nanoparticles
Published in Journal of pharmaceutical innovation (01-03-2020)“…Purpose Zoledronic acid (ZA) is one of the drugs used clinically for the treatment of osteoporosis, and its therapeutic effect is due to the inhibition of…”
Get full text
Journal Article -
11
PRO-DRUG NANOPARTICLES AS SYNERGISTIC DRUG COMBINATION CARRIERS FOR IDH1-WT GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (16-09-2023)“…Abstract AIMS Synergistic combinations of doxorubicin and gemcitabine have been assessed for post-surgical treatment of IDH1 wild-type glioblastoma (GBM). As a…”
Get full text
Journal Article -
12
-
13
Responsive Nanomaterial Delivery Systems for Pancreatic Cancer Management
Published in Advanced therapeutics (01-03-2024)“…Abstract Pancreatic cancer is characterized by a high mortality rate and unfavorable prognosis. This is primarily attributed to poor accumulation of…”
Get full text
Journal Article -
14
Development of reconstitutable suspensions containing diclofenac sodium-loaded microspheres for pediatric delivery
Published in Journal of microencapsulation (19-05-2015)“…Effective clinical utilisation of non-steroidal anti-inflammatory drugs, such as diclofenac sodium (DS) is significantly limited by their ulcerogenic potential…”
Get full text
Journal Article -
15
Design of Colloidally Stable and Non‐Toxic Petox‐Based Polymersomes for Cargo Molecule Encapsulation
Published in ChemNanoMat : chemistry of nanomaterials for energy, biology and more (01-06-2019)“…Polymersomes are vesicular constructs formed by the self‐assembly of polymer amphiphiles. Here we report the fabrication of PEtOx‐b‐PLA polymersomes at…”
Get full text
Journal Article -
16
IN VIVO APPLICATION OF LOCAL DRUG DELIVERY SYSTEMS AGAINST MEDULLOBLASTOMA GROUP 3 AND ATYPICAL/TERATOID/RHABOID TUMOURS
Published in Neuro-oncology (Charlottesville, Va.) (15-10-2024)“…Abstract AIMS Local drug delivery systems (LDDSs) applied during neurosurgery offer a means of overcoming poor blood brain barrier (BBB) permeability and have…”
Get full text
Journal Article -
17
A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes
Published in Materials Science & Engineering C (01-04-2021)“…The equipping of nanoparticles with the peptide moiety recognizing a particular receptor, enables cell or tissue-specific targeting, therefore the optimization…”
Get full text
Journal Article -
18
Hücre Içine Gen/Ilaç Taşınımına Yönelik Aktif Hedeflendirilmiş Nano Ilaç Taşıyıcı Sistemlerin Geliştirilmesi
Published 01-01-2017“…Kendiliğinden oluşum süreci, canlı sistemlerdeki (biyo)moleküllerin kendileri aralarında ve/veya su ile aralarındaki supramoleküler etkileşimleri yönetip,…”
Get full text
Dissertation