Search Results - "Oyong, Damian. A."
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Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge
Published in PLoS pathogens (01-05-2023)“…Understanding immune mechanisms that mediate malaria protection is critical for improving vaccine development. Vaccination with radiation-attenuated Plasmodium…”
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Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children
Published in EBioMedicine (01-01-2022)“…Protective malarial antibodies are acquired more rapidly in adults than children, independently of cumulative exposure, however the cellular responses…”
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Journal Article -
3
Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection
Published in Malaria journal (18-09-2019)“…Anaemia is a major consequence of malaria, caused by the removal of both infected and uninfected red blood cells (RBCs) from the circulation. Complement…”
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MAM 2024: Malaria in a changing world
Published in Trends in parasitology (01-05-2024)Get full text
Journal Article -
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Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M
Published in The Journal of infectious diseases (06-11-2019)“…Complement-fixing antibodies targeting Plasmodium vivax merozoite surface protein 3α are prevalent in both children and adults with infection, with both…”
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Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians
Published in Proceedings of the National Academy of Sciences - PNAS (12-10-2021)“…Morbidity and mortality rates from seasonal and pandemic influenza occur disproportionately in high-risk groups, including Indigenous people globally. Although…”
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Journal Article -
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Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia
Published in JCI insight (15-11-2018)“…Anemia is a major complication of malaria, driven largely by loss of uninfected RBCs during infection. RBC clearance through loss of complement regulatory…”
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Journal Article -
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Protective and Pathogenic Roles of Complement in Human Malaria
Published 01-01-2019“…Introduction: The global health burden of malaria is estimated at 200 million cases annually. Efforts to reduce malaria cases have recently stalled, calling…”
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Dissertation