Search Results - "Oyinloye, E. Babatunji"
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Atomistic simulation reveals structural mechanisms underlying D614G spike glycoprotein‐enhanced fitness in SARS‐COV‐2
Published in Journal of computational chemistry (15-09-2020)“…D614G spike glycoprotein (sgp) mutation in rapidly spreading severe acute respiratory syndrome coronavirus‐2 (SARS‐COV‐2) is associated with enhanced fitness…”
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Syringic acid demonstrates an anti-inflammatory effect via modulation of the NF-κB-iNOS-COX-2 and JAK-STAT signaling pathways in methyl cellosolve-induced hepato-testicular inflammation in rats
Published in Biochemistry and biophysics reports (01-07-2023)“…Syringic acid (SACI) is an emerging nutraceutical and antioxidant used in modern Chinese medicine. It has potential neuroprotective, anti-hyperglycemic, and…”
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Antihyperglycaemia and related gene expressions of aqueous extract of Gongronema latifolium leaf in alloxan-induced diabetic rats
Published in Pharmaceutical biology (01-01-2019)“…Context: Gongronema latifolium Benth (Asclepiadaceae) has been highly utilized in controlling diabetes mellitus traditionally in the eastern part of Nigeria…”
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Effect of syringic acid on steroid and gonadotropic hormones, hematological indices, sperm characteristics and morphologies, and markers of tissue damage in methyl cellosolve-administered rats
Published in Biochemistry and biophysics reports (01-12-2022)“…Methyl cellosolve (MTC) is an established gonadotoxic and hematotoxic compound that is commonly and universally utilized in herbicide, liquid soap, stain, dye,…”
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Ferulic acid interventions ameliorate NDEA-CCl4-induced hepatocellular carcinoma via Nrf2 and p53 upregulation and Akt/PKB-NF-κB-TNF-α pathway downregulation in male Wistar rats
Published in Toxicology reports (01-06-2024)“…Hepatocellular carcinoma is a prevalent form of liver cancer that is life threatening. Many chemically synthesized anti-cancer drugs have various degrees of…”
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Phytodentistry in Africa: prospects for head and neck cancers
Published in Clinical phytoscience (05-02-2021)“…Background Orthodox dentistry has undergone significant changes in recent times with the introduction of various omics and molecular targeted therapies both at…”
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Prospects of nanodentistry for the diagnosis and treatment of maxillofacial pathologies and cancers
Published in Heliyon (01-09-2020)“…Despite the commendable milestones achieved in molecular maxillofacial pathology in the last decade, there remains a paucity of utilization of ancillary…”
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Aframomum melegueta secondary metabolites exhibit polypharmacology against SARS‐CoV‐2 drug targets: in vitro validation of furin inhibition
Published in Phytotherapy research (01-02-2021)“…COVID‐19 pandemic is currently decimating the world's most advanced technologies and largest economies and making its way to the continent of Africa. Weak…”
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Methyl cellosolve toxicity and a review of recent treatment outcomes
Published in Comparative clinical pathology (01-12-2022)“…Methyl cellosolve (MECEL) is an industrial solvent with widespread use. Some of the products that have been known to contain MECEL include paints, nail polish,…”
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Syringic acid ameliorates testicular oxidative stress via the conservation of endogenous antioxidant markers and inhibition of the activated Nrf2-Keap1-NQO1-HO1 signaling in methyl cellosolve-administered rats
Published in Pharmacological research. Modern Chinese medicine (01-03-2023)“…Syringic acid (SYRAC) isolated from Ban Lan Gen or Isatis root, a famous Chinese traditional medicine is known to possess antiendotoxic effect. Methyl…”
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Methyl cellosolve-induced hepatic oxidative stress: The modulatory effect of syringic acid on Nrf2-Keap1-Hmox1-NQO1 signaling pathway in rats
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-05-2023)“…Syringic acid (SAC) is a phenolic compound and an antioxidant that has been identified in honey, grapes, red wine, marigold and sugar apple. Due to its potent…”
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Corrigendum to “Syringic acid ameliorates testicular oxidative stress via the conservation of endogenous antioxidant markers and inhibition of the activated Nrf2-Keap1-NQO1-HO1 signaling in methyl cellosolve-administered rats” [Pharmacological Research - Modern Chinese Medicine 6C (2023) /100207]
Published in Pharmacological research. Modern Chinese medicine (01-12-2024)Get full text
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Telemedicine as a tool to prevent multi-drug resistant tuberculosis in poor resource settings: Lessons from Nigeria
Published in Journal of clinical tuberculosis and other mycobacterial diseases (01-05-2024)“…This mini review aims to provide an overview of the role of telemedicine in preventing multi-drug resistant tuberculosis (MDR-TB) in Nigeria. The specific…”
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Interplay between heat shock proteins, inflammation and cancer: a potential cancer therapeutic target
Published in American journal of cancer research (01-01-2019)“…The historical relationship between cancer and inflammation has long been evaluated, and dates back to the early work of Virchow (1863), where he hypothesised…”
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Effect of Solanum macrocarpon Linn leaf aqueous extract on the brain of an alloxan-induced rat model of diabetes
Published in Journal of international medical research (01-06-2020)“…Objective This study was designed to evaluate the protective effect of aqueous extract of Solanum macrocarpon Linn leaf in the brain of an alloxan-induced rat…”
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Spondias mombin flavonoids showed super-binder ability with downstream molecular targets of Parkinson's disease: A structural study
Published in Informatics in medicine unlocked (2024)“…Spondias mombin is a prominent botanical resource and has garnered recognition within folkloric therapy. Parkinson's disease (PD), characterized by…”
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Green-route mediated synthesis of silver nanoparticles (AgNPs) from Syzygium cumini (L.) Skeels polyphenolic-rich leaf extracts and investigation of their antimicrobial activity
Published in IET nanobiotechnology (01-04-2018)“…Medicinal plants are widely utilised by the African population since they have no harmful side effects and low cost compared with different treatments. The…”
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Hepatoprotective effect of aqueous extract of Aframomum melegueta on ethanol-induced toxicity in rats
Published in Acta biochimica Polonica (01-01-2011)“…In recent years there have been remarkable developments in the prevention of diseases, especially with regards to the role of free radicals and antioxidants…”
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The Effects of Piper Guineense versus Sesamum Indicum Aqueous Extracts on Lipid Metabolism and Antioxidants in Hypercholesterolemic Rats
Published in Iranian journal of medical sciences (01-09-2017)“…(PG) and (SI) have been shown to be rich sources of antioxidants and other health benefits; hence, we evaluated the impact of its consumption in…”
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Comparative study on proximate, functional, mineral, and antinutrient composition of fermented, defatted, and protein isolate of Parkia biglobosa seed
Published in Food science & nutrition (01-01-2017)“…The use of plant‐derived foods in the prevention, treatment, and management of metabolic diseases especially diabetes has gained prominence; this has been…”
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