Search Results - "Oyinlade, Olutobi"

Methylated cis -regulatory elements mediate KLF4-dependent gene transactivation and cell migration by Wan, Jun, Su, Yijing, Song, Qifeng, Tung, Brian, Oyinlade, Olutobi, Liu, Sheng, Ying, Mingyao, Ming, Guo-Li, Song, Hongjun, Qian, Jiang, Zhu, Heng, Xia, Shuli

“…Altered DNA methylation status is associated with human diseases and cancer; however, the underlying molecular mechanisms remain elusive. We previously…”
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Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells by Tung, Brian, Ma, Ding, Wang, Shuyan, Oyinlade, Olutobi, Laterra, John, Ying, Mingyao, Lv, Sheng-Qing, Wei, Shuang, Xia, Shuli

“…The dismal prognosis of patients with glioblastoma (GBM) is attributed to a rare subset of cancer stem cells that display characteristics of tumor initiation,…”
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Analysis of KLF4 regulated genes in cancer cells reveals a role of DNA methylation in promoter- enhancer interactions by Oyinlade, Olutobi, Wei, Shuang, Kammers, Kai, Liu, Sheng, Wang, Shuyan, Ma, Ding, Huang, Zhi-yong, Qian, Jiang, Zhu, Heng, Wan, Jun, Xia, Shuli

“…Recent studies have revealed an unexpected role of DNA methylation at promoter regions in transcription activation. However, whether DNA methylation at…”
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Targeting UDP-α-d-glucose 6-dehydrogenase inhibits glioblastoma growth and migration by Oyinlade, Olutobi, Wei, Shuang, Lal, Bachchu, Laterra, John, Zhu, Heng, Goodwin, C. Rory, Wang, Shuyan, Ma, Ding, Wan, Jun, Xia, Shuli

“…UDP-glucose 6-dehydrogenase (UGDH) produces UDP-α- d -glucuronic acid, the precursors for glycosaminoglycans (GAGs) and proteoglycans of the extracellular…”
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Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells by Wang, Shuyan, Shi, Xiaohai, Wei, Shuang, Ma, Ding, Oyinlade, Olutobi, Lv, Sheng-Qing, Ying, Mingyao, Zhang, Yu Alex, Claypool, Steven Michael, Watkins, Paul, Xia, Shuli

“…Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor critical for the regulation of many cellular functions in both normal and neoplastic cells…”
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Heterozygous IDH1.sup.R132H/WT created by "single base editing" inhibits human astroglial cell growth by downregulating YAP by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding, Wang, Shuyan, Kratz, Lisa, Lal, Bachchu

“…Mutations in the isocitrate dehydrogenase 1 (IDH1) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome Atlas…”
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Abstract 531: Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding Ma, Wang, Shuyan, Xia, Shuli

“…Mutations in the isocitrate dehydrogenase 1 (IDH1) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome Atlas…”
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Abstract 5884: UGDH is required for KLF4-mCpG dependent increase in GBM cell migration by Oyinlade, Olutobi, Wan, Jun, Wei, Shuang, Qian, Jiang, Zhu, Heng, Xia, Shuli

“…CpG methylation in cis-regulatory elements is generally believed to repress gene expression by disrupting transcription factor (TF)-DNA interactions directly…”
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CSIG-40. HETEROZYGOUS IDH1R132H/WT CREATED BY “SINGLE BASE EDITING” INHIBITS HUMAN ASTROGLIAL CELL GROWTH AND PROMOTES CELL MIGRATION by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding, Wang, Shuyan, Qian, Jiang, Xia, Shuli

“…Abstract Mutations in the isocitrate dehydrogenase 1 (IDH1) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome…”
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Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts by Goodwin, C. Rory, Rath, Prakash, Oyinlade, Olutobi, Lopez, Hernando, Mughal, Salman, Xia, Shuli, Li, Yunqing, Kaur, Harsharan, Zhou, Xin, Ahmed, A. Karim, Ho, Sandra, Olivi, Alessandro, Lal, Bachchu

“…•C-Met and EGFR are implicated in the malignant progression of glioblastoma.•EGFRvIII and c-Met pathway inhibitors synergize to inhibit GBM tumor growth.•Stem…”
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Targeting UDP-[alpha]-d-glucose 6-dehydrogenase inhibits glioblastoma growth and migration by Oyinlade, Olutobi, Wei, Shuang, Lal, Bachchu, Laterra, John, Zhu, Heng, Goodwin, C. Rory, Wang, Shuyan, Ma, Ding, Wan, Jun, Zia, Shuli

“…UDP-glucose 6-dehydrogenase (UGDH) produces UDP-[alpha]-d-glucuronic acid, the precursors for glycosaminoglycans (GAGs) and proteoglycans of the extracellular…”
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Heterozygous IDH1 R132H/WT created by "single base editing" inhibits human astroglial cell growth by downregulating YAP by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding, Wang, Shuyan, Kratz, Lisa, Lal, Bachchu, Xu, Qingfu, Liu, Senquan, Shah, Sagar R, Zhang, Hao, Li, Yunqing, Quiñones-Hinojosa, Alfredo, Zhu, Heng, Huang, Zhi-Yong, Cheng, Linzhao, Qian, Jiang, Xia, Shuli

“…Mutations in the isocitrate dehydrogenase 1 (IDH1) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome Atlas…”
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Heterozygous IDH1R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding, Wang, Shuyan, Kratz, Lisa, Lal, Bachchu, Xu, Qingfu, Liu, Senquan, Shah, Sagar R., Zhang, Hao, Li, Yunqing, Quiñones-Hinojosa, Alfredo, Zhu, Heng, Huang, Zhi-yong, Cheng, Linzhao, Qian, Jiang, Xia, Shuli

“…Mutations in the isocitrate dehydrogenase 1 ( IDH1 ) gene have been identified in a number of cancer types, including brain cancer. The Cancer Genome Atlas…”
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Krupple Like Factor 4 (KLF4) Binding to Methylated DNA Uncovers Novel Regulatory Mechanism in Glioblastoma Migration by Oyinlade, Olutobi Z

“…Protein microarray technology provides a versatile platform for characterization of hundreds to thousands of proteins in a parallel and high-throughput manner…”
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CSIG-40. HETEROZYGOUS IDH1R132H/WT CREATED BY “SINGLE BASE EDITING” INHIBITS HUMAN ASTROGLIAL CELL GROWTH AND PROMOTES CELL MIGRATION by Wei, Shuang, Wang, Jie, Oyinlade, Olutobi, Ma, Ding, Wang, Shuyan, Qian, Jiang, Xia, Shuli

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