A Normative Study of the Components of Niprisan-an Herbal Medicine for Sickle Cell Anemia

A Normative Study of the Components of Niprisan-an Herbal Medicine for Sickle Cell Anemia

Niprisan® is an herbal medicine for sickle cell anemia developed in the National Institute for Pharmaceutical Research and Development (NIPRD). It is prepared from pepper seeds [Piper guineense Schum. & Thonn., Piperaceae], clove flower buds [Eugenia caryophyllata Thunb., Myrtaceae], caprium ste...

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Bibliographic Details
Published in:Journal of dietary supplements Vol. 7; no. 1; pp. 21 - 30
Main Authors: Obodozie, Obiageli O., Ameh, Sunday J., Afolabi, Ernest K., Oyedele, Eunice O., Ache, Theophilus A., Onanuga, Cordelia E., Ibe, Martha C., Inyang, Uford S.
Format: Journal Article
Language:English
Published: New York, NY Informa UK Ltd 01-03-2010
Taylor & Francis
Informa
Subjects:
Anemia, Sickle Cell - drug therapy
Bicarbonates - chemistry
Biological and medical sciences
Eugenia
Fabaceae
Food industries
Fundamental and applied biological sciences. Psychology
good manufacturing practice
Herbal Medicine
Humans
Hydrogen-Ion Concentration
Myrtaceae
Niprisan
normative study
Phytotherapy - standards
Piper
Piper - chemistry
Piperaceae
Plant Extracts - chemistry
Plant Extracts - standards
Plant Extracts - therapeutic use
Plants, Medicinal
Poaceae
Pterocarpus - chemistry
Quality Control
Reference Values
Research and development. New food products, dietetic foods and beverages
sickle cell anemia
Sorghum
Sorghum - chemistry
Sorghum bicolor
Species Specificity
Spectrophotometry, Atomic
Syzygium - chemistry
Niprisan
good manufacturing practice
normative study
Chemical composition
Manufacturing
herbal medicine
sickle cell anemia
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Summary:Niprisan® is an herbal medicine for sickle cell anemia developed in the National Institute for Pharmaceutical Research and Development (NIPRD). It is prepared from pepper seeds [Piper guineense Schum. & Thonn., Piperaceae], clove flower buds [Eugenia caryophyllata Thunb., Myrtaceae], caprium stem [Pterocarpus osun (L.) Craib., Fabaceae], sorghum leaves [Sorghum bicolor (L.) Moench. Poaceae], and "trona" The components were sourced from food dealers and herbalists prequalified as suppliers by the Institute's department of Medicinal Plant Research and Traditional Medicine (MPRTM), based on the criteria proposed by World Health Organization (WHO, 1998. Quality control methods for medicinal plant materials, pp. 1-115. Geneva: WHO) for the collection and handling of medicinal plant materials. The aim of the work is to establish limits for features that will influence decisions on the components. The paper describes and quantifies as per WHO guidelines of 1998 and British Pharmacopoeia (British Pharmacopoeia, 2004. Volume IV. The Stationery Office Limited, London. Appendix II D, Atomic spectrophotometry: emission and absorption, pp. A143-145. Determination of pH, pp. A143-145; Appendix VL, Determination of pH Values, pp. A199-A200, 2004.), the most striking features of these components and demonstrates that all, except Eugenia caryophyllata, exist in more than one variety. The results, including the occasional presence of lead in trona, are discussed in the context of good manufacturing practice (GMP).
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ISSN:1939-0211
1939-022X
DOI:10.3109/19390210903534988