Search Results - "Oyama, Yoko"
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Evaluation of VEGF-A in platelet and microRNA-126 in serum after coronary artery bypass grafting
Published in Heart and vessels (01-11-2021)“…Platelet functions are thought to contribute to clinical outcomes after heart surgery. This study was conducted to assess the pivotal roles of vascular…”
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VEGF-A165 is the predominant VEGF-A isoform in platelets, while VEGF-A121 is abundant in serum and plasma from healthy individuals
Published in PloS one (07-04-2023)“…Vascular endothelial growth factor A (VEGF-A) plays pivotal roles in regulating tumor angiogenesis as well as physiological vascular function. The major VEGF-A…”
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3
HMGB1 promotes the development of pulmonary arterial hypertension in rats
Published in PloS one (17-07-2014)“…Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance leading to right ventricular failure and death. Recent…”
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4
Low grade inflammation inhibits VEGF induced HUVECs migration in p53 dependent manner
Published in Biochemical and biophysical research communications (05-02-2017)“…In the course of studying crosstalk between inflammation and angiogenesis, high doses of pro-inflammatory factors have been reported to induce apoptosis in…”
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5
Dynamic changes in platelets caused by shear stress in aortic valve stenosis
Published in Clinical hemorheology and microcirculation (12-02-2021)“…Turbulent blood flow in patients with aortic valve stenosis (AS) results in morphological and functional changes in platelets and coagulation factors. The aim…”
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6
B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes
Published in The Journal of immunology (1950) (01-05-2010)“…Vascular endothelial growth factor A (VEGF-A) is a prominent growth factor for both angiogenesis and lymphangiogenesis. Recent studies have shown the…”
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Decreased Expression of Thrombomodulin in Endothelial Cells by Fibroblast Growth Factor‐23/α‐Klotho
Published in Therapeutic apheresis and dialysis (01-08-2017)“…Chronic kidney disease (CKD) has been known to be a state of excessive fibroblast growth factor‐23 (FGF23) and α‐Klotho deficiency. Patients undergoing…”
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Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats
Published in Experimental and therapeutic medicine (01-09-2013)“…The mulberry plant (Morus alba L.) contains abundant anthocyanins (ANCs), which are natural antioxidants. The aim of this study was to determine the ANC…”
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The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells
Published in The Journal of pharmacology and experimental therapeutics (01-06-2009)“…Edaravone, a potent free radical scavenger, is clinically used for the treatment of cerebral infarction in Japan. Here, we examined the effects of edaravone on…”
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10
High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy
Published in Laboratory investigation (01-06-2010)“…Granulomatous nephritis can be triggered by diverse factors and results in kidney failure. However, despite accumulating data about granulomatous inflammation,…”
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C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells
Published in Cardiovascular pathology (01-05-2008)“…Abstract Background C-reactive protein (CRP) is widely used as a sensitive biomarker for inflammation. Increasing evidence suggests that CRP plays a role in…”
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12
Edaravone: A new therapeutic approach for the treatment of acute stroke
Published in Medical hypotheses (01-12-2010)“…Summary Acute stroke, including acute ischemic stroke (AIS) and acute hemorrhagic stroke, (AHS) is a common medical problem with particular relevance to the…”
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13
Legionella pneumophila infection-mediated regulation of RICTOR via miR-218 in U937 macrophage cells
Published in Biochemical and biophysical research communications (08-01-2019)“…Inhalation of aerosolized Legionella pneumophila, a Gram-negative bacterium, can cause severe pneumonia. During infection, L. pneumophila replicates…”
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14
HMGB1: A new marker for estimation of the postmortem interval
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15
Processing grapefruit juice with γ‐cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity
Published in Journal of pharmacy and pharmacology (01-03-2020)“…Objectives Grapefruit (Citrus paradisi) juice enhances the oral bioavailability of drugs that are metabolized by intestinal cytochrome P450 3A4 (CYP3A4)…”
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Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4
Published in Biochemical and biophysical research communications (25-12-2009)“…Aquaporin-4 (AQP4) plays a role in the generation of post-ischemic edema. Pharmacological modulation of AQP4 function may thus provide a novel therapeutic…”
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Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc
Published in International journal of molecular medicine (01-05-2009)“…High mobility group box-1 protein (HMGB1), primarily from the nucleus, is released into the extracellular milieu either passively from necrotic cells or…”
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Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells
Published in Biochemical and biophysical research communications (24-07-2009)“…High mobility group box-1 (HMGB1), a non-histone DNA-binding protein, is massively released into the extracellular space from neuronal cells after ischemic…”
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19
Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells
Published in International journal of molecular medicine (01-11-2008)“…High mobility group box 1 (HMGB1) is a non-histone nuclear protein which is released from the nucleus of activated macrophages into the extracellular space in…”
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Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction
Published in Experimental and therapeutic medicine (01-09-2011)“…Edaravone was originally developed as a potent free radical scavenger and has been widely used to treat cerebral infarction in Japan since 2001. Several free…”
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