Search Results - "Oya, Shunichi"

Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors by Qu, Wenchao, Oya, Shunichi, Lieberman, Brian P, Ploessl, Karl, Wang, Limin, Wise, David R, Divgi, Chaitanya R, Chodosh, Lewis A, Chodosh, Lewis P, Thompson, Craig B, Kung, Hank F

“…Recently, there has been a renewed interest in the study of tumor metabolism above and beyond the Warburg effect. Studies on cancer cell metabolism have…”
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Binding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy subjects with [11C]-(+)-PHNO by Slifstein, Mark, Abi-Dargham, Anissa, Girgis, Ragy R, Suckow, Raymond F, Cooper, Thomas B, Divgi, Chaitanya R, Sokoloff, Pierre, Leriche, Ludovic, Carberry, Patrick, Oya, Shunichi, Joseph, Simon K, Guiraud, Marlène, Montagne, Agnès, Brunner, Valérie, Gaudoux, Florence, Tonner, Françoise

“…Rationale F17464, a dopamine D3 receptor antagonist with relatively high D3 selectivity (70 fold vs D2 in vitro ), exhibits an antipsychotic profile in…”
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Real-Time Positron Emission Tomography Evaluation of Topotecan Brain Kinetics after Ultrasound-Mediated Blood-Brain Barrier Permeability by Molotkov, Andrei, Carberry, Patrick, Dolan, Martin A, Joseph, Simon, Idumonyi, Sidney, Oya, Shunichi, Castrillon, John, Konofagou, Elisa E, Doubrovin, Mikhail, Lesser, Glenn J, Zanderigo, Francesca, Mintz, Akiva

“…Glioblastoma (GBM) is the most common primary adult brain malignancy with an extremely poor prognosis and a median survival of fewer than two years. A key…”
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F-18 Stilbenes as PET Imaging Agents for Detecting β-Amyloid Plaques in the Brain by Zhang, Wei, Oya, Shunichi, Kung, Mei-Ping, Hou, Catherine, Maier, Donna L, Kung, Hank F

“…Imaging agents targeting β-amyloid (Aβ) may be useful for diagnosis and treatment of patients with Alzheimer's disease (AD). Compounds 3e and 4e are…”
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New PET Imaging Agent for the Serotonin Transporter:  [18F]ACF (2-[(2-Amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine) by Oya, Shunichi, Choi, Seok Rye, Coenen, Heinz, Kung, Hank F

“…A new F-18-labeled phenylthiophenyl derivative specific for imaging of serotonin transporters (SERT) in the brain by positron emission tomography (PET) is…”
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In vivo imaging of vesicular monoamine transporter 2 in pancreas using an 18F epoxide derivative of tetrabenazine by Kung, Hank F., Lieberman, Brian P., Zhuang, Zhi-Ping, Oya, Shunichi, Kung, Mei-Ping, Choi, Seok Rye, Poessl, Karl, Blankemeyer, Eric, Hou, Catherine, Skovronsky, Daniel, Kilbourn, Michael

“…Development of imaging agents for pancreatic beta cell mass may provide tools for studying insulin-secreting beta cells and their relationship with diabetes…”
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In-house automated synthesis of L-[^sup 11^C]Glutamine with the use of a siemens H^sup 11^CN Box by Joseph, Simon, Sattiraju, Anirudh, Oya, Shunichi, Jurewicz, Agata, Castrillon, John, Soffing, Mark, Mintz, Akiva, Carberry, Patrick

“…Objectives: Glutamine is a readily available nutrient used for energy in both normal and tumor cells [1]. L-[11C]glutamine takes advantage of various tumor…”
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Asymmetric synthesis of tanshindiol A by Lee, Junning, Li, Jiahe, Oya, Shunichi, Snyder, John K

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Preclinical Biodistribution, Dosimetry and Toxicology of [^sup 11^C]NOP46 - a potential PET biomarker for chronic pain in humans by Oya, Shunichi, Castrillon, John, Sattiraju, Anirudh, Wasmuth, Andrew, Deng, Shixian, Zanzonico, Pat, Soffing, Mark, Wills, Alex, Carberry, Patrick, Divgi, Chaitanya, Landry, Donald, Yeh, Randy, Mintz, Akiva

“…Objectives: Chronic pain results in long-term hyper-excitability (LTH) associated with activation of protein kinase G‐1α (PKG) in the dorsal root ganglion…”
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F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Aβ aggregates in the brain by Zhang, Wei, Oya, Shunichi, Kung, Mei-Ping, Hou, Catherine, Maier, Donna L., Kung, Hank F.

“…This paper describes a novel series of 18F-labeled polyethyleneglycol (PEG)-stilbene derivatives as potential β-amyloid (Aβ) plaque-specific imaging agents for…”
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Quick Assembly of 1,4-Diphenyltriazoles as Probes Targeting β-Amyloid Aggregates in Alzheimer's Disease by Qu, Wenchao, Kung, Mei-Ping, Hou, Catherine, Oya, Shunichi, Kung, Hank F

“…Accumulation of β-amyloid aggregates (Aβ) in the brain is linked to the pathogenesis of Alzheimer's disease (AD). We report a novel approach for producing…”
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Small and neutral TcvO BAT, bisaminoethanethiol (N2S2) complexes for developing new brain imaging agents by OYA, S, PLÖSSL, K, KUNG, M.-P, STEVENSON, D. A, KUNG, H. F

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In vivo studies of the SERT-selective [18 F]FPBM and VMAT2-selective [18 F]AV-133 radiotracers in a rat model of Parkinson's disease by Wang, Julie L, Oya, Shunichi, Parhi, Ajit K, Lieberman, Brian P, Ploessl, Karl, Hou, Catherine, Kung, Hank F

“…Abstract Introduction The utility of [18 F]FPBM [2-(2′-((dimethylamino)methyl)-4′-(3-[18 F]-fluoropropoxy)phenylthio)benzenamine], a selective serotonin…”
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Fluoro-pegylated (FPEG) Imaging Agents Targeting Aβ Aggregates by Stephenson, Karin A, Chandra, Rajesh, Zhuang, Zhi-Ping, Hou, Catherine, Oya, Shunichi, Kung, Mei-Ping, Kung, Hank F

“…A novel approach of producing positron emission tomography (PET) imaging agents through the formation of bioconjugates based on a pegylation−fluorination…”
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In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine by Kung, Hank F, Lieberman, Brian P, Zhuang, Zhi-Ping, Oya, Shunichi, Kung, Mei-Ping, Choi, Seok Rye, Poessl, Karl, Blankemeyer, Eric, Hou, Catherine, Skovronsky, Daniel, Kilbourn, Michael

“…Development of imaging agents for pancreatic beta cell mass may provide tools for studying insulin-secreting beta cells and their relationship with diabetes…”
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2-(2′-((Dimethylamino)methyl)-4′-(fluoroalkoxy)-phenylthio)benzenamine Derivatives as Serotonin Transporter Imaging Agents by Parhi, Ajit K, Wang, Julie L, Oya, Shunichi, Choi, Seok-Rye, Kung, Mei-Ping, Kung, Hank F

“…A novel series of ligands with substitutions at the 5-position on phenyl ring A and at the 4′-position on phenyl ring B of…”
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FlipADAM: a potential new SPECT imaging agent for the serotonin transporter by Wang, Julie L, Deutsch, Eric C, Oya, Shunichi, Kung, Hank F

“…Abstract Introduction Single photon emission computed tomography (SPECT) imaging of the serotonin transporter (SERT) in the brain is a useful tool for…”
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In Vivo Characterization of a Series of 18 F-Diaryl Sulfides ( 18 F-2-(2′-((Dimethylamino)Methyl)-4′-(Fluoroalkoxy)Phenylthio)Benzenamine) for PET Imaging of the Serotonin Transporter by Wang, Julie L., Parhi, Ajit K., Oya, Shunichi, Lieberman, Brian, Kung, Hank F.

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In Vivo Characterization of a Series of 18F-Diaryl Sulfides (18F-2-(2'-((Dimethylamino)Methyl)-4'-(Fluoroalkoxy)Phenylthio)Benzenamine) for PET Imaging of the Serotonin Transporter by Wang, Julie L, Parhi, Ajit K, Oya, Shunichi, Lieberman, Brian, Kung, Hank F

“…PET of the serotonin transporter (SERT) in the brain is a useful tool for examining normal physiologic functions as well as disease states involving the…”
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In Vivo Characterization of a Series of ^sup 18^F-Diaryl Sulfides (^sup 18^F-2-(2'-((Dimethylamino)Methyl)-4'(Fluoroalkoxy)Phenylthio)Benzenamine) for PET Imaging of the Serotonin Transporter by Wang, Julie L, Parhi, Ajit K, Oya, Shunichi, Lieberman, Brian, Kung, Hank F

“…PET of the serotonin transporter (SERT) in the brain is a useful tool for examining normal physiologic functions as well as disease states involving the…”
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