Search Results - "Oxidative medicine and cellular longevity"
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Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
Published in Oxidative medicine and cellular longevity (2019)“…Reactive oxygen species- (ROS-) induced lipid peroxidation plays a critical role in cell death including apoptosis, autophagy, and ferroptosis. This…”
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Oxidative Stress: Harms and Benefits for Human Health
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Oxidative stress is a phenomenon caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues and the…”
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Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases
Published in Oxidative medicine and cellular longevity (2019)“…Reactive species produced in the cell during normal cellular metabolism can chemically react with cellular biomolecules such as nucleic acids, proteins, and…”
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The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing
Published in Oxidative medicine and cellular longevity (2021)“…Foot ulcers are one of the most common and severe complication of diabetes mellitus with significant resultant morbidity and mortality. Multiple factors impair…”
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ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells
Published in Oxidative medicine and cellular longevity (2019)“…Reactive oxygen species (ROS) are by-products of normal cell activity. They are produced in many cellular compartments and play a major role in signaling…”
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PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism
Published in Oxidative medicine and cellular longevity (2020)“…Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α is a transcriptional coactivator described as a master regulator of mitochondrial biogenesis…”
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Molecular Mechanisms Linking Oxidative Stress and Diabetes Mellitus
Published in Oxidative medicine and cellular longevity (2020)“…Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by chronic hyperglycemia and an inadequate response to circulatory…”
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Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
Published in Oxidative medicine and cellular longevity (2019)“…The transcription factor NRF2 (nuclear factor erythroid 2-related factor 2) triggers the first line of homeostatic responses against a plethora of…”
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The Keap1-Nrf2 System: A Mediator between Oxidative Stress and Aging
Published in Oxidative medicine and cellular longevity (2021)“…Oxidative stress, a term that describes the imbalance between oxidants and antioxidants, leads to the disruption of redox signals and causes molecular damage…”
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Targeting Early Atherosclerosis: A Focus on Oxidative Stress and Inflammation
Published in Oxidative medicine and cellular longevity (2019)“…Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress and endothelial dysfunction. Oxidation of low-density lipoprotein…”
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Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only…”
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Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine
Published in Oxidative medicine and cellular longevity (2020)“…Quercetin is a flavonoid compound widely present in plants and exhibits a variety of biological activities. Research on quercetin has shown its potential for…”
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Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Oxidative stress is viewed as an imbalance between the production of reactive oxygen species (ROS) and their elimination by protective mechanisms, which can…”
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ROS and ROS-Mediated Cellular Signaling
Published in Oxidative medicine and cellular longevity (01-01-2016)“…It has long been recognized that an increase of reactive oxygen species (ROS) can modify the cell-signaling proteins and have functional consequences, which…”
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Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Liver steatosis without alcohol consumption, namely, nonalcoholic fatty liver disease (NAFLD), is a common hepatic condition that encompasses a wide spectrum…”
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Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential
Published in Oxidative medicine and cellular longevity (2022)“…Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary metabolite in many plant taxa. EA content is considerable in…”
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Oxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Age is the main risk factor for a number of human diseases, including neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and…”
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A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity
Published in Oxidative medicine and cellular longevity (2022)“…Pesticides are important chemicals or biological agents that deter or kill pests. The use of pesticides has continued to increase as it is still considered the…”
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Reactive Oxygen Species (ROS) Regulates Different Types of Cell Death by Acting as a Rheostat
Published in Oxidative medicine and cellular longevity (2021)“…Reactive oxygen species (ROS) are essential for cellular signaling and response to stress. The level of ROS and the type of ROS determine the ability of cells…”
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Oxidative Stress and Advanced Lipoxidation and Glycation End Products (ALEs and AGEs) in Aging and Age-Related Diseases
Published in Oxidative medicine and cellular longevity (2019)“…Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living organisms and is denoted as a persistent condition of an imbalance…”
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