Search Results - "Owley, Thomas"

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes by Bucan, Maja, Abrahams, Brett S, Wang, Kai, Glessner, Joseph T, Herman, Edward I, Sonnenblick, Lisa I, Alvarez Retuerto, Ana I, Imielinski, Marcin, Hadley, Dexter, Bradfield, Jonathan P, Kim, Cecilia, Gidaya, Nicole B, Lindquist, Ingrid, Hutman, Ted, Sigman, Marian, Kustanovich, Vlad, Lajonchere, Clara M, Singleton, Andrew, Kim, Junhyong, Wassink, Thomas H, McMahon, William M, Owley, Thomas, Sweeney, John A, Coon, Hilary, Nurnberger, John I, Li, Mingyao, Cantor, Rita M, Minshew, Nancy J, Sutcliffe, James S, Cook, Edwin H, Dawson, Geraldine, Buxbaum, Joseph D, Grant, Struan F A, Schellenberg, Gerard D, Geschwind, Daniel H, Hakonarson, Hakon

“…The genetics underlying the autism spectrum disorders (ASDs) is complex and remains poorly understood. Previous work has demonstrated an important role for…”
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Treatment of individuals with autism spectrum disorders in the emergency department: Special considerations by Owley, Thomas B.

“…Because of their particular difficulties in social interactions and language and communication, individuals with autism spectrum disorders (ASDs) present to…”
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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes by Minshew, Nancy J, Thomas, Kelly, Nurnberger, John I, Crawford, Emily L, Otieno, Frederick, Dawson, Geraldine, Posey, David J, Annaiah, Kiran, Glaberson, Wendy, Wood, Shawn, Meyer, Kacie J, Sleiman, Patrick M. A, Miller, Judith, Munson, Jeffrey, Kim, Cecilia E, Bradfield, Jonathan P, Soorya, Latha, Frackelton, Edward C, Bucan, Maja, Sakurai, Takeshi, Hou, Cuiping, Anagnostou, Evdokia, Piven, Joseph, Schultz, Robert T, Zhang, Haitao, Cook, Edwin H, Schellenberg, Gerard D, Wang, Kai, Flory, James, Rudd, Danielle S, Sweeney, John A, Zurawiecki, Danielle, Grant, Struan F. A, Michaels, Shana, Levy, Susan E, Chiavacci, Rosetta, McMahon, William M, Brune, Camille W, Korvatska, Olena, Klei, Lambertus, Cai, Guiqing, McDougle, Christopher J, Hakonarson, Hakon, Kolevzon, Alexander, Garris, Maria, Silverman, Jeremy M, Wassink, Thomas H, Owley, Thomas, Glessner, Joseph T, Sutcliffe, James S, Reichert, Jennifer, Davis, Lea K, Bernier, Raphael, Game, Rachel M, Devlin, Bernie, Coon, Hilary, Imielinski, Marcin, Estes, Annette, Buxbaum, Joseph D

“…Autism spectrum disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies focusing on candidate genes or…”
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The SOFIA Study: Negative Multi-center Study of Low Dose Fluoxetine on Repetitive Behaviors in Children and Adolescents with Autistic Disorder by Herscu, Paul, Handen, Benjamin L., Arnold, L. Eugene, Snape, Michael F., Bregman, Joel D., Ginsberg, Lawrence, Hendren, Robert, Kolevzon, Alexander, Melmed, Raun, Mintz, Mark, Minshew, Nancy, Sikich, Linmarie, Attalla, Ashraf, King, Brian, Owley, Thomas, Childress, Ann, Chugani, Harry, Frazier, Jean, Cartwright, Charles, Murphy, Tanya

“…Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that reduces obsessive–compulsive symptoms. There is limited evidence supporting its efficacy for…”
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Common genetic variants on 5p14.1 associate with autism spectrum disorders by Hakonarson, Hakon, Wang, Kai, Zhang, Haitao, Ma, Deqiong, Bucan, Maja, Glessner, Joseph T, Abrahams, Brett S, Salyakina, Daria, Imielinski, Marcin, Bradfield, Jonathan P, Sleiman, Patrick M. A, Kim, Cecilia E, Hou, Cuiping, Frackelton, Edward, Chiavacci, Rosetta, Takahashi, Nagahide, Sakurai, Takeshi, Rappaport, Eric, Lajonchere, Clara M, Munson, Jeffrey, Estes, Annette, Korvatska, Olena, Piven, Joseph, Sonnenblick, Lisa I, Alvarez Retuerto, Ana I, Herman, Edward I, Dong, Hongmei, Hutman, Ted, Sigman, Marian, Ozonoff, Sally, Klin, Ami, Owley, Thomas, Sweeney, John A, Brune, Camille W, Cantor, Rita M, Bernier, Raphael, Gilbert, John R, Cuccaro, Michael L, McMahon, William M, Miller, Judith, State, Matthew W, Wassink, Thomas H, Coon, Hilary, Levy, Susan E, Schultz, Robert T, Nurnberger, John I, Haines, Jonathan L, Sutcliffe, James S, Cook, Edwin H, Minshew, Nancy J, Buxbaum, Joseph D, Dawson, Geraldine, Grant, Struan F. A, Geschwind, Daniel H, Pericak-Vance, Margaret A, Schellenberg, Gerard D

“…Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental and neuropsychiatric disorders characterized by deficits in verbal…”
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Escitalopram pharmacogenetics: CYP2C19 relationships with dosing and clinical outcomes in autism spectrum disorder by Bishop, Jeffrey R, Najjar, Fedra, Rubin, Leah H, Guter, Stephen J, Owley, Thomas, Mosconi, Matthew W, Jacob, Suma, Cook, Edwin H

“…BACKGROUND AND AIMSelective serotonin reuptake inhibitors such as escitalopram are commonly used to treat patients with autism spectrum disorder (ASD), but…”
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A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders by Owley, Thomas, Salt, Jeff, Guter, Stephen, Grieve, Adam, Walton, Laura, Ayuyao, Nelson, Leventhal, Bennett L, Cook, Jr, Edwin H

“…This pilot study examined the effectiveness of memantine hydrochloride in improving cognitive functioning and behavioral symptoms in children with pervasive…”
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Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism by Najjar, Fedra, Owley, Thomas, Mosconi, Matthew W, Jacob, Suma, Hur, Kwan, Guter, Stephen J, Sweeney, John A, Gibbons, Robert D, Cook, Edwin H, Bishop, Jeffrey R

“…The purpose of this study was to determine whether polymorphisms in the serotonin transporter (SLC6A4) and serotonin-2A receptor (HTR2A) genes are associated…”
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An Open-Label Trial of Escitalopram in Pervasive Developmental Disorders by Owley, Thomas, Walton, Laura, Salt, Jeff, Guter, Stephen J., Jr, Winnega, Marrea, Leventhal, Bennett L, Cook, Edwin H., Jr

“…Objective: To assess the effect of escitalopram in the treatment of pervasive developmental disorders (PDDs). Method: This 10-week study had a forced…”
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A pharmacogenetic study of escitalopram in autism spectrum disorders by Owley, Thomas, Brune, Camille W., Salt, Jeff, Walton, Laura, Guter, Steve, Ayuyao, Nelson, Gibbons, Robert D., Leventhal, Bennett L., Cook, Edwin H.

“…Objective: To determine the effect of serotonin transporter polymorphism promoter region (5‐HTTPLR) genotypic variation (low, intermediate, and high expression…”
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Utility of the Gilliam Autism Rating Scale in Research and Clinical Populations by South, Mikle, Williams, Brenda J, McMahon, William M, Owley, Thomas, Filipek, Pauline A, Shernoff, E, Corsello, Christina, Lainhart, Janet E, Landa, Rebecca, Ozonoff, Sally

“…A study examined the validity of the Gilliam Autism Rating Scale (GARS) with 119 children (ages 3-10) with strict DSM-IV (Diagnostic Statistical Manual of…”
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Multisite, double-blind, placebo-controlled trial of porcine secretin in autism by Owley, T, McMahon, W, Cook, E H, Laulhere, T, South, M, Mays, L Z, Shernoff, E S, Lainhart, J, Modahl, C B, Corsello, C, Ozonoff, S, Risi, S, Lord, C, Leventhal, B L, Filipek, P A

“…To examine the efficacy of intravenous porcine secretin for the treatment of autistic disorder. Randomized, double-blind, placebo-controlled, crossover design…”
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Genome-Wide Analyses of Exonic Copy Number Variants in a Family-Based Study Point to Novel Autism Susceptibility Genes: e1000536 by Bucan, Maja, Abrahams, Brett S, Wang, Kai, Glessner, Joseph T, Herman, Edward I, Sonnenblick, Lisa I, Retuerto, Ana IAlvarez, Imielinski, Marcin, Hadley, Dexter, Bradfield, Jonathan P, Kim, Cecilia, Gidaya, Nicole B, Lindquist, Ingrid, Hutman, Ted, Sigman, Marian, Kustanovich, Vlad, Lajonchere, Clara M, Singleton, Andrew, Kim, Junhyong, Wassink, Thomas H, McMahon, William M, Owley, Thomas, Sweeney, John A, Coon, Hilary, Jr, John INurnberger, Li, Mingyao, Cantor, Rita M, Minshew, Nancy J, Sutcliffe, James S, Cook, Edwin H, Dawson, Geraldine, Buxbaum, Joseph D, Grant, Struan FA, Schellenberg, Gerard D, Geschwind, Daniel H, Hakonarson, Hakon

“…The genetics underlying the autism spectrum disorders (ASDs) is complex and remains poorly understood. Previous work has demonstrated an important role for…”
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Impact of recent findings on study design of future autism clinical trials by Hollander, Eric, Phillips, Ann, King, Bryan H, Guthrie, Donald, Aman, Michael G, Law, Paul, Owley, Thomas, Robinson, Ricki

“…There are specific challenges to studying the design of pharmacologic trials in child/adolescent and adult autism, such as subject stratification and parallel…”
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EPS or stereotypies? by Owley, Thomas, Leventhal, Bennett, Cook, Edwin H

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Case series: Adderall augmentation of serotonin reuptake inhibitors in childhood-onset obsessive compulsive disorder by Owley, Thomas, Owley, Soyna, Leventhal, Bennett, Cook, Jr, Edwin H

“…Current pharmacological treatment of obsessive compulsive disorder involves the use of selective serotonin reuptake inhibitors (SSRIs). However, a large…”
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Risperidone-induced prolonged erections following the addition of lithium by Owley, T, Leventhal, B, Cook, Jr, E H

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New-onset narcolepsy and paroxetine by Owley, T, Flaherty, J

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THE DEVELOPMENT OF THE CHILD'S CONCEPT OF ECOLOGY by OWLEY, GORDON THOMAS

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