Search Results - "Owji, Ali A."

Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis by Walker, Alyssa C, Bhargava, Rohan, Dove, Autumn S, Brust, Amanda S, Owji, Ali A, Czyż, Daniel M

“…Neurodegenerative protein conformational diseases are characterized by the misfolding and aggregation of metastable proteins encoded within the host genome…”
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Autophagy and apoptosis dysfunction in neurodegenerative disorders by Ghavami, Saeid, Shojaei, Shahla, Yeganeh, Behzad, Ande, Sudharsana R, Jangamreddy, Jaganmohan R, Mehrpour, Maryam, Christoffersson, Jonas, Chaabane, Wiem, Moghadam, Adel Rezaei, Kashani, Hessam H, Hashemi, Mohammad, Owji, Ali A, Łos, Marek J

“…Autophagy and apoptosis are basic physiologic processes contributing to the maintenance of cellular homeostasis. Autophagy encompasses pathways that target…”
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Time-off-pick Assay to Measure Caenorhabditis elegans Motility by Walker, Alyssa C, Bhargava, Rohan, Brust, Amanda S, Owji, Ali A, Czyż, Daniel M

“…is a simple metazoan that is often used as a model organism to study various human ailments with impaired motility phenotypes, including protein conformational…”
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Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene‐related peptide (CGRP) receptors in dissociated rat spinal cord cell culture by Takhshid, Mohammad A, Poyner, David R, Chabot, Jean‐Guy, Fournier, Alain, Ma, Weiya, Zheng, Wen‐Hua, Owji, Ali A, Quirion, Remi

“…1 Adrenomedullin (AM) and calcitonin gene‐related peptide (CGRP) have structural similarities, interact with each others receptors (calcitonin receptor‐like…”
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A rat skeletal muscle cell line (L6) expresses specific adrenomedullin binding sites but activates adenylate cyclase via calcitonin gene-related peptide receptors by Coppock, H A, Owji, A A, Bloom, S R, Smith, D M

“…We have previously demonstrated specific binding sites for adrenomedullin, a novel member of the calcitonin family of peptides, in rat muscles. It is unclear…”
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Binding sites for islet amyloid polypeptide in mammalian lung: species variation and effects on adenylyl cyclase by Bhogal, R, Smith, D M, Owji, A A, Bloom, S R

“…Islet amyloid polypeptide (IAPP) and calcitonin gene related peptide (CGRP) share a 47% sequence homology. IAPP can interact with adenylyl cyclase coupled CGRP…”
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An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat by Owji, A A, Smith, D M, Coppock, H A, Morgan, D G, Bhogal, R, Ghatei, M A, Bloom, S R

“…Rat adrenomedullin is a novel 50-amino acid peptide with structural similarities to the calcitonin family of peptides, calcitonin, calcitonin gene-related…”
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Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity by Coppock, H A, Owji, A A, Austin, C, Upton, P D, Jackson, M L, Gardiner, J V, Ghatei, M A, Bloom, S R, Smith, D M

“…Rat-2 fibroblasts demonstrate specific binding of 125I-labelled rat adrenomedullin (KD=0.43 nM; Bmax=50 fmol/mg of protein) in the absence of 125I-labelled…”
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Glucagon-like peptide-1 is a physiological incretin in rat by Wang, Z, Wang, R M, Owji, A A, Smith, D M, Ghatei, M A, Bloom, S R

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Angiotensin II receptor expression and inhibition in the chronically hypoxic rat lung by Zhao, Lan, Al‐Tubuly, Rida, Sebkhi, Abdelkrim, Owji, Ali A., Nunez, Derek J.R., Wilkins, Martin R.

“…1 Angiotensin II (All) binding density and the effect of chronic All receptor blockade were examined in the rat model of hypoxia‐induced pulmonary…”
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Characterisation and molecular identification of adrenomedullin binding sites in the rat spinal cord: a comparison with calcitonin gene-related peptide receptors by Owji, A A, Gardiner, J V, Upton, P D, Mahmoodi, M, Ghatei, M A, Bloom, S R, Smith, D M

“…Calcitonin gene-related peptide (CGRP) and its receptors are found in mammalian spinal cord. We show, for the first time, binding sites for the novel related…”
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Adrenomedullin activity in chronically hypoxic rat lungs by Zhao, L, Brown, L A, Owji, A A, Nunez, D J, Smith, D M, Ghatei, M A, Bloom, S R, Wilkins, M R

“…Adrenomedullin (AM) is a novel vasodilator with structural similarities to calcitonin gene-related peptide (CGRP). This study investigated AM activity in the…”
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Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity by COPPOCK, Hedley A., OWJI, Ali A., AUSTIN, Carol, UPTON, Paul D., JACKSON, Mary L., GARDINER, James V., GHATEI, Mohammad A., BLOOM, Stephen R., SMITH, David M.

“…Rat-2 fibroblasts demonstrate specific binding of 125I-labelled rat adrenomedullin (KD = 0.43nM; Bmax = 50fmol/mg of protein) in the absence of 125I-labelled…”
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Specific adrenomedullin binding sites and hypotension in the rat systemic vascular bed by Nandha, Kiran A., Taylor, Gillian M., Smith, David M., Owji, Ali A., Byfield, Peter G.H., Ghatei, Mohammad A., Bloom, Stephen R.

“…The potent vasodilator peptide, adrenomedullin, has been shown to be present in plasma, suggesting a physiological role in cardiovascular control. Here we…”
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UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53 by Shafiee, Sayed Mohammad, Rasti, Mozhgan, Seghatoleslam, Atefeh, Azimi, Tayebeh, Owji, Ali Akbar

“…The p53 tumor suppressor protein is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage. p53 is a…”
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