Search Results - "Owings, Joshua P"
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Analysis of the Pseudomonas aeruginosa Regulon Controlled by the Sensor Kinase KinB and Sigma Factor RpoN
Published in Journal of Bacteriology (01-03-2012)“…Alginate overproduction by Pseudomonas aeruginosa, also known as mucoidy, is associated with chronic endobronchial infections in cystic fibrosis. Alginate…”
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Lysine trimethylation of EF-Tu mimics platelet-activating factor to initiate Pseudomonas aeruginosa pneumonia
Published in mBio (01-07-2013)“…Pseudomonas aeruginosa is a ubiquitous microorganism and the most common Gram-negative bacterium associated with nosocomial pneumonia, which is a leading cause…”
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Substrate recognition by the Pseudomonas aeruginosa EF-Tu–modifying methyltransferase EftM
Published in The Journal of biological chemistry (27-12-2019)“…The opportunistic bacterial pathogen Pseudomonas aeruginosa is a leading cause of serious infections in individuals with cystic fibrosis, compromised immune…”
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4
Auranofin and N-heterocyclic carbene gold-analogs are potent inhibitors of the bacteria Helicobacter pylori
Published in FEMS microbiology letters (01-07-2016)“…Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis. Recent reports of antimicrobial activity against protozoa…”
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Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase
Published in The Journal of biological chemistry (12-02-2016)“…Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that trimethylates elongation factor-thermo-unstable (EF-Tu) on lysine 5. Lysine 5 methylation…”
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Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains
Published in BMC genomics (30-10-2015)“…Pseudomonas aeruginosa is an environmentally ubiquitous Gram-negative bacterium and important opportunistic human pathogen, causing severe chronic respiratory…”
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A unique, highly conserved secretory invertase is differentially expressed by promastigote developmental forms of all species of the human pathogen, Leishmania
Published in Molecular and cellular biochemistry (01-06-2015)“…Leishmania are protozoan pathogens of humans that exist as extracellular promastigotes in the gut of their sand fly vectors and as obligate intracellular…”
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Diverse viscerotropic isolates of Leishmania all express a highly conserved secretory nuclease during human infections
Published in Molecular and cellular biochemistry (01-02-2012)“…Previously, we characterized a gene encoding the unique nuclease ( Ld Nuc s ) from a Sudanese isolate of the human pathogen Leishmania donovani. This parasite…”
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Molecular and Functional Characterization of a Unique Secretory Nuclease [ Ld Nuc s ] from the Human Protozoan Pathogen, Leishmania donovani
Published in The FASEB journal (01-03-2008)“…Abstract only Leishmania are parasites of humans that reside/multiply as promastigotes within the gut of their sandfly vectors and as obligate intracellular…”
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Molecular and Functional Analyses of a Novel Secretory Nuclease from the Human Pathogen Leishmania donovani
Published in The FASEB journal (01-04-2007)“…Leishmania are protozoan pathogens of humans that reside/multiply as promastigotes in the gut of their sandfly vectors and as amastigotes in the…”
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