Search Results - "Owerbach, D"
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The search for IDDM susceptibility genes: the next generation
Published in Diabetes (New York, N.Y.) (01-05-1996)“…The search for IDDM susceptibility genes: the next generation. D Owerbach and K H Gabbay Department of Pediatrics, Baylor College of Medicine, Houston, TX…”
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Physical and genetic mapping of IDDM8 on chromosome 6q27
Published in Diabetes (New York, N.Y.) (01-03-2000)“…Physical and genetic mapping of IDDM8 on chromosome 6q27. D Owerbach Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA…”
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Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene
Published in Diabetes (New York, N.Y.) (01-12-1993)“…Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene. D Owerbach and K H Gabbay Diabetes…”
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Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35
Published in Diabetes (New York, N.Y.) (01-06-1997)“…Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35. D Owerbach , F J…”
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Pro-453 to Ser mutation in CYP21 is associated with nonclassic steroid 21-hydroxylase deficiency
Published in Molecular endocrinology (Baltimore, Md.) (01-08-1992)“…Steroid 21-hydroxylase deficiency is the leading cause of impaired cortisol synthesis in congenital adrenal hyperplasia (CAH), with the nonclassic form (NC)…”
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Primary association of HLA-DQw8 with type I diabetes in DR4 patients
Published in Diabetes (New York, N.Y.) (01-07-1989)“…Primary association of HLA-DQw8 with type I diabetes in DR4 patients. D Owerbach , S Gunn and K H Gabbay Department of Pediatrics, Baylor College of Medicine,…”
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Restriction fragment length polymorphism of the insulin gene in diabetes mellitus
Published in Diabetes (New York, N.Y.) (01-03-1982)“…Restriction fragment length polymorphism of the insulin gene in diabetes mellitus. D Owerbach and J Nerup Abstract Variant DNA sequences flanking the human…”
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Salt-wasting congenital adrenal hyperplasia: detection and characterization of mutations in the steroid 21-hydroxylase gene, CYP21, using the polymerase chain reaction
Published in The journal of clinical endocrinology and metabolism (01-03-1992)“…We have characterized mutations in the steroid 21-hydroxylase gene (CYP21) in salt-wasting congenital adrenal hyperplasia (SW-CAH) subjects, healthy control…”
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The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes
Published in Diabetes (New York, N.Y.) (01-01-1995)“…The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes. D Owerbach and K H Gabbay Department of…”
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A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus
Published in The Journal of biological chemistry (25-06-2004)“…Three SUMO (small ubiquitin-related modifier) genes have been identified in humans, which tag proteins to modulate subcellular localization and/or enhance…”
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Linkage of the VNTR/insulin-gene and type I diabetes mellitus : increased gene sharing in affected sibling pairs
Published in American journal of human genetics (01-05-1994)“…Ninety-six multiplex type I diabetic families were typed at the 5' flanking region of the insulin gene by using a PCR assay that better resolves the VNTR into…”
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A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation
Published in Biochemical and biophysical research communications (18-11-2005)“…Four small ubiquitin-related modifier (SUMO) genes have been identified in humans. However, little is known about the basic biology of SUMO-4. Here, we report…”
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13
The insulin gene is located on the short arm of chromosome 11 in humans
Published in Diabetes (New York, N.Y.) (01-01-1981)“…The insulin gene is located on the short arm of chromosome 11 in humans. D Owerbach , G I Bell , W J Rutter , J A Brown and T B Shows Abstract The human…”
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Primary association of HLA-DQw8 with type I diabetes in DR4 patients
Published in Diabetes (New York, N.Y.) (01-07-1989)“…DNA from 164 Caucasian type I (insulin-dependent) diabetic patients and 200 Caucasian nondiabetic control blood donors were analyzed by the polymerase chain…”
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Multigenic basis for type I diabetes. Association of HRAS1 polymorphism with HLA-DR3, DQw2/DR4, DQw8
Published in Diabetes (New York, N.Y.) (01-12-1990)“…Multigenic basis for type I diabetes. Association of HRAS1 polymorphism with HLA-DR3, DQw2/DR4, DQw8. D Owerbach , S Gunn and K H Gabbay Department of…”
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16
Restriction fragment length polymorphism of the insulin gene in diabetes mellitus
Published in Diabetes (New York, N.Y.) (01-03-1982)“…Variant DNA sequences flanking the human insulin gene were found in the Danish population using restriction endonucleases (restriction fragment length…”
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Susceptibility to insulin-dependent diabetes defined by restriction enzyme polymorphism of HLA-D region genomic DNA
Published in Diabetes (New York, N.Y.) (01-10-1984)“…Susceptibility to insulin-dependent diabetes defined by restriction enzyme polymorphism of HLA-D region genomic DNA. D Owerbach , B Hägglöf , A Lernmark and G…”
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Tissue-Specific Expression of Transfected Human Insulin Genes in Pluripotent Clonal Rat Insulinoma Lines Induced during Passage in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1988)“…The pluripotent rat islet tumor cell line MSL-G2 expresses primarily glucagon or cholecystokinin and not insulin in vitro but changes phenotype completely…”
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Leukocyte and Fibroblast Interferon Genes are Located on Human Chromosome 9
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1981)“…At least eight leukocyte interferon genes (IFL) and the single fibroblast interferon gene (IFF) have been located on chromosome 9 in humans. In somatic cell…”
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DNA analysis of HLA-DR, DQ, and DP alleles in children with polyarticular juvenile rheumatoid arthritis
Published in Journal of rheumatology (01-10-1992)“…HLA-DR, DQ and DP alleles were determined by restriction fragment length polymorphism analysis and oligonucleotide probe hybridization of polymerase chain…”
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