Evaluation of the etiology of persistent iritis after cataract surgery

Evaluation of the etiology of persistent iritis after cataract surgery

Background The purpose of this study was to evaluate patients with persistent iritis after cataract surgery to determine its incidence and risk factors. Adjusting the management of patients at risk could allow for a more predictable post-operative course and outcome. A retrospective chart review was...

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Bibliographic Details
Published in:Journal of ophthalmic inflammation and infection Vol. 9; no. 1; pp. 4 - 7
Main Authors: Neatrour, Kristin, McAlpine, Allison, Owens, Timothy Brooks, Trivedi, Rupal H., Poole Perry, Lynn J.
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 18-02-2019
Springer Nature B.V
SpringerOpen
Subjects:
Cataract surgery complications
Cataracts
Diabetes
Diabetic retinopathy
Epidemiology
Etiology
Eye surgery
Infections
Inflammation
Iritis
Medicine
Medicine & Public Health
Ophthalmology
Original Research
Oxidative stress
Patients
Post-operative management
Post-operative uveitis
Race
Rheumatoid arthritis
Risk factors
Studies
Surgical outcomes
Trends
Iritis
Pseudophakia
Cataract surgery complications
Post-operative management
Inflammation
Epidemiology
Post-operative uveitis
Risk factors
Incidence
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Summary:Background The purpose of this study was to evaluate patients with persistent iritis after cataract surgery to determine its incidence and risk factors. Adjusting the management of patients at risk could allow for a more predictable post-operative course and outcome. A retrospective chart review was performed of patients who had post-operative iritis longer than 1 month after cataract surgery during a 2-year period at Storm Eye Institute at the Medical University of South Carolina (MUSC) in Charleston, South Carolina. Patient demographics and various pre-operative, intra-operative, and post-operative factors were analyzed for trends. Results Thirty-nine patients (49 eyes) met the inclusion criteria, and this group was compared to a control cohort of 40 patients (66 eyes) who did not have persistent iritis after cataract surgery. The overall incidence of post-operative iritis was 1.75%. In all patients with post-operative iritis lasting greater than 1 month, African American race and pupil expansion device use were statistically significant factors. After excluding patients with a history of ocular inflammation or known inflammatory or autoimmune diagnosis (1.20% incidence), there were still a significantly higher proportion of African Americans compared to the control group. When patients with post-operative iritis of less than 6 months in duration were additionally excluded, the incidence was 0.32%, and history of diabetes was statistically significant in addition to race. Conclusions Risk factors for persistent iritis after cataract surgery include being diabetic, of African American racial background, and pupil expansion device use. These patients can be better informed of the higher risk of prolonged inflammation in their post-operative course, and peri-operative management can be tailored accordingly.
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ISSN:1869-5760
1869-5760
DOI:10.1186/s12348-019-0170-2