Search Results - "Owens, P. K."

Immobilisation and evaluation of a vancomycin chiral stationary phase for capillary electrochromatography by Wikström, H, Svensson, L.A, Torstensson, A, Owens, P.K

“…The macrocyclic antibiotic, vancomycin, is covalently bonded to LiChrospher ® diol silica packed columns and evaluated in capillary electrochromatography (CEC)…”
Get full text

Non-particulate (continuous bed or monolithic) acrylate-based capillary columns for reversed-phase liquid chromatography and electrochromatography by Kornyšova, O., Maruška, A., Owens, P.K., Erickson, M.

“…Three approaches are described to synthesize acrylic non-particulate beds (also called continuous beds or monoliths) in aqueous polymerization media for…”
Get full text

Validation of a chiral capillary electrochromatographic method for metoprolol on a teicoplanin stationary phase by CARLSSON, E, WIKSTRÖM, H, OWENS, P. K

Get full text

Molecular imprinting for bio- and pharmaceutical analysis by Owens, P.K, Karlsson, L, Lutz, E.S.M, Andersson, L.I

“…The potential of analytical techniques based on molecular imprinting is reviewed from the viewpoint of bio- and pharmaceutical analysis. A literature study…”
Get full text

Peak compression in semi-preparative supercritical fluid chromatography by OWENS, P. K, GYLLENHAAL, O, KARLSSON, A, KARLSSON, L

Get full text

Evaluation of a Vancomycin Chiral Stationary Phase in Capillary Electrochromatography Using Polar Organic and Reversed-Phase Modes by Karlsson, Charlotte, Karlsson, Lars, Armstrong, Daniel W, Owens, Paul K

“…A vancomycin chiral stationary phase (CSP) was fully evaluated in capillary electrochromatography (CEC) in reversed-phase and polar organic modes for a number…”
Get full text

Enantioselective reversed-phase and non-aqueous capillary electrochromatography using a teicoplanin chiral stationary phase by Karlsson, Charlotte, Wikström, Håkan, Armstrong, Daniel W, Owens, Paul K

“…Enantiomeric separation of chiral pharmaceuticals is carried out in aqueous and non-aqueous packed capillary electrochromatography (CEC) using a teicoplanin…”
Get full text

Continuous beds with vancomycin as chiral stationary phase for capillary electrochromatography by Kornyšova, Olga, Owens, Paul K., Maruška, Audrius

“…Enantiomeric separations in capillary electrochromatography (CEC) carried out using a continuous‐bed chiral stationary phase (CSP) based on the macrocyclic…”
Get full text

Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases by Svensson, L A, Owens, P K

“…Racemic mixtures of five acidic drugs have been successfully separated by supercritical fluid chromatography (SFC) using macrocyclic antibiotic chiral…”
Get more information

Application of molecularly imprinted polymers in supercritical fluid chromatography by Ellwanger, Arndt, Owens, Paul K., Karlsson, Lars, Bayoudh, Sami, Cormack, Peter, Sherrington, David, Sellergren, Börje

“…Molecularly imprinted polymers (MIPs), for the templates free base racemic propranolol and the l-enantiomer of phenylalanine anilide ( l-PA), were investigated…”
Get full text

Direct separation of captopril diastereoisomers including their rotational isomers by RP-LC using a teicoplanin column by OWENS, Paul K, SVENSSON, Lars A, VESSMAN, Jörgen

“…A direct reversed-phase liquid chromatography (LC) method has been developed for the separation and analysis of captopril and its 2R,2S diastereoisomer using a…”
Get full text

Effect of charged and uncharged chiral additives on the resolution of amlodipine enantiomers in liquid chromatography and capillary electrophoresis by Owens, Paul K, Fell, Anthony F, Coleman, Michael W, Berridge, John C

“…Neutral cyclodextrins (CDs) and derivatives carrying an overall cationic or anionic charge are widely utilised as chiral additives in liquid chromatography…”
Get full text

Screening of cyclodextrins by nuclear magnetic resonance for the design of chiral capillary electrophoresis separations by Owens, Paul K, Fell, Anthony F, Coleman, Michael W, Berridge, John C

“…High-field one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) spectroscopy and capillary electrophoresis (CE) are examined to…”
Get full text

Chiral recognition in liquid chromatography utilising chargeable cyclodextrins for resolution of doxazosin enantiomers by Owens, Paul K., Fell, Anthony F., Coleman, Michael W., Berridge, John C.

“…The chromatographic resolution of rac‐doxazosin using reversed‐phase high performance liquid chromatography (HPLC) with the chargeable chiral mobile phase…”
Get full text

Use of 1H-NMR spectroscopy to determine the enantioselective mechanism of neutral and anionic cyclodextrins in capillary electrophoresis by Owens, Paul K., Fell, Anthony F., Coleman, Michael W., Kinns, Michael, Berridge, John C.

“…One-dimensional (1D) and two-dimensional (2D) 1H nuclear magnetic resonance (NMR) techniques have been used to investigate the chiral recognition process in…”
Get full text

Method development in liquid chromatography with a charged cyclodextrin additive for chiral resolution of rac-amlodipine utilising a central composite design by Owens, Paul K., Fell, Anthony F., Coleman, Michael W., Berridge, John C.

“…A negatively charged derivative of β‐cyclodextrin, sulphobutyl ether‐β‐cyclodextrin (SBE‐β‐CD), was examined as a chiral mobile phase additive in…”
Get full text

Separation of the voriconazole stereoisomers by capillary electrophoresis and liquid chromatography by Owens, P K, Fell, A F, Coleman, M W, Berridge, J C

“…A chiral capillary electrophoresis (CE) method has been developed for the direct separation of the four stereoisomers of a new broad spectrum antifungal agent,…”
Get more information

A decade of innovation in pharmaceutical R&D: the Chorus model by Owens, Paul K., Raddad, Eyas, Miller, Jeffrey W., Stille, John R., Olovich, Kenneth G., Smith, Neil V., Jones, Rosie S., Scherer, Joel C.

“…Chorus is a small, operationally independent organization within Eli Lilly and Company that specializes in drug development from candidate selection through to…”
Get full text

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015: IIS_UK_2015 by Aigbirhio, F. I., Allwein, S., Anwar, A., Atzrodt, J., Audisio, D., Badman, G, Bakale, R., Berthon, F., Bragg, R., Brindle, K. M., Bushby, N., Campos, S., Cant, A. A., Chan, M. Y. T., Colbon, P., Cornelissen, B., Czarny, B., Derdau, V., Dive, V., Dunscombe, M., Eggleston, I., Ellis-Sawyer, K., Elmore, C. S., Engstrom, P., Ericsson, C., Fairlamb, I. J. S., Georgin, D., Godfrey, S. P., He, L., Hickey, M. J., Huscroft, I. T., Kerr, W. J., Lashford, A., Lenz, E., Lewinton, S., L'Hermite, M. M., Lindelöf, Å., Little, G., Lockley, W. J. S., Loreau, O., Maddocks, S., Marguerit, M., Mirabello, V., Mudd, R. J., Nilsson, G. N., Owens, P. K., Pascu, S.I., Patriarche, G., Pimlott, S. L., Pinault, M., Plastow, G., Racys, D. T., Reif, J., Rossi, J., Ruan, J., Sarpaki, S., Sephton, S. M., Simonsson, R., Speed, D. J., Sumal, K., Sutherland, A., Taran, F., Thuleau, A., Wang, Y., Waring, M., Watters, W. H., Wu, J, Xiao, J.

Get full text

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015 by Aigbirhio, F. I., Allwein, S., Anwar, A., Atzrodt, J., Audisio, D., Badman, G, Bakale, R., Berthon, F., Bragg, R., Brindle, K. M., Bushby, N., Campos, S., Cant, A. A., Chan, M. Y. T., Colbon, P., Cornelissen, B., Czarny, B., Derdau, V., Dive, V., Dunscombe, M., Eggleston, I., Ellis-Sawyer, K., Elmore, C. S., Engstrom, P., Ericsson, C., Fairlamb, I. J. S., Georgin, D., Godfrey, S. P., He, L., Hickey, M. J., Huscroft, I. T., Kerr, W. J., Lashford, A., Lenz, E., Lewinton, S., L'Hermite, M. M., Lindelöf, Å., Little, G., Lockley, W. J. S., Loreau, O., Maddocks, S., Marguerit, M., Mirabello, V., Mudd, R. J., Nilsson, G. N., Owens, P. K., Pascu, S.I., Patriarche, G., Pimlott, S. L., Pinault, M., Plastow, G., Racys, D. T., Reif, J., Rossi, J., Ruan, J., Sarpaki, S., Sephton, S. M., Simonsson, R., Speed, D. J., Sumal, K., Sutherland, A., Taran, F., Thuleau, A., Wang, Y., Waring, M., Watters, W. H., Wu, J, Xiao, J.

“…Meeting Summary The 24th annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College,…”
Get full text