Search Results - "Owens, Joshua A"

Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury by Saeedi, Bejan J., Liu, Ken H., Owens, Joshua A., Hunter-Chang, Sarah, Camacho, Mary C., Eboka, Richard U., Chandrasekharan, Bindu, Baker, Nusaiba F., Darby, Trevor M., Robinson, Brian S., Jones, Rheinallt M., Jones, Dean P., Neish, Andrew S.

“…Many studies have suggested a role for gut-resident microbes (the “gut microbiome”) in modulating host health; however, the mechanisms by which they impact…”
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A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring by Barbian, Maria E, Owens, Joshua A, Naudin, Crystal R, Denning, Patricia, Patel, Ravi M, Jones, Rheinallt M

“…The diet during pregnancy, or antenatal diet, influences the offspring's intestinal health. We previously showed that antenatal butyrate supplementation…”
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At the heart of microbial conversations: endocannabinoids and the microbiome in cardiometabolic risk by Khan, Ramsha Nabihah, Maner-Smith, Kristal, A. Owens, Joshua, Barbian, Maria Estefania, Jones, Rheinallt M., R. Naudin, Crystal

“…Cardiometabolic syndrome encompasses intertwined risk factors such as hypertension, dyslipidemia, elevated triglycerides, abdominal obesity, and other…”
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Lactococcus Lactis Subsp. cremoris Is an Efficacious Beneficial Bacterium that Limits Tissue Injury in the Intestine by Darby, Trevor M, Owens, Joshua A, Saeedi, Bejan J, Luo, Liping, Matthews, Jason D, Robinson, Brian S, Naudin, Crystal R, Jones, Rheinallt M

“…The use of beneficial bacteria to promote health is widely practiced. However, experimental evidence corroborating the efficacy of bacteria promoted with such…”
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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression by Tyagi, Abdul Malik, Yu, Mingcan, Darby, Trevor M., Vaccaro, Chiara, Li, Jau-Yi, Owens, Joshua A., Hsu, Emory, Adams, Jonathan, Weitzmann, M. Neale, Jones, Rheinallt M., Pacifici, Roberto

“…Nutritional supplementation with probiotics can prevent pathologic bone loss. Here we examined the impact of supplementation with Lactobacillus rhamnosus GG…”
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Lactococcus lactis Subspecies cremoris Elicits Protection Against Metabolic Changes Induced by a Western-Style Diet by Naudin, Crystal R., Maner-Smith, Kristal, Owens, Joshua A., Wynn, Grace M., Robinson, Brian S., Matthews, Jason D., Reedy, April R., Luo, Liping, Wolfarth, Alexandra A., Darby, Trevor M., Ortlund, Eric A., Jones, Rheinallt M.

“…A Western-style diet, which is high in fat and sugar, can cause significant dyslipidemia and nonalcoholic fatty liver disease; the diet has an especially…”
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Immune Cell Isolation from Murine Intestine for Antibody Array Analysis by Owens, Joshua A, Jones, Rheinallt M

“…Gut mucosal immune cells play an essential role in health due to their ability to orchestrate host signaling events in response to exogenous antigens. These…”
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Butyrate supplementation to pregnant mice elicits cytoprotection against colonic injury in the offspring by Barbian, Maria E., Owens, Joshua A., Naudin, Crystal R., Denning, Patricia W., Patel, Ravi M., Jones, Rheinallt M.

“…Background Maternal diet during pregnancy can impact progeny health and disease by influencing the offspring’s gut microbiome and immune development. Gut…”
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Intracolonic Neuropeptide Y Y1 Receptor Inhibition Attenuates Intestinal Inflammation in Murine Colitis and Cytokine Release in IBD Biopsies by Chandrasekharan, Bindu, Boyer, Darra, Owens, Joshua A, Wolfarth, Alexandra A, Saeedi, Bejan J, Dhere, Tanvi, Iskandar, Heba, Neish, Andrew S

“…Abstract We have demonstrated that neuropeptide Y (NPY) can regulate pro-inflammatory signaling in the gut via cross-talk with the pro-inflammatory cytokine…”
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Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response by Owens, Joshua A., Saeedi, Bejan J., Naudin, Crystal R., Hunter-Chang, Sarah, Barbian, Maria E., Eboka, Richard U., Askew, Lauren, Darby, Trevor M., Robinson, Brian S., Jones, Rheinallt M.

“…In colorectal cancer, approximately 95% of patients are refractory to immunotherapy because of low antitumor immune responses. Therefore, there is an exigent…”
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Neutrophil-Derived Reactive Oxygen Orchestrates Epithelial Cell Signaling Events during Intestinal Repair by Matthews, Jason D., Owens, Joshua A., Naudin, Crystal R., Saeedi, Bejan J., Alam, Ashfaqul, Reedy, April R., Hinrichs, Benjamin H., Sumagin, Ronen, Neish, Andrew S., Jones, Rheinallt M.

“…Recent evidence has demonstrated that reactive oxygen (eg, hydrogen peroxide) can activate host cell signaling pathways that function in repair. We show that…”
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Microbial metabolite delta-valerobetaine is a diet-dependent obesogen by Liu, Ken H., Owens, Joshua A., Saeedi, Bejan, Cohen, Catherine E., Bellissimo, Moriah P., Naudin, Crystal, Darby, Trevor, Druzak, Samuel, Maner-Smith, Kristal, Orr, Michael, Hu, Xin, Fernandes, Jolyn, Camacho, Mary Catherine, Hunter-Chang, Sarah, VanInsberghe, David, Ma, Chunyu, Ganesh, Thota, Yeligar, Samantha M., Uppal, Karan, Go, Young-Mi, Alvarez, Jessica A., Vos, Miriam B., Ziegler, Thomas R., Woodworth, Michael H., Kraft, Colleen S., Jones, Rheinallt M., Ortlund, Eric, Neish, Andrew S., Jones, Dean P.

“…Obesity and obesity-related metabolic disorders are linked to the intestinal microbiome. However, the causality of changes in the microbiome–host interaction…”
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Proline-Rich Acidic Protein 1 (PRAP1) Protects the Gastrointestinal Epithelium From Irradiation-Induced Apoptosis by Wolfarth, Alexandra A., Liu, Xu, Darby, Trevor M., Boyer, Darra J., Spizman, Jocelyn B., Owens, Joshua A., Chandrasekharan, Bindu, Naudin, Crystal R., Hanley, Krisztina Z., Robinson, Brian S., Ortlund, Eric A., Jones, Rheinallt M., Neish, Andrew S.

“…The intestinal epithelium must be resilient to physiochemical stress to uphold the physiological barrier separating the systemic compartment from the microbial…”
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Corrigendum to: Intracolonic Neuropeptide Y Y1 Receptor Inhibition Attenuates Intestinal Inflammation in Murine Colitis and Cytokine Release in IBD Biopsies by Chandrasekharan, Bindu, Boyer, Darra, Owens, Joshua A, Wolfarth, Alexandra A, Saeedi, Bejan J, Dhere, Tanvi, Iskandar, Heba, Neish, Andrew S

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Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune ResponseSummary by Joshua A. Owens, Bejan J. Saeedi, Crystal R. Naudin, Sarah Hunter-Chang, Maria E. Barbian, Richard U. Eboka, Lauren Askew, Trevor M. Darby, Brian S. Robinson, Rheinallt M. Jones, PhD

“…Background & Aims: In colorectal cancer, approximately 95% of patients are refractory to immunotherapy because of low antitumor immune responses. Therefore,…”
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Proline-Rich Acidic Protein 1 (PRAP1) Protects the Gastrointestinal Epithelium From Irradiation-Induced ApoptosisSummary by Alexandra A. Wolfarth, Xu Liu, Trevor M. Darby, Darra J. Boyer, Jocelyn B. Spizman, Joshua A. Owens, Bindu Chandrasekharan, Crystal R. Naudin, Krisztina Z. Hanley, Brian S. Robinson, Eric A. Ortlund, Rheinallt M. Jones, Andrew S. Neish

“…Background & Aims: The intestinal epithelium must be resilient to physiochemical stress to uphold the physiological barrier separating the systemic compartment…”
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