Search Results - "Owens, Gwen E."
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Three-Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells
Published in Angewandte Chemie (International ed.) (01-01-2009)“…A grabby substrate: A 3D nanostructured substrate, namely, a silicon‐nanopillar (SiNP) array coated with epithelial‐cell adhesion‐molecule antibody…”
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Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity
Published in Molecular therapy. Nucleic acids (01-06-2018)“…The CAG repeat expansion that elongates the polyglutamine tract in huntingtin is the root genetic cause of Huntington’s disease (HD), a debilitating…”
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Materials for Controlled Release of Local Anesthetics
Published in ChemMedChem (01-06-2023)“…Controlled release systems for prolonged duration local anesthesia have long been an area of research interest, and now are entering clinical practice, in part…”
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Controlling Anesthesia Hardware With Simple Hand Gestures: Thumbs Up or Thumbs Down?
Published in Anesthesia and analgesia (01-07-2021)“…BACKGROUND:Modern consumer electronic devices and automobiles are often controlled by interfaces that sense physical gestures and spoken commands. In contrast,…”
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Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1
Published in Journal of molecular biology (31-07-2015)“…Huntington's disease is caused by expansion of a polyglutamine (polyQ) repeat in the huntingtin protein. A structural basis for the apparent transition between…”
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The retention of extracellular matrix proteins and angiogenic and mitogenic cytokines in a decellularized porcine dermis
Published in Biomaterials (01-09-2010)“…Abstract Decellularized dermis materials demonstrate considerable utility in surgical procedures including hernia repair and breast reconstruction. A new…”
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Preserved extracellular matrix components and retained biological activity in decellularized porcine mesothelium
Published in Biomaterials (01-09-2010)“…Abstract Mesothelium tissues such as peritoneum and pleura have a thin and strong layer of extracellular matrix that supports mesothelial cells capable of…”
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Decellularized extracellular matrix microparticles as a vehicle for cellular delivery in a model of anastomosis healing
Published in Journal of biomedical materials research. Part A (01-07-2016)“…Extracellular matrix (ECM) materials from animal and human sources have become important materials for soft tissue repair. Microparticles of ECM materials have…”
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Nano "fly paper" technology for the capture of circulating tumor cells
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…Some efficient diagnosis and therapy systems require the isolation and quantification of circulating tumor cells (CTCs), since these species are important…”
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The future of medical diagnostics: large digitized databases
Published in The Yale journal of biology & medicine (25-09-2012)“…The electronic health record mandate within the American Recovery and Reinvestment Act of 2009 will have a far-reaching affect on medicine. In this article, we…”
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A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury
Published in Biomicrofluidics (01-09-2016)“…In pre-clinical safety studies, drug-induced vascular injury (DIVI) is defined as an adverse response to a drug characterized by degenerative and hyperplastic…”
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Comparative analysis of anti-polyglutamine Fab crystals grown on Earth and in microgravity
Published in Acta crystallographica. Section F, Structural biology communications (01-10-2016)“…Huntington's disease is one of nine neurodegenerative diseases caused by a polyglutamine (polyQ)‐repeat expansion. An anti‐polyQ antigen‐binding fragment, MW1…”
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Three-Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells
Published in Angewandte Chemie (09-11-2009)“…Zellfänger: Eine dreidimensionale Nanostruktur aus säulenartig angeordneten Si‐Nanostäben (SiNPs), die mit dem Antikörper anti‐EpCAM (EpCAM:…”
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Three‐Dimensional Nanostructured Substrates toward Efficient Capture of Circulating Tumor Cells
Published in Angewandte Chemie (09-11-2009)Get full text
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