Search Results - "Owens, Gary"
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Vascular Smooth Muscle Cells in Atherosclerosis
Published in Circulation research (19-02-2016)“…The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that aberrant proliferation of VSMCs promotes plaque formation, but that…”
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Simultaneous removal of mixed contaminants, copper and norfloxacin, from aqueous solution by ZIF-8
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-04-2019)“…•ZIF-8 can simultaneously remove 95.4% of Cu and 80.3% of norfloxacin.•Cu removal involved ion exchange with Zn.•Norfloxacin removal involved both…”
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Recent insights into the cellular biology of atherosclerosis
Published in The Journal of cell biology (13-04-2015)“…Atherosclerosis occurs in the subendothelial space (intima) of medium-sized arteries at regions of disturbed blood flow and is triggered by an interplay…”
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Towards sustainable saline agriculture: Interfacial solar evaporation for simultaneous seawater desalination and saline soil remediation
Published in Water research (Oxford) (01-04-2022)“…•An interfacial solar evaporation and planting system was designed.•The evaporator delivered high freshwater production (10.95 kg m−2 day−1).•Solar energy and…”
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Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease
Published in Annual review of physiology (01-01-2012)“…The vascular smooth muscle cell (SMC) in adult animals is a highly specialized cell whose principal function is contraction. However, this cell displays…”
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Smooth muscle cell phenotypic switching in atherosclerosis
Published in Cardiovascular research (15-07-2012)“…Smooth muscle cells (SMCs) possess remarkable phenotypic plasticity that allows rapid adaptation to fluctuating environmental cues, including during…”
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A photothermal reservoir for highly efficient solar steam generation without bulk water
Published in Science bulletin (Beijing) (15-11-2019)“…A photothermal reservoir composed of a water storage core encapsulated by a graphene-based aerogel sheet is designed for solar-steam generation without bulk…”
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Epigenetic Control of Smooth Muscle Cell Identity and Lineage Memory
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2015)“…Vascular smooth muscle cells (SMCs), like all cells, acquire a cell-specific epigenetic signature during development that includes acquisition of a unique…”
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A flexible photothermal cotton-CuS nanocage-agarose aerogel towards portable solar steam generation
Published in Nano energy (01-02-2019)“…Solar-steam generation provides an economically efficient pathway to produce clean water by using solar irradiation as an energy source. While this strategy is…”
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KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
Published in Nature medicine (01-06-2015)“…A high percentage of smooth muscle cells in atherosclerotic lesions lose expression of smooth muscle marker proteins and acquire the phenotype of other cell…”
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Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis
Published in Circulation (New York, N.Y.) (24-11-2020)“…Rupture and erosion of advanced atherosclerotic lesions with a resultant myocardial infarction or stroke are the leading worldwide cause of death. However, we…”
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Detection of histone modifications at specific gene loci in single cells in histological sections
Published in Nature methods (01-02-2013)“…A combination of in situ hybridization and a proximity ligation assay allows the visualization of histone modifications at single genomic loci with single-cell…”
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The CANTOS Trial: One Important Step for Clinical Cardiology but a Giant Leap for Vascular Biology
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-2017)“…The results of the CANTOS trial provide exciting evidence in support of the inflammatory hypothesis of atherosclerosis in humans, and is the first phase III…”
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Cooperative Binding of KLF4, pELK-1, and HDAC2 to a G/C Repressor Element in the SM22α Promoter Mediates Transcriptional Silencing During SMC Phenotypic Switching In Vivo
Published in Circulation research (31-08-2012)“…RATIONALE:We previously identified conserved G/C Repressor elements in the promoters of most smooth muscle cell (SMC) marker genes and demonstrated that…”
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Reconciling Smooth Muscle Cell Oligoclonality and Proliferative Capacity in Experimental Atherosclerosis
Published in Circulation research (09-12-2016)Get full text
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Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells
Published in American Journal of Physiology: Cell Physiology (01-01-2007)“…Smooth muscle cell (SMC) differentiation is an essential component of vascular development and these cells perform biosynthetic, proliferative, and contractile…”
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The Importance of Addressing Depression and Diabetes Distress in Adults with Type 2 Diabetes
Published in Journal of general internal medicine : JGIM (01-02-2019)“…People with type 2 diabetes often experience two common mental health conditions: depression and diabetes distress. Both increase a patient’s risk for…”
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Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice
Published in Nature medicine (01-09-2018)“…Despite decades of research, our understanding of the processes controlling late-stage atherosclerotic plaque stability remains poor. A prevailing hypothesis…”
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Anode modification by biogenic gold nanoparticles for the improved performance of microbial fuel cells and microbial community shift
Published in Bioresource technology (01-12-2018)“…•BioAu modification significantly improved the electricity generation of MFCs.•Better performance was achieved with BioAu/MWCNT nanohybrids as the…”
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