Search Results - "Owens, D R"

Stepwise intensification of insulin therapy in Type 2 diabetes management-exploring the concept of the basal-plus approach in clinical practice by Owens, D. R.

“…Basal insulin provides an effective method for initiating insulin therapy in people with Type 2 diabetes, resulting in significant improvements in glycaemic…”
Get full text

Efficacy and safety of linagliptin in persons with Type 2 diabetes inadequately controlled by a combination of metformin and sulphonylurea: a 24-week randomized study by Owens, D. R., Swallow, R., Dugi, K. A., Woerle, H. J.

“…To examine the efficacy and safety of the dipeptidyl peptidase-4 inhibitor linagliptin in persons with Type 2 diabetes mellitus inadequately controlled…”
Get full text

Glucocentric risk factors for macrovascular complications in diabetes: Glucose ‘legacy’ and ‘variability’-what we see, know and try to comprehend by Monnier, L., Colette, C., Schlienger, J.-L., Bauduceau, B., R Owens, D.

“…Recognizing the role of dysglycaemia, ‘ambient’ hyperglycaemia, ‘metabolic memory’ and glycaemic variability as risk factors for macrovascular diseases is…”
Get full text

Alternative routes of insulin delivery by Owens, D. R., Zinman, B., Bolli, G.

“…Attempts at replicating physiological insulin secretion, as a means of restoring the normal metabolic milieu and thereby minimizing the risk of diabetic…”
Get full text

Regulation of oxidative stress by glycaemic control: evidence for an independent inhibitory effect of insulin therapy by Monnier, L, Colette, C, Mas, E, Michel, F, Cristol, J. P, Boegner, C, Owens, D. R

“…Aims/hypothesis We examined whether type of diabetes and/or insulin treatment can modulate the impact of sustained hyperglycaemia and glycaemic variability as…”
Get full text

Lixisenatide, a novel GLP-1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitus by Bolli, G. B., Owens, D. R.

“…Recent advances in therapies for the treatment of type 2 diabetes mellitus (T2DM) have led to the development of glucagon‐like peptide‐1 receptor agonists…”
Get full text

Differential effects of GLP-1 receptor agonists on components of dysglycaemia in individuals with type 2 diabetes mellitus by Owens, D.R, Monnier, L, Bolli, G.B

“…Abstract Metabolic consequences of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are the result of enhanced glucose-stimulated insulin secretion,…”
Get full text

Effects of initiation and titration of a single pre-prandial dose of insulin glulisine while continuing titrated insulin glargine in type 2 diabetes: a 6-month 'proof-of-concept' study by Owens, D. R., Luzio, S. D., Sert-Langeron, C., Riddle, M. C.

“…Aim: Stepwise intensification of insulin treatment to match the progressive decline of endogenous insulin secretion has been shown to be an effective…”
Get full text

Prevalence of diabetic macular oedema and related health and social care resource use in England by Minassian, D C, Owens, D R, Reidy, A

“…To address the absence from the public health ophthalmology literature of age- and sex-specific prevalence and related resource use for diabetic macular oedema…”
Get more information

IDF Diabetes Atlas: A review of studies utilising retinal photography on the global prevalence of diabetes related retinopathy between 2015 and 2018 by Thomas, R.L., Halim, S., Gurudas, S., Sivaprasad, S., Owens, D.R.

“…The purpose of this study is to assess the prevalence of diabetic retinopathy (DR) world-wide from articles published since 2015 where the assessment of the…”
Get full text

Does Feeding by Halyomorpha halys (Hemiptera: Pentatomidae) Reduce Soybean Seed Quality and Yield? by Owens, D. R, Herbert, Jr, D. A, Dively, G. P, Reisig, D. D, Kuhar, T. P

“…The nonnative brown marmorated stink bug, Halyomorpha halys Stål (Hemiptera: Pentatomidae), has become an abundant pest of mid-Atlantic soybean since its…”
Get full text

Near normal HbA1c with stable glucose homeostasis: the ultimate target/aim of diabetes therapy by Monnier, L., Colette, C., Dejager, S., Owens, D. R.

“…Achieving near normal glucose homeostasis implies that all components of dysglycemia that are present in diabetes states be eliminated. Reducing…”
Get full text

Estimates of the relative and absolute diurnal contributions of fasting and post-prandial plasma glucose over a range of hyperglycaemia in type 2 diabetes by Peter, R, Dunseath, G, Luzio, S.D, Owens, D.R

“…Abstract Aims To re-examine the relative and absolute contributions of fasting/pre-prandial glucose (FPG) and post-prandial glucose (PPG) to 24-h…”
Get full text

Paediatric nutrition risk scores in clinical practice: children with inflammatory bowel disease by Wiskin, A. E., Owens, D. R., Cornelius, V. R., Wootton, S. A., Beattie, R. M.

“…How to cite this article 
Wiskin A.E., Owens D.R., Cornelius V.R., Wootton S.A. & Beattie R.M. (2012) Paediatric nutrition risk scores in clinical practice:…”
Get full text

Comparison of the pharmacokinetics and pharmacodynamics of biphasic insulin aspart and insulin glargine in people with type 2 diabetes by LUZIO, S, DUNSEATH, G, PETER, R, PAUVADAY, V, OWENS, D. R

“…The pharmacokinetic and pharmacodynamic properties of biphasic insulin aspart (BIAsp 30) (30% soluble, 70% protaminated insulin aspart [IAsp]) and insulin…”
Get full text

Preferences of people with diabetes for diabetic retinopathy screening: a discrete choice experiment by Yeo, S. T., Edwards, R. T., Fargher, E. A., Luzio, S. D., Thomas, R. L., Owens, D. R.

“…Diabet. Med. 29, 869–877 (2012) Aims  The ever‐increasing prevalence of diabetes places pressure on the provision of diabetic retinopathy screening services…”
Get full text

Use of cystatin C-based estimations of glomerular filtration rate in patients with type 2 diabetes by Chudleigh, R. A, Ollerton, R. L, Dunseath, G, Peter, R, Harvey, J. N, Luzio, S, Owens, D. R

“…Aims/hypothesis The Modification of Diet in Renal Disease (MDRD) equation has recognised limitations when using estimated GFR in persons at risk of chronic…”
Get full text

Daytime variability of postprandial glucose tolerance and pancreatic B-cell function using 12-h profiles in persons with Type 2 diabetes by Peter, R., Dunseath, G., Luzio, S. D., Chudleigh, R., Roy Choudhury, S., Owens, D. R.

“…Diabet. Med. 27, 266–273 (2010) Aims  To study the variation in daytime glucose tolerance and pancreatic B‐cell function at different levels of glycated…”
Get full text

Insulin resistance and inflammation - A further systemic complication of COPD by Bolton, C E, Evans, M, Ionescu, A A, Edwards, S M, Morris, R H K, Dunseath, G, Luzio, S D, Owens, D R, Shale, D J

“…Chronic obstructive pulmonary disease (COPD) is associated with a continuous systemic inflammatory response. Furthermore, COPD is associated with an excess…”
Get more information

A comparison of the pharmacodynamic profiles of insulin detemir and insulin glargine: A single dose clamp study in people with type 2 diabetes by Luzio, S.D, Dunseath, G.J, Atkinson, M.D, Owens, D.R

“…Abstract Aim The pharmacodynamic properties of a single dose of 0.5 U/kg insulin detemir and insulin glargine were compared during two 24-h isoglycaemic…”
Get full text