Search Results - "Owens, Brian S."

Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S 2 pocket by Reiter, Lawrence A., Rizzi, James P., Pandit, Jayvardan, Lasut, Michael J., McGahee, Shunda M., Parikh, Vinod D., Blake, James F., Danley, Dennis E., Laird, Ellen R., Lopez-Anaya, Arturo, Lopresti-Morrow, Lori L., Mansour, Mahmoud N., Martinelli, Gary J., Mitchell, Peter G., Owens, Brian S., Pauly, Thomas A., Reeves, Lisa M., Schulte, Gayle K., Yocum, Sue A.

“…Through the use of empirical and computational methods, phosphinate-based inhibitors of MMP-1 and MMP-13 that bind into the S 2 pocket of these enzymes were…”
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Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket by REITER, L. A, RIZZI, J. P, LOPRESTI-MORROW, L. L, MANSOUR, M. N, MARTINELLI, G. J, MITCHELL, P. G, OWENS, B. S, PAULY, T. A, REEVES, L. M, SCHULTE, G. K, YOCUM, S. A, PANDIT, J, LASUT, M. J, MCGAHEE, S. M, PARIKH, V. D, BLAKE, J. F, DANLEY, D. E, LAIRD, E. R, LOPEZ-ANAYA, A

“…Through the use of empirical and computational methods, phosphinate-based inhibitors of MMP-1 and MMP-13 that bind into the S2 pocket of these enzymes were…”
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N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D 4 by Brown, Matthew F., Marfat, Anthony, Antognoli, Gerard, Chambers, Robert J., Cheng, John B., Damon, David B., Liston, Theodore E., McGlynn, Molly A., O'Sullivan, Stacie P., Owens, Brian S., Pillar, Joann S., Shirley, John T., Watson, John W.

“…Exploration of the indole nitrogen region of Zafirlukast ( 1) has uncovered a potent series of cysteinyl leukotriene D 4 (LTD 4) antagonists. These studies…”
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N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D4 by BROWN, M. F, MARFAT, A, PILLAR, J. S, SHIRLEY, J. T, WATSON, J. W, ANTOGNOLI, G, CHAMBERS, R. J, CHENG, J. B, DAMON, D. B, LISTON, T. E, MCGLYNN, M. A, O'SULLIVAN, S. P, OWENS, B. S

“…Exploration of the indole nitrogen region of Zafirlukast (1) has uncovered a potent series of cysteinyl leukotriene D4 (LTD4) antagonists. These studies showed…”
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