Search Results - "Owen, Rhiannon"

MetaInsight: An interactive web‐based tool for analyzing, interrogating, and visualizing network meta‐analyses using R‐shiny and netmeta by Owen, Rhiannon K., Bradbury, Naomi, Xin, Yiqiao, Cooper, Nicola, Sutton, Alex

“…Background Network meta‐analysis (NMA) is a powerful analysis method used to identify the best treatments for a condition and is used extensively by health…”
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Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making by Owen, Rhiannon K., Cooper, Nicola J., Quinn, Terence J., Lees, Rosalind, Sutton, Alex J.

“…Network meta-analyses (NMA) have extensively been used to compare the effectiveness of multiple interventions for health care policy and decision-making…”
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Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records by Owen, Rhiannon K, Conroy, Simon P, Taub, Nicholas, Jones, Will, Bryden, Daniele, Pareek, Manish, Faull, Christina, Abrams, Keith R, Davis, Daniel, Banerjee, Jay

“…Abstract Background The aim of this study was to describe outcomes in hospitalised older people with different levels of frailty and COVID-19 infection…”
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Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales by Agrawal, Utkarsh, Bedston, Stuart, McCowan, Colin, Oke, Jason, Patterson, Lynsey, Robertson, Chris, Akbari, Ashley, Azcoaga-Lorenzo, Amaya, Bradley, Declan T, Fagbamigbe, Adeniyi Francis, Grange, Zoe, Hall, Elliott C R, Joy, Mark, Katikireddi, Srinivasa Vittal, Kerr, Steven, Ritchie, Lewis, Murphy, Siobhán, Owen, Rhiannon K, Rudan, Igor, Shah, Syed Ahmar, Simpson, Colin R, Torabi, Fatemeh, Tsang, Ruby S M, de Lusignan, Simon, Lyons, Ronan A, O'Reilly, Dermot, Sheikh, Aziz

“…Current UK vaccination policy is to offer future COVID-19 booster doses to individuals at high risk of serious illness from COVID-19, but it is still uncertain…”
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First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales by Kerr, Steven, Joy, Mark, Torabi, Fatemeh, Bedston, Stuart, Akbari, Ashley, Agrawal, Utkarsh, Beggs, Jillian, Bradley, Declan, Chuter, Antony, Docherty, Annemarie B, Ford, David, Hobbs, Richard, Katikireddi, Srinivasa Vittal, Lowthian, Emily, de Lusignan, Simon, Lyons, Ronan, Marple, James, McCowan, Colin, McGagh, Dylan, McMenamin, Jim, Moore, Emily, Murray, Josephine-L K, Owen, Rhiannon K, Pan, Jiafeng, Ritchie, Lewis, Shah, Syed Ahmar, Shi, Ting, Stock, Sarah, Tsang, Ruby S M, Vasileiou, Eleftheria, Woolhouse, Mark, Simpson, Colin R, Robertson, Chris, Sheikh, Aziz

“…Several countries restricted the administration of ChAdOx1 to older age groups in 2021 over safety concerns following case reports and observed versus expected…”
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Uptake of COVID-19 vaccinations amongst 3,433,483 children and young people: meta-analysis of UK prospective cohorts by Aldridge, Sarah J., Agrawal, Utkarsh, Murphy, Siobhán, Millington, Tristan, Akbari, Ashley, Almaghrabi, Fatima, Anand, Sneha N., Bedston, Stuart, Goudie, Rosalind, Griffiths, Rowena, Joy, Mark, Lowthian, Emily, de Lusignan, Simon, Patterson, Lynsey, Robertson, Chris, Rudan, Igor, Bradley, Declan T., Lyons, Ronan A., Sheikh, Aziz, Owen, Rhiannon K.

“…SARS-CoV-2 infection in children and young people (CYP) can lead to life-threatening COVID-19, transmission within households and schools, and the development…”
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Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis by Umemneku-Chikere, Chinyereugo M, Wheaton, Lorna, Poad, Heather, Ray, Devleena, Andrade, Ilse Cuevas, Khan, Sam, Tappenden, Paul, Abrams, Keith R, Owen, Rhiannon K, Bujkiewicz, Sylwia

“…We aimed to develop a network meta-analytic model for the evaluation of treatment effectiveness within predictive biomarker subgroups, by combining evidence…”
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Network Meta-Analysis: Development of a Three-Level Hierarchical Modeling Approach Incorporating Dose-Related Constraints by Owen, Rhiannon K., BSc, MSc, Tincello, Douglas G., BSc, MBChB, MD, FRCOG, Keith, R. Abrams, PhD, CStat

“…Abstract Background Network meta-analysis (NMA) is commonly used in evidence synthesis; however, in situations in which there are a large number of treatment…”
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COVID-19 vaccine uptake, effectiveness, and waning in 82,959 health care workers: A national prospective cohort study in Wales by Bedston, Stuart, Akbari, Ashley, Jarvis, Christopher I., Lowthian, Emily, Torabi, Fatemeh, North, Laura, Lyons, Jane, Perry, Malorie, Griffiths, Lucy J., Owen, Rhiannon K., Beggs, Jillian, Chuter, Antony, Bradley, Declan T., de Lusignan, Simon, Fry, Richard, Richard Hobbs, F.D., Hollinghurst, Joe, Katikireddi, Srinivasa Vittal, Murphy, Siobhán, O'Reily, Dermot, Robertson, Chris, Shi, Ting, Tsang, Ruby S.M., Sheikh, Aziz, Lyons, Ronan A.

“…•90% vaccine uptake by 30 Sept 2021, but uptake in more deprived areas was lower.•BNT162b2 was 85% effective after 2 weeks from second dose and 52% from…”
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Multivariate network meta-analysis incorporating class effects by Owen, Rhiannon K, Bujkiewicz, Sylwia, Tincello, Douglas G, Abrams, Keith R

“…Network meta-analysis synthesises data from a number of clinical trials in order to assess the comparative efficacy of multiple healthcare interventions in…”
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Understanding medicine related adverse events in people with multiple long-term conditions and polypharmacy by Rafferty, James, Lyons, Jane, Lyons, Ronan, Owen, Rhiannon

“…Background and ObjectivesPolypharmacy is increasingly common in people living with multiple long-term conditions (MLTC), but clinical evidence often does not…”
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Modelling the joint accuracy of two diagnostic tests using evidence synthesis methods incorporating linked electronic health records by Sheppard, Athena, Quinn, Terry, Bujkiewicz, Sylwia, Owen, Rhiannon

“…Background and ObjectivesTo compare the accuracy of different diagnostic pathways comprising of multiple diagnostic tests, statistical methods that evaluate…”
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Risk of thrombocytopenic, haemorrhagic and thromboembolic disorders following COVID-19 vaccination and positive test: a self-controlled case series analysis in Wales by Torabi, Fatemeh, Bedston, Stuart, Lowthian, Emily, Akbari, Ashley, Owen, Rhiannon K., Bradley, Declan T., Agrawal, Utkarsh, Collins, Peter, Fry, Richard, Griffiths, Lucy J., Beggs, Jillian, Davies, Gareth, Hollinghurst, Joe, Lyons, Jane, Abbasizanjani, Hoda, Cottrell, Simon, Perry, Malorie, Roberts, Richard, Azcoaga-Lorenzo, Amaya, Fagbamigbe, Adeniyi Francis, Shi, Ting, Tsang, Ruby S. M., Robertson, Chris, Hobbs, F. D. Richard, de Lusignan, Simon, McCowan, Colin, Gravenor, Michael, Simpson, Colin R., Sheikh, Aziz, Lyons, Ronan A.

“…There is a need for better understanding of the risk of thrombocytopenic, haemorrhagic, thromboembolic disorders following first, second and booster…”
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Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland by Fagbamigbe, Adeniyi Francis, Agrawal, Utkarsh, Azcoaga-Lorenzo, Amaya, MacKerron, Briana, Özyiğit, Eda Bilici, Alexander, Daniel C, Akbari, Ashley, Owen, Rhiannon K, Lyons, Jane, Lyons, Ronan A, Denaxas, Spiros, Kirk, Paul, Miller, Ana Corina, Harper, Gill, Dezateux, Carol, Brookes, Anthony, Richardson, Sylvia, Nirantharakumar, Krishnarajah, Guthrie, Bruce, Hughes, Lloyd, Kadam, Umesh T, Khunti, Kamlesh, Abrams, Keith R, McCowan, Colin

“…There is still limited understanding of how chronic conditions co-occur in patients with multimorbidity and what are the consequences for patients and the…”
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Exploring ethnicity dynamics in Wales: a longitudinal population-scale linked data study and development of a harmonised ethnicity spine by Akbari, Ashley, Torabi, Fatemeh, Bedston, Stuart, Lowthian, Emily, Abbasizanjani, Hoda, Fry, Richard, Lyons, Jane, Owen, Rhiannon K, Khunti, Kamlesh, Lyons, Ronan

“…ObjectiveThis study aims to create a national ethnicity spine based on all available ethnicity records in linkable anonymised electronic health record and…”
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COVID-19 booster vaccination uptake and infection breakthrough amongst health care workers in Wales: A national prospective cohort study by Bedston, Stuart, Lowthian, Emily, Jarvis, Christopher I., Akbari, Ashley, Beggs, Jillian, Bradley, Declan, de Lusignan, Simon, Griffiths, Rowena, Herbert, Laura, Hobbs, Richard, Kerr, Steven, Lyons, Jane, Midgley, William, Owen, Rhiannon K., Quint, Jennifer K., Tsang, Ruby, Torabi, Fatemeh, Sheikh, Aziz, Lyons, Ronan A.

“…•Overall, booster uptake was at 91% by 29th February 2022.•Uptake lower in more deprived areas and the Black ethnic group.•Booster uptake comparable to first…”
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The Hospital Frailty Risk Score (HFRS) applied to primary data: protocol for a systematic review by Alshibani, Abdullah, Warner, Bronwen, Owen, Rhiannon K, Mukherjee, Abir, Gilbert, Thomas, Conroy, Simon

“…IntroductionFrailty is characterised by vulnerability to adverse health outcomes and increases with age. Many frailty risk scores have been developed. One…”
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Variations in COVID-19 vaccination uptake among people in receipt of psychotropic drugs: cross-sectional analysis of a national population-based prospective cohort by Murphy, Siobhán, O'Reilly, Dermot, Owen, Rhiannon K., Akbari, Ashley, Lowthian, Emily, Bedston, Stuart, Torabi, Fatemeh, Beggs, Jillian, Chuter, Antony, de Lusignan, Simon, Hobbs, Richard, Robertson, Chris, Katikireddi, Srinivasa Vittal, Sheikh, Aziz, Bradley, Declan T.

“…Coronavirus disease 2019 (COVID-19) has disproportionately affected people with mental health conditions. We investigated the association between receiving…”
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Applying Trial Emulation Methods to Population-Scale Linked Electronic Health Records for Individuals with Multiple Long-Term Conditions Whilst Adjusting for Informative Observations by Abrams, Keith, Rafferty, James, Lyons, Jane, Lyons, Ronan, Owen, Rhiannon

“…Background & ObjectivesTrial Emulation methods can be applied to Population-Scale Linked Electronic Health Records (EHR) to generalise the results of…”
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Modelling The Effects of Multi-Indication Treatment for Multiple Long-Term Conditions Using Population-Scale Linked Electronic Health Records To Inform Healthcare Policy by Owen, Rhiannon, Rafferty, James, Lyons, Jane, Lyons, Ronan, Abrams, Keith

“…Background and ObjectivesHealthcare decision-making has previously focused on developing recommendations for single conditions. This research aimed to develop…”
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