Search Results - "Owen, A."

Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model by Zhang, Yan, Tan, Hui, Daniels, Jacob D, Zandkarimi, Fereshteh, Liu, Hengrui, Brown, Lewis M, Uchida, Koji, O'Connor, Owen A, Stockwell, Brent R

“…Ferroptosis is a form of regulated cell death that can be induced by inhibition of the cystine-glutamate antiporter, system x . Among the existing system x…”
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The rapidly changing landscape in mature T‐cell lymphoma (MTCL) biology and management by Marchi, Enrica, O’Connor, Owen A.

“…Historical advances in the care of patients with non‐Hodgkin lymphoma (NHL) have been restricted largely to patients with B‐cell lymphoma. The peripheral…”
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Association of Depression and Anxiety With Cognitive Impairment 6 Months After Stroke by Williams, Owen A., Demeyere, Nele

“…To investigate the associations between general cognitive impairment and domain-specific cognitive impairment with depression and anxiety at 6 months…”
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Brentuximab vedotin plus bendamustine: a highly active first salvage regimen for relapsed or refractory Hodgkin lymphoma by LaCasce, Ann S., Bociek, R. Gregory, Sawas, Ahmed, Caimi, Paolo, Agura, Edward, Matous, Jeffrey, Ansell, Stephen M., Crosswell, Howland E., Islas-Ohlmayer, Miguel, Behler, Caroline, Cheung, Eric, Forero-Torres, Andres, Vose, Julie, O'Connor, Owen A., Josephson, Neil, Wang, Yinghui, Advani, Ranjana

“…Autologous stem cell transplantation (ASCT) is standard of care for patients with Hodgkin lymphoma (HL) who have relapsed/refractory disease after frontline…”
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Neuropathology and molecular diagnosis of Synucleinopathies by Koga, Shunsuke, Sekiya, Hiroaki, Kondru, Naveen, Ross, Owen A, Dickson, Dennis W

“…Synucleinopathies are clinically and pathologically heterogeneous disorders characterized by pathologic aggregates of α-synuclein in neurons and glia, in the…”
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TFEB and TFE3 are novel components of the integrated stress response by Martina, José A, Diab, Heba I, Brady, Owen A, Puertollano, Rosa

“…To reestablish homeostasis and mitigate stress, cells must activate a series of adaptive intracellular signaling pathways. The participation of the…”
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Phthalocyanine-Based Organic Thin-Film Transistors: A Review of Recent Advances by Melville, Owen A, Lessard, Benoît H, Bender, Timothy P

“…Metal phthalocyanines (MPcs) are versatile conjugated macrocycles that have attracted a great deal of interest as active components in modern organic…”
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Final results of a phase 1 study of loncastuximab tesirine in relapsed/refractory B-cell non-Hodgkin lymphoma by Hamadani, Mehdi, Radford, John, Carlo-Stella, Carmelo, Caimi, Paolo F., Reid, Erin, O'Connor, Owen A., Feingold, Jay M., Ardeshna, Kirit M., Townsend, William, Solh, Melhem, Heffner, Leonard T., Ungar, David, Wang, Luqiang, Boni, Joseph, Havenith, Karin, Qin, Yajuan, Kahl, Brad S.

“…The prognosis for patients with relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) remains poor, with a need for alternatives to current salvage…”
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Nature and timing of Quaternary glaciation in the Himalayan–Tibetan orogen by Owen, Lewis A., Dortch, Jason M.

“…Much effort has been made in recent years to define the timing and extent of Quaternary glaciation throughout the Himalayan–Tibetan orogen. These studies are…”
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Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity by Wilson, Wyndham H, Prof, O'Connor, Owen A, Prof, Czuczman, Myron S, Prof, LaCasce, Ann S, MD, Gerecitano, John F, MD, Leonard, John P, Prof, Tulpule, Anil, MD, Dunleavy, Kieron, MD, Xiong, Hao, PhD, Chiu, Yi-Lin, PhD, Cui, Yue, PhD, Busman, Todd, MS, Elmore, Steven W, PhD, Rosenberg, Saul H, PhD, Krivoshik, Andrew P, MD, Enschede, Sari H, MD, Humerickhouse, Rod A, MD

“…Summary Background Proteins of the BCL-2 family regulate clonal selection and survival of lymphocytes, and are frequently overexpressed in lymphomas…”
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Towards Better Breast Cancer Outcomes for Indigenous Populations in High-Income Countries with Highly Developed Health Systems by Ung, Owen A.

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Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal Chemistry by Bull, James A, Croft, Rosemary A, Davis, Owen A, Doran, Robert, Morgan, Kate F

“…The four-membered oxetane ring has been increasingly exploited for its contrasting behaviors: its influence on physicochemical properties as a stable motif in…”
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Functional Electrical Stimulation Improves Activity After Stroke: A Systematic Review With Meta-Analysis by Howlett, Owen A., MaOT, Lannin, Natasha A., PhD, Ada, Louise, PhD, McKinstry, Carol, PhD

“…Abstract Objective To investigate the effect of functional electrical stimulation (FES) in improving activity and to investigate whether FES is more effective…”
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Latest Pleistocene and Holocene glacier fluctuations in the Himalaya and Tibet by Owen, Lewis A.

“…The timing and extent of latest Pleistocene and Holocene alpine glacier fluctuations in the Himalaya and Tibet are poorly defined due to the logistical and…”
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Human consciousness is supported by dynamic complex patterns of brain signal coordination by Demertzi, A, Tagliazucchi, E, Dehaene, S, Deco, G, Barttfeld, P, Raimondo, F, Martial, C, Fernández-Espejo, D, Rohaut, B, Voss, H U, Schiff, N D, Owen, A M, Laureys, S, Naccache, L, Sitt, J D

“…Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and…”
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Brentuximab Vedotin by Deng, Changchun, Pan, Beiqing, O'Connor, Owen A

“…Brentuximab vedotin (SGN-35), an intravenously administered CD30-specific antibody-drug conjugate, has recently been approved by the U.S. Food and Drug…”
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Combined oral 5-azacytidine and romidepsin are highly effective in patients with PTCL: a multicenter phase 2 study by Falchi, Lorenzo, Ma, Helen, Klein, Sandra, Lue, Jennifer K., Montanari, Francesca, Marchi, Enrica, Deng, Changchun, Kim, Hye A., Rada, Aishling, Jacob, Alice T., Kinahan, Cristina, Francescone, Mark M., Soderquist, Craig R., Park, David C., Bhagat, Govind, Nandakumar, Renu, Menezes, Daniel, Scotto, Luigi, Sokol, Lubomir, Shustov, Andrei R., O'Connor, Owen A.

“…Peripheral T-cell lymphomas (PTCLs) are uniquely vulnerable to epigenetic modifiers. We demonstrated in vitro synergism between histone deacetylase inhibitors…”
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A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome by Anderson, Owen A, Finkelstein, Arthur, Shima, David T

“…With ageing extracellular material is deposited in Bruch's membrane, as drusen. Lipofuscin is deposited in retinal pigment epithelial cells. Both of these…”
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HX009, a novel BsAb dual targeting PD1 x CD47, demonstrates potent anti-lymphoma activity in preclinical models by Ke, Hang, Zhang, Faming, Wang, Jingjing, Xiong, Lingxin, An, Xiaoyu, Tu, Xiaolong, Chen, Cen, Wang, Yueying, Mao, Binchen, Guo, Sheng, Ju, Cunxiang, He, Xiangfei, Sun, Ruilin, Zhang, Lei, O’Connor, Owen A., Li, Qi-Xiang

“…Both PD1/PD-L1 and CD47 blockades have demonstrated limited activity in most subtypes of NHL save NK/T-cell lymphoma. The hemotoxicity with anti-CD47 agents in…”
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Regio- and Stereospecific Synthesis of C‑3 Functionalized Proline Derivatives by Palladium Catalyzed Directed C(sp3)–H Arylation by Affron, Dominic P, Davis, Owen A, Bull, James A

“…Functionalization of C­(sp3)–H bonds at the unactivated 3-position of proline derivatives has been achieved using aryl iodides and palladium catalysis. This…”
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