Search Results - "Owczarek, Ewelina P"
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Proteomic Analyses Reveal the Role of Alpha-2-Macroglobulin in Canine Osteosarcoma Cell Migration
Published in International journal of molecular sciences (01-04-2024)“…Canine osteosarcoma (OSA) is an aggressive bone neoplasia with high metastatic potential. Metastasis is the main cause of death associated with OSA, and there…”
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Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system
Published in PloS one (28-03-2018)“…Deciphering a function of a given protein requires investigating various biological aspects. Usually, the protein of interest is expressed with a fusion tag…”
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Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings
Published in iScience (24-09-2021)“…Processive exoribonucleases are executors of RNA decay. In humans, their physical but not functional interactions were thoughtfully investigated. Here we have…”
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Two novel C-terminal frameshift mutations in the β-globin gene lead to rapid mRNA decay
Published in BMC medical genetics (08-06-2017)“…The thalassemia syndromes are classified according to the globin chain or chains whose production is affected. β-thalassemias are caused by point mutations or,…”
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Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target
Published in Nucleic acids research (01-01-2014)“…hDIS3 is a mainly nuclear, catalytic subunit of the human exosome complex, containing exonucleolytic (RNB) and endonucleolytic (PIN) active domains. Mutations…”
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Two novel C-terminal frameshift mutations in the [beta]-globin gene lead to rapid mRNA decay
Published in BMC medical genetics (08-06-2017)“…The thalassemia syndromes are classified according to the globin chain or chains whose production is affected. [beta]-thalassemias are caused by point…”
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