Search Results - "Ovize, M."

Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D by Bochaton, T, Crola-Da-Silva, C, Pillot, B, Villedieu, C, Ferreras, L, Alam, M.R, Thibault, H, Strina, M, Gharib, A, Ovize, M, Baetz, D

“…Abstract Rationale . How ischemic postconditioning can inhibit opening of the mitochondrial permeability transition pore (PTP) and subsequent cardiac myocytes…”
Get full text

9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection by Bell, R. M., Bøtker, H. E., Carr, R. D., Davidson, S. M., Downey, J. M., Dutka, D. P., Heusch, G., Ibanez, B., Macallister, R., Stoppe, C., Ovize, M., Redington, A., Walker, J. M., Yellon, D. M.

“…In the 30 years since the original description of ischaemic preconditioning, understanding of the pathophysiology of ischaemia/reperfusion injury and concepts…”
Get full text

Remote ischaemic conditioning: defining critical criteria for success—report from the 11th Hatter Cardiovascular Workshop by Bell, R. M., Basalay, M., Bøtker, H. E., Beikoghli Kalkhoran, S., Carr, R. D., Cunningham, J., Davidson, S. M., England, T. J., Giesz, S., Ghosh, A. K., Golforoush, P., Gourine, A. V., Hausenloy, D. J., Heusch, G., Ibanez, B., Kleinbongard, P., Lecour, S., Lukhna, K., Ntsekhe, M., Ovize, M., Salama, A. D., Vilahur, G., Walker, J. M., Yellon, D. M.

“…The Hatter Cardiovascular Institute biennial workshop, originally scheduled for April 2020 but postponed for 2 years due to the Covid pandemic, was organised…”
Get full text

The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury by Gomez, L, Thiebaut, P-A, Paillard, M, Ducreux, S, Abrial, M, Crola Da Silva, C, Durand, A, Alam, M R, Van Coppenolle, F, Sheu, S-S, Ovize, M

“…Glycogen synthase kinase-3 β (GSK3 β ) is a multifunctional kinase whose inhibition is known to limit myocardial ischemia–reperfusion injury. However, the…”
Get full text

Postconditioning and protection from reperfusion injury: where do we stand?Position Paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology by Ovize, Michel, Baxter, Gary F., Di Lisa, Fabio, Ferdinandy, Péter, Garcia-Dorado, David, Hausenloy, Derek J., Heusch, Gerd, Vinten-Johansen, Jakob, Yellon, Derek M., Schulz, Rainer

“…Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of reflow applied at the onset of reperfusion following sustained…”
Get full text

The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca2+ flux from the endoplasmic reticulum to mitochondria by Fouqué, A, Lepvrier, E, Debure, L, Gouriou, Y, Malleter, M, Delcroix, V, Ovize, M, Ducret, T, Li, C, Hammadi, M, Vacher, P, Legembre, P

“…Metalloprotease-processed CD95L (cl-CD95L) is a soluble cytokine that implements a PI3K/Ca 2+ signaling pathway in triple-negative breast cancer (TNBC) cells…”
Get full text

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies by Lecour, Sandrine, Bøtker, Hans E, Condorelli, Gianluigi, Davidson, Sean M, Garcia-Dorado, David, Engel, Felix B, Ferdinandy, Peter, Heusch, Gerd, Madonna, Rosalinda, Ovize, Michel, Ruiz-Meana, Marisol, Schulz, Rainer, Sluijter, Joost P G, Van Laake, Linda W, Yellon, Derek M, Hausenloy, Derek J

“…Ischaemic heart disease (IHD) remains the leading cause of death and disability worldwide. As a result, novel therapies are still needed to protect the heart…”
Get full text

The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria by Fouqué, A, Lepvrier, E, Debure, L, Gouriou, Y, Malleter, M, Delcroix, V, Ovize, M, Ducret, T, Li, C, Hammadi, M, Vacher, P, Legembre, P

“…Metalloprotease-processed CD95L (cl-CD95L) is a soluble cytokine that implements a PI3K/Ca(2+) signaling pathway in triple-negative breast cancer (TNBC) cells…”
Get full text

Clinical effects of cyclosporine in acute anterior myocardial infarction complicated by heart failure: A subgroup analysis of the CIRCUS Trial by Claeys, Marc J, Coussement, Patrick, Dubois, Philippe, Garcia-Dorado, D., Mewton, N., Amaz, C, Ovize, M.

Get full text

Mitochondrial permeability transition pore and postconditioning by GATEAU-ROESCH, Odile, ARGAUD, Laurent, OVIZE, Michel

“…Postconditioning has recently been described as a powerful cardioprotection that prevents lethal reperfusion injury. Growing evidence suggests that…”
Get full text

Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study by COUR, Martin, LOUFOUAT, Joseph, PAILLARD, Mélanie, AUGEUL, Lionel, GOUDABLE, Joëlle, OVIZE, Michel, ARGAUD, Laurent

“…Resuscitated cardiac arrest (CA), leading to harmful cardiovascular dysfunction and multiple organ failure, includes a whole-body hypoxia-reoxygenation…”
Get full text

PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning by BOPASSA, Jean-Chrisostome, FERRERA, René, GATEAU-ROESCH, Odile, COUTURE-LEPETIT, Elisabeth, OVIZE, Michel

“…We investigated whether phosphatidylinositol 3-kinase (PI3K) might regulate mitochondrial permeability transition pore (mPTP) opening in hearts reperfused with…”
Get full text

Assessment of left ventricular systolic function by deformation imaging derived from speckle tracking: a comparison between 2D and 3D echo modalities by Altman, Mikhail, Bergerot, Cyrille, Aussoleil, Alexandra, Davidsen, Einar S, Sibellas, Franck, Ovize, Michel, Bonnefoy-Cudraz, Eric, Thibault, Hélène, Derumeaux, Geneviève

“…Deformation imaging is undergoing continuous development with the emergence of new technologies allowing the evaluation of the different components of strain…”
Get full text

Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury by Argaud, Laurent, Gateau-Roesch, Odile, Muntean, Danina, Chalabreysse, Lara, Loufouat, Joseph, Robert, Dominique, Ovize, Michel

“…The aim of the present study was to determine whether specific inhibition of mitochondrial permeability transition (MPT) by NIM811 at the time of reperfusion…”
Get full text

No post-conditioning in the human heart with thrombolysis in myocardial infarction flow 2-3 on admission by Roubille, F, Mewton, N, Elbaz, M, Roth, O, Prunier, F, Cung, T T, Piot, C, Roncalli, J, Rioufol, G, Bonnefoy-Cudraz, E, Wiedemann, J Y, Furber, A, Jacquemin, L, Willoteaux, S, Abi-Khallil, W, Sanchez, I, Finet, G, Sibellas, F, Ranc, S, Boussaha, I, Croisille, P, Ovize, M

“…Proof-of-concept evidence suggests that mechanical ischaemic post-conditioning (PostC) reduces infarct size when applied immediately after culprit coronary…”
Get full text

One Hour Reperfusion is Enough to Assess Function and Infarct Size With TTC Staining in Langendorff Rat Model by Ferrera, R., Benhabbouche, S., Bopassa, J. C., Li, B., Ovize, M.

“…Background There is not general agreement concerning the optimal time of reperfusion necessary to assess myocardial function and necrosis on isolated perfused…”
Get full text

A fresh look at reperfusion injury by PIPER, H. M, GARCIA-DORADO, D, OVIZE, M

Get full text

Tissue kallikrein is required for the cardioprotective effect of Cyclosporin A in myocardial ischemia in the mouse by Youcef, G., Belaidi, E., Waeckel, L., Fazal, L., Clemessy, M., Vincent, M.P., Zadigue, G., Richer, C., Alhenc-Gelas, F., Ovize, M., Pizard, A.

“…Clinical and experimental studies suggest that pharmacological postconditioning with Cyclosporin A (CsA) reduces infarct size in cardiac ischemia and…”
Get full text

Low-pressure reperfusion alters mitochondrial permeability transition by Bopassa, J C, Michel, P, Gateau-Roesch, O, Ovize, M, Ferrera, R

“…We hypothesized that low-pressure reperfusion may limit myocardial necrosis and attenuate postischemic contractile dysfunction by inhibiting mitochondrial…”
Get more information

Effect and safety of morphine use in acute anterior ST-segment elevation myocardial infarction by Bonin, M., Mewton, N., Jossan, C., Ovize, M., Guérin, P.

Get full text