Search Results - "Overmeer, R M"

Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC by Overmeer, RM, Henken, FE, Snijders, PJF, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJM, Heideman, DAM, Wilting, SM, Murakami, Y, Ito, A, Meijer, CJLM, Steenbergen, RDM

“…We previously showed that silencing of TSLC1, recently renamed CADM1, is functionally involved in high-risk HPV-mediated cervical carcinogenesis. CADM1…”
Get full text

Sequential gene promoter methylation during HPV-induced cervical carcinogenesis by HENKEN, F. E, WILTING, S. M, OVERMEER, R. M, VAN RIETSCHOTEN, J. G. I, NYGREN, A. O. H, ERRAMI, A, SCHOUTEN, J. P, MEIJER, C. J. L. M, SNIJDERS, P. J. F, STEENBERGEN, R. D. M

“…We aimed to link DNA methylation events occurring in cervical carcinomas to distinct stages of HPV-induced transformation. Methylation specific-multiplex…”
Get full text

MAL promoter hypermethylation as a novel prognostic marker in gastric cancer by Buffart, T E, Overmeer, R M, Steenbergen, R D M, Tijssen, M, van Grieken, N C T, Snijders, P J F, Grabsch, H I, van de Velde, C J H, Carvalho, B, Meijer, G A

“…T-lymphocyte maturation associated protein, MAL, has been described as a tumour-suppressor gene with diagnostic value in colorectal and oesophageal cancers,…”
Get full text

In-training assessment: qualitative study of effects on supervision and feedback in an undergraduate clinical rotation by Daelmans, H E M, Overmeer, R M, van der Hem-Stokroos, H H, Scherpbier, A J J A, Stehouwer, C D A, van der Vleuten, C P M

“…Background  Supervision and feedback are essential factors that contribute to the learning environment in the context of workplace learning and their frequency…”
Get full text

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11 by Oosterhoff, D, Overmeer, R M, de Graaf, M, van der Meulen, I H, Giaccone, G, van Beusechem, V W, Haisma, H J, Pinedo, H M, Gerritsen, W R

“…CPT-11 (irinotecan or 7-ethyl-10[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin) is an anticancer agent in use for the treatment of colon cancer. In…”
Get full text

The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T‐DNA by van Attikum, Haico, Bundock, Paul, Overmeer, René M., Lee, Lan‐Ying, Gelvin, Stanton B., Hooykaas, Paul J. J.

“…The joining of breaks in the chromosomal DNA backbone by ligases in processes of replication, recombination and repair plays a crucial role in the maintenance…”
Get full text

Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells by CARETTE, Jan E, OVERMEER, Renée M, SCHAGEN, Frederik H. E, ALEMANY, Ramon, BARSKI, Oleg A, GERRITSEN, Winald R, VAN BEUSECHEM, Victor W

“…RNA interference (RNAi) is a posttranscriptional silencing mechanism triggered by double-stranded RNA that was recently shown to function in mammalian cells…”
Get full text

Association between dense CADM I promoter methylation and reduced protein expression in high-grade CIN and cervical SCC by OVERMEER, R. M, HENKEN, F. E, MEIJER, C. J. L. M, STEENBERGEN, R. D. M, SNIJDERS, P. J. F, CLAASSEN-KRAMER, D, BERKHOF, J, HELMERHORST, T. J. M, HEIDEMAN, D. A. M, WILTING, S. M, MURAKAMI, Y, ITO, A

Get full text

Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function by Wiegant, Wouter W, Overmeer, René M, Godthelp, Barbara C, van Buul, Paul P W, Zdzienicka, Małgorzata Z

“…The previously described Chinese hamster cell mutant V-C8 that is defective in Brca2 shows a very complex phenotype, including increased sensitivity towards a…”
Get more information

Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK sub(4) gene therapy by Heideman, DAM, Overmeer, R M, van Beusechem, VW, Lamers, W H, Hakvoort, TBM, Snijders, PJF, Craanen, ME, Offerhaus, GJA, Meijer, CJLM, Gerritsen, W R

“…NK sub(4) is an hepatocyte growth factor (HGF)-antagonist and a broad angiogenesis inhibitor. NK sub(4) gene therapy has confirmed antitumor efficacy on…”
Get full text

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT- II by OOSTERHOFF, D, OVERMEER, R. M, DE GRAAF, M, VAN DER MEULEN, I. H, GIACCONE, G, VAN BEUSECHEM, V. W, HAISMA, H. J, PINEDO, H. M, GERRITSEN, W. R

Get full text

Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK4 gene therapy by Heideman, Daniëlle A M, Overmeer, Renée M, van Beusechem, Victor W, Lamers, Wouter H, Hakvoort, Theodorus B M, Snijders, Peter J F, Craanen, Mikael E, Offerhaus, G Johan A, Meijer, Chris J L M, Gerritsen, Winald R

“…NK4 is an hepatocyte growth factor (HGF)-antagonist and a broad angiogenesis inhibitor. NK4 gene therapy has confirmed antitumor efficacy on cancers with…”
Get full text