Search Results - "Overman, C"
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Results on Low-Mass Weakly Interacting Massive Particles from an 11 kg d Target Exposure of DAMIC at SNOLAB
Published in Physical review letters (11-12-2020)“…We present constraints on the existence of weakly interacting massive particles (WIMPs) from an 11 kg d target exposure of the DAMIC experiment at the SNOLAB…”
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Coherent neutrino-nucleus scattering detection with a CsI[Na] scintillator at the SNS spallation source
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (11-02-2015)“…We study the possibility of using CsI[Na] scintillators as an advantageous target for the detection of coherent elastic neutrino-nucleus scattering (CENNS),…”
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Observation of coherent elastic neutrino-nucleus scattering
Published in Science (American Association for the Advancement of Science) (15-09-2017)“…The coherent elastic scattering of neutrinos off nuclei has eluded detection for four decades, even though its predicted cross section is by far the largest of…”
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Mechanical property anisotropy in ultra-thick copper electrodeposits
Published in Applied physics. A, Materials science & processing (01-09-2015)“…Electroplating was used as a purification method and produced thick (3.2–12.2 mm) copper deposits of ultra-high radiopurity. Due to the extreme thickness of…”
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Strength and strain hardening behavior of Cu-based bilayers and trilayers
Published in Scripta materialia (01-04-2011)“…Strain hardening in metallic multilayers is shown experimentally to be greater in trilayer films of Cu–Ni–Nb than bilayer films of Cu–Ni or Cu–Nb using both…”
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Quantifying Latent Impacts of an Introduced Piscivore: Pulsed Predatory Inertia of Lake Trout and Decline of Kokanee
Published in Transactions of the American Fisheries Society (1900) (01-01-2012)“…Introduced long-lived predators often cause significant impacts on their prey, but these impacts can be masked from detection due to high “predatory inertia”:…”
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Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori
Published in Current research in structural biology (01-01-2021)“…Helicobacter pylori (H. pylori) uses several outer membrane proteins for adhering to its host's gastric mucosa, an important step in establishing and…”
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Low-background gamma-ray spectrometry for the international monitoring system
Published in Applied radiation and isotopes (01-08-2017)“…PNNL has developed two low-background gamma-ray spectrometers in a new shallow underground laboratory, thereby significantly improving its ability to detect…”
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Optimization of simultaneous tritium–radiocarbon internal gas proportional counting
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (21-03-2016)“…Specific environmental applications can benefit from dual tritium and radiocarbon measurements in a single compound. Assuming typical environmental levels, it…”
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Development of a low-level (37)Ar calibration standard
Published in Applied radiation and isotopes (01-03-2016)“…Argon-37 is an environmental signature of an underground nuclear explosion. Producing and quantifying low-level (37)Ar standards is an important step in the…”
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Development of a low-level 39Ar calibration standard – Analysis by absolute gas counting measurements augmented with simulation
Published in Applied radiation and isotopes (01-08-2017)“…This paper describes the generation of 39Ar, via reactor irradiation of potassium carbonate, followed by quantitative analysis (length-compensated proportional…”
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Fatigue in patients with systemic lupus erythematosus: the role of dehydroepiandrosterone sulphate
Published in Lupus (01-12-2012)“…Fatigue is a major problem in systemic lupus erythematosus (SLE), but the physiological substrate of this fatigue is largely unclear. To examine if low levels…”
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The design, construction, and initial characterization of an ultra-low-background gas-proportional counting system
Published in Journal of radioanalytical and nuclear chemistry (01-05-2013)“…Over the past several years, the Pacific Northwest National Laboratory (PNNL) has developed an ultra-low-background proportional counter (ULBPC) technology…”
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The C-4 dark matter experiment
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-06-2013)“…We describe the experimental design of C-4, an expansion of the CoGeNT dark matter search to four identical detectors each approximately three times the mass…”
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A new shallow underground gas-proportional counting lab—First results and Ar-37 sensitivity
Published in Applied radiation and isotopes (01-11-2013)“…A new ultra-low-background proportional counter was recently developed with an internal volume of 100cm3 and has been characterized at pressures from 1–10atm…”
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Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles
Published in Bioscience reports (05-06-2013)“…The Eph (erythropoietin-producing hepatocellular carcinoma) B receptors are important in a variety of cellular processes through their roles in cell-to-cell…”
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A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding
Published in Biochemical journal (27-11-2020)“…The activation loop (A-loop) plays a key role in regulating the catalytic activity of protein kinases. Phosphorylation in this region enhances the phosphoryl…”
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Development of an absolute gas-counting capability for low to medium activities
Published in Applied radiation and isotopes (01-11-2013)“…Pacific Northwest National Laboratory (PNNL) is developing a capability to measure the absolute activity concentration of gaseous radionuclides using…”
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Controlling low-rate signal path microdischarge for an ultra-low-background proportional counter
Published in Journal of radioanalytical and nuclear chemistry (01-05-2013)“…Pacific Northwest National Laboratory (PNNL) has developed an ultra-low-background proportional counter (ULBPC) made of high purity copper. These detectors are…”
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Discovery of N‑(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)‑1H‑1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
Published in Journal of medicinal chemistry (11-10-2018)“…While the treatment of gastrointestinal stromal tumors (GISTs) has been revolutionized by the application of targeted tyrosine kinase inhibitors capable of…”
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