Search Results - "Ouyang, Yingshi"

Isolation of exosomes from whole blood by integrating acoustics and microfluidics by Wu, Mengxi, Ouyang, Yingshi, Wang, Zeyu, Zhang, Rui, Huang, Po-Hsun, Chen, Chuyi, Li, Hui, Li, Peng, Quinn, David, Dao, Ming, Suresh, Subra, Sadovsky, Yoel, Huang, Tony Jun

“…Exosomes are nanoscale extracellular vesicles that play an important role in many biological processes, including intercellular communications, antigen…”
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Unique microRNA Signals in Plasma Exosomes from Pregnancies Complicated by Preeclampsia by Li, Hui, Ouyang, Yingshi, Sadovsky, Elena, Parks, W. Tony, Chu, Tianjiao, Sadovsky, Yoel

“…Although preeclampsia is a common and serious complication of pregnancy, insight into its pathobiology and diagnosis is lacking. Circulating plasma exosomes,…”
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MicroRNAs in placental health and disease by Mouillet, Jean-François, PhD, Ouyang, Yingshi, PhD, Coyne, Carolyn B., PhD, Sadovsky, Yoel, MD

“…MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded by the genomes of most organisms. They regulate gene expression through…”
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Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection by Bayer, Avraham, Lennemann, Nicholas J., Ouyang, Yingshi, Bramley, John C., Morosky, Stefanie, Marques, Ernesto Torres De Azeved, Cherry, Sara, Sadovsky, Yoel, Coyne, Carolyn B.

“…During mammalian pregnancy, the placenta acts as a barrier between the maternal and fetal compartments. The recently observed association between Zika virus…”
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Human placental trophoblasts confer viral resistance to recipient cells by Delorme-Axford, Elizabeth, Donker, Rogier B., Mouillet, Jean-Francois, Chu, Tianjiao, Bayer, Avraham, Ouyang, Yingshi, Wang, Tianyi, Stolz, Donna B., Sarkar, Saumendra N., Morelli, Adrian E., Sadovsky, Yoel, Coyne, Carolyn B.

“…Placental trophoblasts form the interface between the fetal and maternal environments and serve to limit the maternal–fetal spread of viruses. Here we show…”
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Placental response to maternal SARS-CoV-2 infection by Mourad, Mirella, Jacob, Taylor, Sadovsky, Elena, Bejerano, Shai, Simone, Glicella Salazar-De, Bagalkot, Tarique Rajasaheb, Zucker, Jason, Yin, Michael T., Chang, Jennifer Y., Liu, Lihong, Debelenko, Larisa, Shawber, Carrie J., Firestein, Morgan, Ouyang, Yingshi, Gyamfi-Bannerman, Cynthia, Penn, Anna, Sorkin, Alexander, Wapner, Ronald, Sadovsky, Yoel

“…The coronavirus disease 2019 (COVID-19) pandemic affected people at all ages. Whereas pregnant women seemed to have a worse course of disease than age-matched…”
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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery by Yang, Yufeng, Ouyang, Yingshi, Yang, Lichuan, Beal, M. Flint, McQuibban, Angus, Vogel, Hannes, Lu, Bingwei

“…Mitochondria form dynamic tubular networks that undergo frequent morphological changes through fission and fusion, the imbalance of which can affect cell…”
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Acoustofluidic centrifuge for nanoparticle enrichment and separation by Gu, Yuyang, Chen, Chuyi, Mao, Zhangming, Bachman, Hunter, Becker, Ryan, Rufo, Joseph, Wang, Zeyu, Zhang, Peiran, Mai, John, Yang, Shujie, Zhang, Jinxin, Zhao, Shuaiguo, Ouyang, Yingshi, Wong, David T W, Sadovsky, Yoel, Huang, Tony Jun

“…Liquid droplets have been studied for decades and have recently experienced renewed attention as a simplified model for numerous fascinating physical phenomena…”
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Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin by Ouyang, Yingshi, Bagalkot, Tarique, Fitzgerald, Wendy, Sadovsky, Elena, Chu, Tianjiao, Martínez-Marchal, Ana, Brieño-Enríquez, Miguel, Su, Emily J, Margolis, Leonid, Sorkin, Alexander, Sadovsky, Yoel

“…The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a massive impact on human…”
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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin by Yang, Y, Gehrke, S, Imai, Y, Huang, Z, Ouyang, Y, Wang, J.W, Yang, L, Beal, M.F, Vogel, H, Lu, B

“…Mutations in Pink1, a gene encoding a Ser/Thr kinase with a mitochondrial-targeting signal, are associated with Parkinson's disease (PD), the most common…”
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Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling by Bayer, Avraham, Lennemann, Nicholas J., Ouyang, Yingshi, Sadovsky, Elena, Sheridan, Megan A., Roberts, R. Michael, Coyne, Carolyn B., Sadovsky, Yoel

“…Cultured primary human trophoblasts (PHT), derived from term placentas, are relatively resistant to infection by diverse viruses. The resistance can be…”
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Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon by Wang, Hongyan, Ouyang, Yingshi, Somers, W Gregory, Chia, William, Lu, Bingwei

“…Self-renewal and differentiation are cardinal features of stem cells. Asymmetric cell division provides one fundamental mechanism by which stem cell…”
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Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes by Barak, Oren, Lovelace, Tyler, Piekos, Samantha, Chu, Tianjiao, Cao, Zhishen, Sadovsky, Elena, Mouillet, Jean-Francois, Ouyang, Yingshi, Parks, W Tony, Hood, Leroy, Price, Nathan D, Benos, Panayiotis V, Sadovsky, Yoel

“…Placental dysfunction, a root cause of common syndromes affecting human pregnancy, such as preeclampsia (PE), fetal growth restriction (FGR), and spontaneous…”
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The role of trophoblastic microRNAs in placental viral infection by Mouillet, Jean-Francois, Ouyang, Yingshi, Bayer, Avraham, Coyne, Carolyn B, Sadovsky, Yoel

“…During the past decade, various types of small non-coding RNAs were found to be expressed in all kingdoms and phyla of life. Intense research efforts have…”
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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies by Li, Hui, Pinilla-Macua, Itziar, Ouyang, Yingshi, Sadovsky, Elena, Kajiwara, Kazuhiro, Sorkin, Alexander, Sadovsky, Yoel

“…Pregnancy is a unique situation, in which placenta-derived small extracellular vesicles (sEVs) may communicate with maternal and foetal tissues. While relevant…”
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High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT by Rufo, Joseph, Zhang, Peiran, Wang, Zeyu, Gu, Yuyang, Yang, Kaichun, Rich, Joseph, Chen, Chuyi, Zhong, Ruoyu, Jin, Ke, He, Ye, Xia, Jianping, Li, Ke, Wu, Jiarong, Ouyang, Yingshi, Sadovsky, Yoel, Lee, Luke P., Huang, Tony Jun

“…Extracellular vesicles (EVs) have been identified as promising biomarkers for the noninvasive diagnosis of various diseases. However, challenges in separating…”
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RNA Network Interactions During Differentiation of Human Trophoblasts by Chu, Tianjiao, Mouillet, Jean-Francois, Cao, Zhishen, Barak, Oren, Ouyang, Yingshi, Sadovsky, Yoel

“…In the human placenta, two trophoblast cell layers separate the maternal blood from the villous basement membrane and fetal capillary endothelial cells. The…”
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dp53 Restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and cyclin E by Ouyang, Yingshi, Song, Yan, Lu, Bingwei

“…Accumulating evidence suggests that tumor-initiating stem cells or cancer stem cells (CSCs) possibly originating from normal stem cells may be the root cause…”
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The lipase cofactor CGI58 controls placental lipolysis by Guerrero-Santoro, Jennifer, Morizane, Mayumi, Oh, Soo-Young, Mishima, Takuya, Goff, Julie P, Bildirici, Ibrahim, Sadovsky, Elena, Ouyang, Yingshi, Tyurin, Vladimir A, Tyurina, Yulia Y, Kagan, Valerian E, Sadovsky, Yoel

“…In eutherians, the placenta plays a critical role in the uptake, storage, and metabolism of lipids. These processes govern the availability of fatty acids to…”
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The impact of opioids on the transcriptional landscape of human villous trophoblasts by Sadovsky, Elena, Chu, Tianjiao, Barak, Oren, Sadovsky, Yoel, Ouyang, Yingshi

“…Opioid use disorder (OUD) is implicated in major obstetrical diseases such as fetal growth restriction. Whether or not opioids directly impact placental…”
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