Search Results - "Ouyang, Yeyun"

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    XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data by Berg, Jordan A, Belyeu, Jonathan R, Morgan, Jeffrey T, Ouyang, Yeyun, Bott, Alex J, Quinlan, Aaron R, Gertz, Jason, Rutter, Jared

    Published in PLoS computational biology (01-01-2020)
    “…Ribosome profiling, an application of nucleic acid sequencing for monitoring ribosome activity, has revolutionized our understanding of protein translation…”
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    Journal Article
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    Maestro of the SereNADe: SLC25A51 Orchestrates Mitochondrial NAD by Ouyang, Yeyun, Bott, Alex J., Rutter, Jared

    “…Recently, three groups, Girardi et al., Kory et al., and Luongo et al., independently identified solute carrier (SLC) 25A51 as the long-sought, major…”
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    Journal Article
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    Investigating the Regulation of Mitochondrial Membrane Potential by Ouyang, Yeyun

    Published 01-01-2023
    “…Mitochondrial membrane potential plays an important role in regulating many essential cellular processes inside and outside mitochondria. Other than its most…”
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    Dissertation
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    ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly by Van Vranken, Jonathan G., Nowinski, Sara M., Clowers, Katie J., Jeong, Mi-Young, Ouyang, Yeyun, Berg, Jordan A., Gygi, Jeremy P., Gygi, Steven P., Winge, Dennis R., Rutter, Jared

    Published in Molecular cell (16-08-2018)
    “…The electron transport chain (ETC) is an important participant in cellular energy conversion, but its biogenesis presents the cell with numerous challenges. To…”
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    Journal Article
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    Metaboverse enables automated discovery and visualization of diverse metabolic regulatory patterns by Berg, Jordan A., Zhou, Youjia, Ouyang, Yeyun, Cluntun, Ahmad A., Waller, T. Cameron, Conway, Megan E., Nowinski, Sara M., Van Ry, Tyler, George, Ian, Cox, James E., Wang, Bei, Rutter, Jared

    Published in Nature cell biology (01-04-2023)
    “…Metabolism is intertwined with various cellular processes, including controlling cell fate, influencing tumorigenesis, participating in stress responses and…”
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    Journal Article
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    Exploring the functional role of an ancient mitochondrial fatty acid synthesis pathway by Dove, Katja K, Kadirova, Malika F, Nowinski, Sara M, Ouyang, Yeyun, Van Vranken, Jon G, Rutter, Jared

    Published in The FASEB journal (01-04-2019)
    “…Fatty acid synthesis plays a crucial role in the cellular energetic landscape. Cytoplasmic Fatty Acid Synthesis (FAS) generates fatty acid intermediates that…”
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    Journal Article
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    Callyspongiolide Is a Potent Inhibitor of the Vacuolar ATPase by Fogarty, Sarah, Ouyang, Yeyun, Li, Liubo, Chen, Yu-chan, Rane, Hallie, Manoni, Francesco, Parra, Karlett J, Rutter, Jared, Harran, Patrick G

    “…Callyspongiolide is a marine-derived macrolide that kills cells in a caspase-independent manner. NCI COMPARE analysis of human tumor cell line toxicity data…”
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    Journal Article
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    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway by Wei, Peng, Bott, Alex J, Cluntun, Ahmad A, Morgan, Jeffrey T, Cunningham, Corey N, Schell, John C, Ouyang, Yeyun, Ficarro, Scott B, Marto, Jarrod A, Danial, Nika N, DeBerardinis, Ralph J, Rutter, Jared

    Published in Science advances (30-09-2022)
    “…The fate of pyruvate is a defining feature in many cell types. One major fate is mitochondrial entry via the mitochondrial pyruvate carrier (MPC). We found…”
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    Journal Article