Search Results - "Ouwendijk, Werner J. D."

Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients by van Nierop, Gijsbert P., van Luijn, Marvin M., Michels, Samira S., Melief, Marie-Jose, Janssen, Malou, Langerak, Anton W., Ouwendijk, Werner J. D., Hintzen, Rogier Q., Verjans, Georges M. G. M.

“…T cells are considered pivotal in the pathology of multiple sclerosis (MS), but their function and antigen specificity are unknown. To unravel the role of T…”
Get full text

A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61 by Depledge, Daniel P., Ouwendijk, Werner J. D., Sadaoka, Tomohiko, Braspenning, Shirley E., Mori, Yasuko, Cohrs, Randall J., Verjans, Georges M. G. M., Breuer, Judith

“…Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent infection in the neurons of >90% humans worldwide, reactivating in one-third to…”
Get full text

The architecture of the simian varicella virus transcriptome by Braspenning, Shirley E, Verjans, Georges M G M, Mehraban, Tamana, Messaoudi, Ilhem, Depledge, Daniel P, Ouwendijk, Werner J D

“…Primary infection with varicella-zoster virus (VZV) causes varicella and the establishment of lifelong latency in sensory ganglion neurons. In one-third of…”
Get full text

Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency by Ouwendijk, Werner J. D., Depledge, Daniel P., Rajbhandari, Labchan, Lenac Rovis, Tihana, Jonjic, Stipan, Breuer, Judith, Venkatesan, Arun, Verjans, Georges M. G. M., Sadaoka, Tomohiko

“…Varicella-zoster virus (VZV) establishes lifelong neuronal latency in most humans world-wide, reactivating in one-third to cause herpes zoster and occasionally…”
Get full text

Molecular Aspects of Varicella-Zoster Virus Latency by Depledge, Daniel P, Sadaoka, Tomohiko, Ouwendijk, Werner J D

“…Primary varicella-zoster virus (VZV) infection causes varicella (chickenpox) and the establishment of a lifelong latent infection in ganglionic neurons. VZV…”
Get full text

Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures by Rashidi, Ahmad S, Tran, Diana N, Peelen, Caithlin R, van Gent, Michiel, Ouwendijk, Werner J D, Verjans, Georges M G M

“…Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in…”
Get full text

T-cells in human trigeminal ganglia express canonical tissue-resident memory T-cell markers by Unger, Peter-Paul A, Oja, Anna E, Khemai-Mehraban, Tamana, Ouwendijk, Werner J D, Hombrink, Pleun, Verjans, Georges M G M

“…Trigeminal ganglia (TG) neurons are the main site of lifelong latent herpes simplex virus type 1 (HSV-1) infection. T-cells in ganglia contribute to long-term…”
Get full text

Selective retention of virus-specific tissue-resident T cells in healed skin after recovery from herpes zoster by Laing, Kerry J., Ouwendijk, Werner J. D., Campbell, Victoria L., McClurkan, Christopher L., Mortazavi, Shahin, Elder Waters, Michael, Krist, Maxwell P., Tu, Richard, Nguyen, Nhi, Basu, Krithi, Miao, Congrong, Schmid, D. Scott, Johnston, Christine, Verjans, Georges M. G. M., Koelle, David M.

“…Herpes zoster is a localized skin infection caused by reactivation of latent varicella-zoster virus. Tissue-resident T cells likely control skin infections…”
Get full text

Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia by van Gent, Michiel, Ouwendijk, Werner J D, Campbell, Victoria L, Laing, Kerry J, Verjans, Georges M G M, Koelle, David M

“…Trigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific T-cells are considered…”
Get full text

Adenosine Deaminase Acts as a Natural Antagonist for Dipeptidyl Peptidase 4-Mediated Entry of the Middle East Respiratory Syndrome Coronavirus by Raj, V Stalin, Smits, Saskia L, Provacia, Lisette B, van den Brand, Judith M A, Wiersma, Lidewij, Ouwendijk, Werner J D, Bestebroer, Theo M, Spronken, Monique I, van Amerongen, Geert, Rottier, Peter J M, Fouchier, Ron A M, Bosch, Berend Jan, Osterhaus, Albert D M E, Haagmans, Bart L

“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Prevalence of Intrathecal Acyclovir Resistant Virus in Herpes Simplex Encephalitis Patients by Mitterreiter, Johanna G, Titulaer, Maarten J, van Nierop, Gijsbert P, van Kampen, Jeroen J A, Aron, Georgina I, Osterhaus, Albert D M E, Verjans, Georges M G M, Ouwendijk, Werner J D

“…Herpes simplex encephalitis (HSE) is a life-threatening complication of herpes simplex virus (HSV) infection. Acyclovir (ACV) is the antiviral treatment of…”
Get full text

Restricted Varicella-Zoster Virus Transcription in Human Trigeminal Ganglia Obtained Soon after Death by OUWENDIJK, Werner J. D, CHOE, Alexander, NAGEL, Maria A, GILDEN, Don, OSTERHAUS, Albert D. M. E, COHRS, Randall J, VERJANS, Georges M. G. M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration by González-Motos, Víctor, Jürgens, Carina, Ritter, Birgit, Kropp, Kai A, Durán, Verónica, Larsen, Olav, Binz, Anne, Ouwendijk, Werner J D, Lenac Rovis, Tihana, Jonjic, Stipan, Verjans, Georges M G M, Sodeik, Beate, Krey, Thomas, Bauerfeind, Rudolf, Schulz, Thomas F, Kaufer, Benedikt B, Kalinke, Ulrich, Proudfoot, Amanda E I, Rosenkilde, Mette M, Viejo-Borbolla, Abel

“…Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection…”
Get full text

Immunobiology of Varicella-Zoster Virus Infection by Laing, Kerry J, Ouwendijk, Werner J D, Koelle, David M, Verjans, Georges M G M

“…Varicella-zoster virus (VZV) causes clinically significant illness during acute and recurrent infection accompanied by robust innate and acquired immune…”
Get full text

T-Cell Infiltration Correlates with CXCL10 Expression in Ganglia of Cynomolgus Macaques with Reactivated Simian Varicella Virus by Ouwendijk, Werner J D, Abendroth, Allison, Traina-Dorge, Vicki, Getu, Sarah, Steain, Megan, Wellish, Mary, Andeweg, Arno C, Osterhaus, Albert D M E, Gilden, Don, Verjans, Georges M G M, Mahalingam, Ravi

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Comprehensive Analysis of Varicella-Zoster Virus Proteins Using a New Monoclonal Antibody Collection by Lenac Roviš, Tihana, Bailer, Susanne M, Pothineni, Venkata R, Ouwendijk, Werner J D, Šimić, Hrvoje, Babić, Marina, Miklić, Karmela, Malić, Suzana, Verweij, Marieke C, Baiker, Armin, Gonzalez, Orland, von Brunn, Albrecht, Zimmer, Ralf, Früh, Klaus, Verjans, Georges M G M, Jonjić, Stipan, Haas, Jürgen

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Characterization of the immune response in ganglia after primary simian varicella virus infection by Ouwendijk, Werner J. D., Getu, Sarah, Mahalingam, Ravi, Gilden, Don, Osterhaus, Albert D. M. E., Verjans, Georges M. G. M.

“…Primary simian varicella virus (SVV) infection in non-human primates causes varicella, after which the virus becomes latent in ganglionic neurons and…”
Get full text

Longitudinal study on oral shedding of herpes simplex virus 1 and varicella-zoster virus in individuals infected with HIV by van Velzen, Monique, Ouwendijk, Werner J.D., Selke, Stacy, Pas, Suzan D., van Loenen, Freek B., Osterhaus, Albert D.M.E., Wald, Anna, Verjans, Georges M.G.M.

“…Primary herpes simplex virus 1 (HSV‐1) and varicella‐zoster virus (VZV) infection leads to a life‐long latent infection of ganglia innervating the oral mucosa…”
Get full text

No evidence of aberrant amyloid β and phosphorylated tau expression in herpes simplex virus‐infected neurons of the trigeminal ganglia and brain by Tran, Diana N., Bakx, Amy T. C. M., Dis, Vera, Aronica, Eleonora, Verdijk, Robert M., Ouwendijk, Werner J. D.

“…Increasing evidence supports the role of neurotropic herpes simplex virus 1 (HSV‐1) in the pathogenesis of Alzheimer's disease (AD). However, it is unclear…”
Get full text

Decoding the Architecture of the Varicella-Zoster Virus Transcriptome by Braspenning, Shirley E, Sadaoka, Tomohiko, Breuer, Judith, Verjans, Georges M G M, Ouwendijk, Werner J D, Depledge, Daniel P

“…Varicella-zoster virus (VZV), a double-stranded DNA virus, causes varicella, establishes lifelong latency in ganglionic neurons, and reactivates later in life…”
Get full text