Search Results - "Ouvrier, Blake"
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Senescence and SASP Are Potential Therapeutic Targets for Ischemic Stroke
Published in Pharmaceuticals (Basel, Switzerland) (28-02-2024)“…Aging is a known co-morbidity of ischemic stroke with its risk and severity increasing every year past 55+. While many of the current stroke therapies have…”
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The Potential Role of Integrin Signaling in Memory and Cognitive Impairment
Published in Biomolecules (Basel, Switzerland) (05-01-2023)“…Dementia currently has no cure and, due to the increased prevalence and associated economic and personal burden of this condition, current research efforts for…”
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LG3 improves the cognitive decline associated with cerebral amyloid angiopathy in APPSwDI mice
Published in Cerebral circulation - cognition and behavior (2024)“…A common condition experienced by individuals with dementia is cerebral amyloid angiopathy (CAA), characterized by the accumulation of amyloid beta (Aβ) in…”
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SARS-CoV-2-induced brain endothelial barrier disruption and neuroinflammation are ameliorated by α5 integrin inhibitor ATN 161
Published in Cerebral circulation - cognition and behavior (2024)“…The novel coronavirus SARS-CoV-2 infection can cause numerous symptoms, especially in patients with comorbidities such as chronic lung or cerebrovascular…”
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Abstract TP314: The α5 Integrin Inhibitor ATN161 Mitigates SARS-CoV-2- Induced Brain Endothelial Barrier Disruption and Neuroinflammation α5 Integrin Inhibitor ATN 161
Published in Stroke (1970) (01-02-2024)“…Abstract only Introduction: Although SARS-CoV-2 infection can cause a wide range of mild to severe symptoms, the pathophysiology of acute and long-term…”
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Abstract TP14: Translational Modeling Of Morphological And Physiological Features Of Vascular Dementia: A Review
Published in Stroke (1970) (01-02-2022)“…Vascular dementia (VaD) is the second-most common form of dementia, accounting for 20% of all dementia cases. Although the pathobiology of VaD is poorly…”
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Abstract TMP19: Atn-161 Prevents α5 Integrin-mediated Tight Junction Disruption Caused By Sars-cov-2 And Its Delta Variant In Brain Endothelial Cells
Published in Stroke (1970) (01-02-2022)“…Patients with significant cerebrovascular comorbidities (e.g. brain ischemia, vascular dementia) are more affected and are more likely to have worsened…”
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Abstract TP21: The Role Of Interleukin-1α Cytokine In Poststroke Inflammation
Published in Stroke (1970) (01-02-2022)“…Stroke remains the second leading cause of death globally, with a total of 5.5 million deaths in 2016 and an estimated global lifetime risk of stroke for those…”
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Effect of Diet on Cognitive Function and Gut Microbiota in Aged Rats
Published in Alzheimer's & dementia (01-12-2023)“…Background Many patients with mild cognitive impairment and Alzheimer’s disease have alterations in the gut microbiota. Dietary consumption directly modulates…”
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Effect of diet on cognitive function and gut microbiota
Published in Alzheimer's & dementia (01-12-2022)“…Background Alterations in the gut microbiota have been observed in patients with mild cognitive impairment and Alzheimer’s disease. Dietary consumption…”
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A Mediterranean Diet Enhances Cognitive Function and Modulates the Gut Microbiota
Published in Current developments in nutrition (01-06-2022)“…The gut-microbiome-brain axis is an underexplored mechanism that may mitigate the development of mild cognitive impairment. The objective of this study was to…”
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