Search Results - "Ouvrier, Blake"

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  1. 1

    Senescence and SASP Are Potential Therapeutic Targets for Ischemic Stroke by Ouvrier, Blake, Ismael, Saifudeen, Bix, Gregory Jaye

    Published in Pharmaceuticals (Basel, Switzerland) (28-02-2024)
    “…Aging is a known co-morbidity of ischemic stroke with its risk and severity increasing every year past 55+. While many of the current stroke therapies have…”
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    Journal Article
  2. 2

    The Potential Role of Integrin Signaling in Memory and Cognitive Impairment by Biose, Ifechukwude Joachim, Ismael, Saifudeen, Ouvrier, Blake, White, Amanda Louise, Bix, Gregory Jaye

    Published in Biomolecules (Basel, Switzerland) (05-01-2023)
    “…Dementia currently has no cure and, due to the increased prevalence and associated economic and personal burden of this condition, current research efforts for…”
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  3. 3

    LG3 improves the cognitive decline associated with cerebral amyloid angiopathy in APPSwDI mice by Cioma, Jozef, Biose, Ifechukwude, Ismael, Saifudeen, Wang, Habby, Ouvrier, Blake, Kelly, Louise, Carare, Roxana, Bix, Gregory

    “…A common condition experienced by individuals with dementia is cerebral amyloid angiopathy (CAA), characterized by the accumulation of amyloid beta (Aβ) in…”
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  4. 4

    SARS-CoV-2-induced brain endothelial barrier disruption and neuroinflammation are ameliorated by α5 integrin inhibitor ATN 161 by Amruta, Narayanappa, Gressett, Timothy E, Volic, Milla, Ouvrier, Blake, Ismael, Saifudeen, Talkington, Grant, Bix, Gregory

    “…The novel coronavirus SARS-CoV-2 infection can cause numerous symptoms, especially in patients with comorbidities such as chronic lung or cerebrovascular…”
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  5. 5

    Abstract TP314: The α5 Integrin Inhibitor ATN161 Mitigates SARS-CoV-2- Induced Brain Endothelial Barrier Disruption and Neuroinflammation α5 Integrin Inhibitor ATN 161 by Umar, Meenakshi, Amruta, Narayanappa, Gressett, Timothy E, Volic, Milla, Ouvrier, Blake, Ismael, Saifudeen, Talkington, Grant, Bix, Gregory J

    Published in Stroke (1970) (01-02-2024)
    “…Abstract only Introduction: Although SARS-CoV-2 infection can cause a wide range of mild to severe symptoms, the pathophysiology of acute and long-term…”
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  6. 6

    Abstract TP14: Translational Modeling Of Morphological And Physiological Features Of Vascular Dementia: A Review by Biose, Ifechukwude J, Bhatnagar, Somya, Gressett, Timothy, Ouvrier, Blake, Solch, Rebecca, Narayanappa, Amruta, Bix, Gregory J

    Published in Stroke (1970) (01-02-2022)
    “…Vascular dementia (VaD) is the second-most common form of dementia, accounting for 20% of all dementia cases. Although the pathobiology of VaD is poorly…”
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  7. 7

    Abstract TMP19: Atn-161 Prevents α5 Integrin-mediated Tight Junction Disruption Caused By Sars-cov-2 And Its Delta Variant In Brain Endothelial Cells by Narayanappa, Amruta, Eskew, William, Ouvrier, Blake, Biose, Ifechukwude J, Hefter, Sophie, Gressett, Timothy E, Khan, Pervez, Bix, Gregory J

    Published in Stroke (1970) (01-02-2022)
    “…Patients with significant cerebrovascular comorbidities (e.g. brain ischemia, vascular dementia) are more affected and are more likely to have worsened…”
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  8. 8

    Abstract TP21: The Role Of Interleukin-1α Cytokine In Poststroke Inflammation by Lemarchand, Eloise, Ouvrier, Blake, Rahman, Abir A, Wong, Raymond, Narayanappa, Amruta, Gressett, Timothy, Pinteaux, Emmanuel, Bix, Gregory J

    Published in Stroke (1970) (01-02-2022)
    “…Stroke remains the second leading cause of death globally, with a total of 5.5 million deaths in 2016 and an estimated global lifetime risk of stroke for those…”
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  9. 9

    Effect of Diet on Cognitive Function and Gut Microbiota in Aged Rats by Solch‐Ottaiano, Rebecca J, Harper, Colin, Engler‐Chiurazzi, Elizabeth, Wang, Hanyun, Ouvrier, Blake, McDonald, Katherine, Bix, Gregory J, Biose, Ifechukwude Joachim, Maraganore, Demetrius M

    Published in Alzheimer's & dementia (01-12-2023)
    “…Background Many patients with mild cognitive impairment and Alzheimer’s disease have alterations in the gut microbiota. Dietary consumption directly modulates…”
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  10. 10

    Effect of diet on cognitive function and gut microbiota by Solch, Rebecca J, Engler‐Chiurazzi, Elizabeth, Harper, Colin, Wasson, Savannah, Ogbonna, Sharon, Ouvrier, Blake, McDonald, Katherine, Wang, Hanyun, Biose, Ifechukwude Joachim, Bix, Gregory J, Maraganore, Demetrius M

    Published in Alzheimer's & dementia (01-12-2022)
    “…Background Alterations in the gut microbiota have been observed in patients with mild cognitive impairment and Alzheimer’s disease. Dietary consumption…”
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    Journal Article
  11. 11

    A Mediterranean Diet Enhances Cognitive Function and Modulates the Gut Microbiota by Solch, Rebecca, Engler-Chiurazzi, Elizabeth, Harper, Colin, Wasson, Savannah, Ogbonna, Sharon, Ouvrier, Blake, Wang, Hanyun, McDonald, Katherine, Biose, Ifechukwude, Gregory, Bix, Maraganore, Demetrius

    Published in Current developments in nutrition (01-06-2022)
    “…The gut-microbiome-brain axis is an underexplored mechanism that may mitigate the development of mild cognitive impairment. The objective of this study was to…”
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    Journal Article