Search Results - "Outhred, Tim"
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Therapeutic Mechanisms of Lithium in Bipolar Disorder: Recent Advances and Current Understanding
Published in CNS drugs (01-10-2016)“…Lithium is the most effective and well established treatment for bipolar disorder, and it has a broad array of effects within cellular pathways. However, the…”
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Modeling suicide in bipolar disorders
Published in Bipolar disorders (01-06-2018)“…Introduction Suicide is a multicausal human behavior, with devastating and immensely distressing consequences. Its prevalence is estimated to be 20–30 times…”
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Interactions of OXTR rs53576 and emotional trauma on hippocampal volumes and perceived social support in adolescent girls
Published in Psychoneuroendocrinology (01-05-2020)“…•In everyday life, social behaviour both influences, and is itself influenced by biology.•The OXTR rs53576 is important for social behaviour and is expressed…”
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The effects of childhood trauma on adolescent hippocampal subfields
Published in Australian and New Zealand journal of psychiatry (01-05-2019)“…Objective: Mood disorders are more common among girls and typically emerge during adolescence. The precise reasons for this are unknown, but among the many…”
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Matter over mind: a randomised-controlled trial of single-session biofeedback training on performance anxiety and heart rate variability in musicians
Published in PloS one (04-10-2012)“…Musical performance is a skilled activity performed under intense pressure, thus is often a profound source of anxiety. In other contexts, anxiety and its…”
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Acute neural effects of selective serotonin reuptake inhibitors versus noradrenaline reuptake inhibitors on emotion processing: Implications for differential treatment efficacy
Published in Neuroscience and biobehavioral reviews (01-09-2013)“…Clinical research has demonstrated differential efficacy of selective serotonin reuptake inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs),…”
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The Lithium Battery: assessing the neurocognitive profile of lithium in bipolar disorder
Published in Bipolar disorders (01-03-2016)“…Objective The aim of the present study was to characterize the neurocognitive effects of lithium in bipolar disorder to inform clinical and research approaches…”
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Cognitive side-effects of electroconvulsive therapy: what are they, how to monitor them and what to tell patients
Published in BJPsych open (01-05-2020)“…Electroconvulsive therapy (ECT) is recommended in treatment guidelines as an efficacious therapy for treatment-resistant depression. However, it has been…”
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Torture exposure and the functional brain: investigating disruptions to intrinsic network connectivity using resting state fMRI
Published in Translational psychiatry (26-01-2022)“…Torture has profound psychological and physiological consequences for survivors. While some brain structures and functions appear altered in torture survivors,…”
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Correction: Torture exposure and the functional brain: investigating disruptions to intrinsic network connectivity using resting state fMRI
Published in Translational psychiatry (21-02-2022)Get full text
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Impact of acute administration of escitalopram on the processing of emotional and neutral images: a randomized crossover fMRI study of healthy women
Published in Journal of psychiatry & neuroscience (01-07-2014)“…Background Acute neural effects of antidepressant medication on emotion processing biases may provide the foundation on which clinical outcomes are based…”
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Refugee visa insecurity disrupts the brain's default mode network
Published in European journal of psychotraumatology (2023)“…Refugee visa insecurity disrupts default mode network (DMN) connectivity - a core network that supports the internal construction of the self. Refugees living…”
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Pregnant mothers with resolved anxiety disorders and their offspring have reduced heart rate variability: implications for the health of children
Published in PloS one (10-12-2013)“…Active anxiety disorders have lasting detrimental effects on pregnant mothers and their offspring but it is unknown if historical, non-active, maternal anxiety…”
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The contribution of BDNF and 5-HTT polymorphisms and early life stress to the heterogeneity of major depressive disorder: A preliminary study
Published in Australian and New Zealand journal of psychiatry (01-01-2012)“…Objective: Two reported genetic polymorphisms related to the production of brain-derived neurotrophic factor (BNDF) and reuptake by the serotonin transporter…”
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Defining a mood stabiliser: novel framework for research and clinical practice
Published in BJPsych open (01-07-2018)“…The term ‘mood stabiliser’ is ill-defined and lacks clinical utility. We propose a framework to evaluate medications and effectively communicate their mood…”
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The Use of Lithium for the Treatment of Bipolar Disorder: Recommendations from Clinical Practice Guidelines
Published in Journal of affective disorders (01-08-2017)“…Abstract Background Lithium is an effective mood stabilizer that is used principally for the management of bipolar disorder (BD). Its administration is complex…”
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Lithiumeter: Version 2.0
Published in Bipolar disorders (01-12-2016)“…Background The Lithiumeter was developed as a visual and practical guide for determining lithium levels in the management of bipolar disorder (BD). It appears…”
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Bipolar II Disorder Is a Myth
Published in Canadian journal of psychiatry (01-08-2019)Get full text
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Default mode dysfunction underpins suicidal activity in mood disorders
Published in Psychological medicine (01-05-2020)“…Suicide is a serious and not uncommon consequence of mood disorders that occurs primarily when individuals are depressed. Understanding the neurobiology of…”
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Resting-state neural network disturbances that underpin the emergence of emotional symptoms in adolescent girls: resting-state fMRI study
Published in British journal of psychiatry (01-09-2019)“…Subsyndromal emotional symptoms in adolescence may represent precursors for full-blown emotional disorders in early adulthood. Understanding the…”
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