Search Results - "Oury, T D"

RAGE‐dependent VCAM‐1 expression in the lung endothelium mediates IL‐33‐induced allergic airway inflammation by Perkins, T. N., Oczypok, E. A., Milutinovic, P. S., Dutz, R. E., Oury, T. D.

“…Background The receptor for advanced glycation endproducts (RAGE) has been implicated as a critical molecule in the pathogenesis of experimental…”
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Extracellular superoxide dismutase has a highly specific localization in idiopathic pulmonary fibrosis/usual interstitial pneumonia by Kinnula, V L, Hodgson, U A, Lakari, E K, Tan, R J, Sormunen, R T, Soini, Y M, Kakko, S J, Laitinen, T H, Oury, T D, Pääkkö, P K

“…Aims : Recent studies suggest the importance of oxidant stress in the progression of pulmonary fibrosis. The aim of this study was to investigate extracellular…”
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Impairment of Long-term Potentiation and Associative Memory in Mice That Overexpress Extracellular Superoxide Dismutase by Thiels, Edda, Urban, Nathan N, Gonzalez-Burgos, Guillermo R, Kanterewicz, Beatriz I, Barrionuevo, German, Chu, Charleen T, Oury, Tim D, Klann, Eric

“…Reactive oxygen species, including superoxide, generally are considered neurotoxic molecules whose effects can be alleviated by antioxidants. Different from…”
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Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia by Sheng, H, Bart, R.D, Oury, T.D, Pearlstein, R.D, Crapo, J.D, Warner, D.S

“…Transgenic mice, which had been transfected with the human extracellular superoxide dismutase gene, causing an approximate five-fold increase in brain…”
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Extracellular superoxide dismutase: a regulator of nitric oxide bioavailability by Oury, T D, Day, B J, Crapo, J D

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Attenuation of Bleomycin-Induced Pulmonary Fibrosis by a Catalytic Antioxidant Metalloporphyrin by Oury, Tim D, Thakker, Kailas, Menache, Margaret, Chang, Ling-Yi, Crapo, James D, Day, Brian J

“…Oxidative stress plays an important role in the development of fibrotic responses in the lung. However, it is not clear whether inhibiting oxidative stress…”
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Immunocytochemical localization of extracellular superoxide dismutase in human lung by Oury, T D, Chang, L Y, Marklund, S L, Day, B J, Crapo, J D

“…Extracellular superoxide dismutase (EC-SOD) is a principal enzymatic scavenger of the superoxide anion in extracellular spaces. It is thought to be important…”
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Manganese superoxide dismutase is increased in the airways of smokers' lungs by Harju, T, Kaarteenaho-Wiik, R, Sirvio, R, Paakko, P, Crapo, J.D, Oury, T.D, Soini, Y, Kinnula, V.L

“…Oxidant stress is a key mechanism for smoking-induced chronic obstructive pulmonary disease (COPD). Smoking has been shown to upregulate several antioxidant…”
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Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide by OURY, T. D, PIANTADOSI, C. A, CRAPO, J. D

“…The role of extracellular superoxide in the pathogenesis of vasogenic edema was studied using transgenic mice expressing a 5-fold increase in extracellular…”
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Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity by Oury, T D, Ho, Y S, Piantadosi, C A, Crapo, J D

“…Although reactive O2 species appear to participate in central nervous system (CNS) O2 toxicity, the exact roles of different reactive O2 species are…”
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Localization of extracellular superoxide dismutase in adult mouse brain by Oury, Tim D., Card, J.Patrick, Klann, Eric

“…Extracellular superoxide dismutase (EC-SOD) is one of three mammalian SOD isozymes. Although there is knowledge of the functional role of EC-SOD in arteries,…”
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Extracellular superoxide dismutase localization and activity within the human placenta by Boggessa, K.A., Oury, T.D., Kay, H.H., Crapo, J.D.

“…Maintenance of low vascular tone within the placenta is mediated by nitric oxide (NO). The half-life of NO is very short, as superoxide anion (O 2 tt̄) rapidly…”
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Middle ear carcinoid: An indolent tumor with metastatic potential by Mooney, Eoghan E., Dodd, Leslie G., Oury, Tim D., Burchette, James L., Layfield, Lester J., Scher, Richard L., Cohen, James I.

“…Background Neuroendocrine tumors of the head and neck region may present problems in diagnosis. Middle ear carcinoid is a rare, recently recognized tumor,…”
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Ultrastructural features of diffuse malignant mesotheliomas by Oury, Tim D, Hammar, Samuel P, Roggli, Victor L

“…The distinction of malignant mesothelioma from tumors metastatic to the serosal membranes can often be made based on the results of histochemical or…”
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Differential localization of placental extracellular superoxide dismutase as pregnancy progresses by Boggess, Kim A., Kay, Helen H., Crapo, James D., Moore, William F., Suliman, Hagir B., Oury, Tim D.

“…Objective: The aim of this study was to determine placental localization and activity of extracellular superoxide dismutase, a nitric oxide modulator, during…”
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Cerebral amino acid, norepinephrine and nitric oxide metabolism in CNS oxygen toxicity by Zhang, J, Su, Y, Oury, T D, Piantadosi, C A

“…CNS oxygen (O2) toxicity is complex, and the etiology of its most severe manifestation, O2 convulsions, is yet to be determined. A role for depletion of the…”
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Lymphoma of the pituitary gland: an unusual presentation of central nervous system lymphoma in AIDS by Gottfredsson, M, Oury, T D, Bernstein, C, Carpenter, C, Bartlett, J A

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Extracellular superoxide dismutase in vessels and airways of humans and baboons by Oury, Tim D., Day, Brian J., Crapo, James D.

“…Extracellular superoxide dismutase (EC SOD) is generally the least abundant SOD isozyme in tissues, while the intracellular Cu,Zn SOD is usually the most…”
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Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment by Fattman, C L, Chu, C T, Kulich, S M, Enghild, J J, Oury, T D

“…The antioxidant enzyme extracellular superoxide dismutase (EC-SOD) is highly expressed in the extracellular matrix of lung tissue and is believed to protect…”
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The Intracellular Proteolytic Processing of Extracellular Superoxide Dismutase (EC-SOD) is a Two-step Event by Olsen, Dorte Aa, Petersen, Steen V., Oury, Tim D., Valnickova, Zuzana, Thøgersen, Ida B., Kristensen, Torsten, Bowler, Russel P., Crapo, James D., Enghild, Jan J.

“…Extracellular superoxide dismutase (EC-SOD) is a tetramer composed of either intact (Trp 1 –Ala 222 ) or proteolytically cleaved (Trp 1 –Glu 209 )…”
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