Search Results - "Oury, C."

Platelets contribute to the initiation of colitis‐associated cancer by promoting immunosuppression by Servais, L., Wéra, O., Dibato Epoh, J., Delierneux, C., Bouznad, N., Rahmouni, S., Mazzucchelli, G., Baiwir, D., Delvenne, P., Lancellotti, P., Oury, C.

“…Essentials Inflammation plays a key role in the development of colorectal cancer. Understanding mechanisms of cancer initiation might reveal new anticancer…”
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Targeting of C‐type lectin‐like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides: reply by Delierneux, C., Donis, N., Servais, L., Wéra, O., Lancellotti, P., Oury, C.

“…We provide here a new set of data supporting the involvement of multiple platelet receptors in CpG ODN platelet activating effects. We observed some…”
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The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets by Onselaer, M-B, Oury, C, Hunter, R W, Eeckhoudt, S, Barile, N, Lecut, C, Morel, N, Viollet, B, Jacquet, L-M, Bertrand, L, Sakamoto, K, Vanoverschelde, J-L, Beauloye, C, Horman, S

“…Platelet activation requires sweeping morphologic changes, supported by contraction and remodeling of the platelet actin cytoskeleton. In various other cell…”
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The Ca2+/calmodulin-dependent kinase kinase [beta]-AMP-activated protein kinase-[alpha]1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets by Onselaer, M-B, Oury, C, Hunter, R W, Eeckhoudt, S, Barile, N, Lecut, C, Morel, N, Viollet, B, Jacquet, L-M, Bertrand, L, Sakamoto, K, Vanoverschelde, J-L, Beauloye, C, Horman, S

“…Summary Background Platelet activation requires sweeping morphologic changes, supported by contraction and remodeling of the platelet actin cytoskeleton. In…”
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Implementation of guidelines for seasonal allergic rhinitis: a randomized controlled trial by Bousquet, J., Lund, V. J., Van Cauwenberge, P., Bremard‐Oury, C., Mounedji, N., Stevens, M. T., El‐Akkad, T.

“…Background: Allergic rhinitis is a common disease altering quality of life. Its treatment is well established and guidelines have been proposed. However, their…”
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Targeting of C‐type lectin‐like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides by Delierneux, C., Donis, N., Servais, L., Wéra, O., Lecut, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Schneider, J., Eble, J. A., Lancellotti, P., Oury, C.

“…Essentials CpG oligodeoxynucleotide (ODN) immuotherapeutics cause undesired platelet activating effects. It is crucial to understand the mechanisms of these…”
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ATP‐gated P2X1 ion channels protect against endotoxemia by dampening neutrophil activation by LECUT, C., FACCINETTO, C., DELIERNEUX, C., van OERLE, R., SPRONK, H. M. H., EVANS, R. J., EL BENNA, J., BOURS, V., OURY, C.

“…Background:  In sepsis, extracellular ATP, secreted by activated platelets and leukocytes, may contribute to the crosstalk between hemostasis and inflammation…”
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Left ventricular regional function and maximal exercise capacity in aortic stenosis by Dulgheru, R, Magne, J, Davin, L, Nchimi, A, Oury, C, Pierard, L A, Lancellotti, P

“…The objective assessment of maximal exercise capacity (MEC) using peak oxygen consumption (VO2) measurement may be helpful in the management of asymptomatic…”
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Erratum: Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study by Layios, N, Delierneux, C, Hego, A, Huart, J, Joly, A, Geurts, P, Damas, P, Lecut, C, Gothot, A, Oury, C

“…Declarations Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License…”
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Erratum: Prospective immune profiling in critically ill adults: before, during and after severe sepsis and septic shock by Layios, N, Gosset, C, Delierneux, C, Hego, A, Huart, J, Joly, A, Geurts, P, Damas, P, Oury, C, Gothot, A

“…Declarations Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License…”
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The platelet ATP and ADP receptors by Oury, C, Toth-Zsamboki, E, Vermylen, J, Hoylaerts, M F

“…Adenine nucleotides, ADP and ATP, are coreleased from dense granules during platelet activation, as well as from endothelial cells and damaged red blood cells…”
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ERK2 activation in arteriolar and venular murine thrombosis: platelet receptor GPIb vs. P2X1 by OURY, C., DAENENS, K., HU, H., TOTH‐ZSAMBOKI, E., BRYCKAERT, M., HOYLAERTS, M. F.

“…The functional significance of extracellular signal‐regulated kinase 2 (ERK2) activation was investigated during shear induced human platelet aggregation…”
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The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen by Oury, C, Toth-Zsamboki, E, Thys, C, Tytgat, J, Vermylen, J, Hoylaerts, M F

“…ATP is a potent agonist of the P2X1 ion channel, mediating a rapid, quickly desensitized influx of Ca2+. In hirudinized PRP, containing apyrase, the two stable…”
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TEL Is a Sequence-specific Transcriptional Repressor by Lopez, Rodolphe G., Carron, Clémence, Oury, Cécile, Gardellin, Paola, Bernard, Olivier, Ghysdael, Jacques

“…TEL is a gene frequently involved in specific chromosomal translocations in human leukemia and sarcoma that encodes a member of the ETS family of…”
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P2X1-mediated ERK2 Activation Amplifies the Collagen-induced Platelet Secretion by Enhancing Myosin Light Chain Kinase Activation by Toth-Zsamboki, Emese, Oury, Cécile, Cornelissen, Heidi, De Vos, Rita, Vermylen, Jos, Hoylaerts, Marc F

“…The ATP-gated P2X1 ion channel is the only P2X subtype expressed in human platelets. Via transmission electron microscopy, we found that P2X1 mediates fast,…”
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The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel by Toth-Zsamboki, E, Oury, C, Tytgat, J, Vermylen, J, Hoylaerts, M F

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PB0443 Innovative Non-Isocyanate Polyurethane-Derived Hemocompatible Polymers for Blood-Contacting Medical Devices by Melo, S., Pierrard, A., Detrembleur, C., Jérôme, C., Lancellotti, P., Oury, C.

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ATP Augments von Willebrand Factor-dependent Shear-induced Platelet Aggregation through Ca2+-Calmodulin and Myosin Light Chain Kinase Activation by Oury, Cécile, Sticker, Elsie, Cornelissen, Heidi, De Vos, Rita, Vermylen, Jos, Hoylaerts, Marc F.

“…Shear stress triggers von Willebrand factor (VWF) binding to platelet glycoprotein Ibα and subsequent integrin αIIbβ3-dependent platelet aggregation…”
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COVID-19 andcardiovascular diseases by Haeck, G, Ancion, A, Marechal, P, Oury, C, Lancellotti, P

“…COVID-2019 disease mainly affects the respiratory tract and can progress in severe cases to pneumonia, acute respiratory distress syndrome and multi-organ…”
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Coagulopathies, thrombotic risk and anticoagulation in COVID-19 by Peters, P, Sprynger, M, Lancellotti, P, Oury, C

“…Clinical observations indicate that COVID-19 often provokes coagulopathies, which have been associated with high morbidity and mortality rates. These…”
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