Search Results - "Oukkache, Naoual"
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Development and Efficacy of the Antivenom Specific to Severe Envenomations in Morocco and North Africa: Advancements in Scorpion Envenomation Management
Published in Toxins (01-05-2024)“…Scorpion envenomation poses a global public health issue, with an estimated 1,500,000 cases worldwide annually resulting in 2600 deaths. North Africa,…”
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Induced pathophysiological alterations by the venoms of the most dangerous Moroccan scorpions Androctonus mauretanicus and Buthus occitanus: A comparative pathophysiological and toxic-symptoms study
Published in Human & experimental toxicology (01-01-2022)“…Scorpion envenomation is a serious public health issue. Androctonus mauretanicus (Am) and Buthus occitanus (Bo) are the most dangerous scorpions in Morocco…”
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Neutralization Capacity of Tissue Alterations Caused by the Venoms of the Most Dangerous Scorpions in North Africa Using a Selective Antivenom
Published in Toxins (27-12-2023)“…In North Africa, scorpion stings pose an urgent public health problem, particularly for children with high morbidity and mortality rates. The main species…”
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Anti-Cancer Activity of Buthus occitanus Venom on Hepatocellular Carcinoma in 3D Cell Culture
Published in Molecules (Basel, Switzerland) (29-03-2022)“…Hepatocellular carcinoma (HCC) is the most dominant primary liver cancer, which can be caused by chronic hepatitis virus infections and other environmental…”
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An in-depth exploration of snake venom-derived molecules for drug discovery in advancing antiviral therapeutics
Published in Heliyon (30-09-2024)“…Snake venom is a cocktail and rich source of various bioactive compounds that have been extensively studied for their potential as pharmaceutical agents due to…”
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Assessing the efficacy of monovalent and commercialized antivenoms for neutralizing Moroccan cobra 'Naja haje' venom: A comparative study
Published in Tropical medicine and infectious disease (02-06-2023)“…In Morocco, eight species of venomous snakes belonging to the 'Viperidae' and 'Elapidae' families are responsible for severe envenomation cases. The species…”
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Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus
Published in Life (Basel, Switzerland) (05-05-2023)“…Morocco is known to harbor two of the world's most dangerous scorpion species: the black ( ) and the yellow ( ), responsible for 83% and 14% of severe…”
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Insight into the toxicological and pathophysiological effects of Moroccan vipers' venom: Assessing the efficacy of commercial antivenom for neutralization
Published in Tropical medicine and infectious disease (31-05-2023)“…Morocco is one of the richest countries in biodiversity in the Mediterranean region, especially in its ophidian fauna. In total, there are eight species of…”
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Anti-Cancer Effect of Moroccan Cobra Naja haje Venom and Its Fractions against Hepatocellular Carcinoma in 3D Cell Culture
Published in Toxins (04-06-2021)“…Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of…”
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Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom
Published in FEBS open bio (01-07-2021)“…Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of…”
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Therapeutic potential of snake venom: Toxin distribution and opportunities in deep learning for novel drug discovery
Published in Medicine in drug discovery (01-02-2024)“…[Display omitted] Snake venom is a rich source of bioactive molecules that hold great promise for therapeutic applications. These molecules can be broadly…”
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Comparison between two methods of scorpion venom milking in Morocco
Published in The journal of venomous animals and toxins including tropical diseases (28-03-2013)“…The present study compared two methods used successfully in a large-scale program for the collection of scorpion venoms, namely the milking of adult scorpions…”
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Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes
Published in Toxins (12-06-2014)“…Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such…”
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Consequences of Androctonus mauretanicus and Buthus occitanus scorpion venoms on electrolyte levels in rabbits
Published in Heliyon (01-01-2017)“…Androctonus mauretanicus (A. mauretanicus) and Buthus occitanus (B. occitanus) scorpions, which belong to the Buthidae family, are the most venomous scorpions…”
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Moroccan Naja haje Venom and its Peptides: In Vivo Toxicity and In Vitro Antiproliferative Effect on Hepatocellular Carcinoma HepG2 Cells
Published in International journal of peptide research and therapeutics (28-09-2024)“…Purpose Snake venom, despite its toxicity, presents notable therapeutic potential by specifically targeting tumor cells to inhibit their proliferation or…”
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Epidemiological, clinical, biological and evolutionary profile of scorpion envenomed children under one year to 15 years in the Souss Massa region of Morocco
Published in Toxicon (Oxford) (28-08-2024)“…Morocco is one of the main countries affected in North African with the scorpion envenomations. Faced with the threat, significant morbidity and a major risk…”
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Cobra Venom: From Envenomation Syndromes to Therapeutic Innovations
Published in International journal of peptide research and therapeutics (04-10-2024)“…Purpose of Review Snakebite envenomation, classified as a neglected tropical disease, represents a significant global health threat, particularly in Asia and…”
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Proteome analysis of toxic fractions of Moroccan cobra Naja haje venom using mass spectrometry
Published in International journal of environmental studies (10-07-2024)Get full text
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Effects of Androctonus mauretanicus and Buthus occitanus scorpion venoms on serum electrolytes in injected rabbits: A 24 hour time-course study
Published in Toxicon (Oxford) (01-07-2018)Get full text
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Characterization of Am IT, an anti-insect β-toxin isolated from the venom of scorpion Androctonus mauretanicus
Published in Toxicon (Oxford) (01-07-2018)Get full text
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