Search Results - "Oukkache, Naoual"

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    Development and Efficacy of the Antivenom Specific to Severe Envenomations in Morocco and North Africa: Advancements in Scorpion Envenomation Management by Darkaoui, Bouchra, Hilal, Ines, Khourcha, Soukaina, Lafnoune, Ayoub, Chakir, Salma, Aarab, Ayoub, Moustaghfir, Abdellah, Filali, Ouafaa Aniq, Oukkache, Naoual

    Published in Toxins (01-05-2024)
    “…Scorpion envenomation poses a global public health issue, with an estimated 1,500,000 cases worldwide annually resulting in 2600 deaths. North Africa,…”
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    Journal Article
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    Neutralization Capacity of Tissue Alterations Caused by the Venoms of the Most Dangerous Scorpions in North Africa Using a Selective Antivenom by Darkaoui, Bouchra, Aksim, Mohamed, Aarab, Ayoub, Lafnoune, Ayoub, Khourcha, Soukaina, Cadi, Rachida, Filali, Ouafaa Aniq, Oukkache, Naoual

    Published in Toxins (27-12-2023)
    “…In North Africa, scorpion stings pose an urgent public health problem, particularly for children with high morbidity and mortality rates. The main species…”
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    Journal Article
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    Anti-Cancer Activity of Buthus occitanus Venom on Hepatocellular Carcinoma in 3D Cell Culture by Lafnoune, Ayoub, Lee, Su-Yeon, Heo, Jin-Yeong, Daoudi, Khadija, Darkaoui, Bouchra, Chakir, Salma, Cadi, Rachida, Mounaji, Khadija, Shum, David, Seo, Haeng-Ran, Oukkache, Naoual

    Published in Molecules (Basel, Switzerland) (29-03-2022)
    “…Hepatocellular carcinoma (HCC) is the most dominant primary liver cancer, which can be caused by chronic hepatitis virus infections and other environmental…”
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    An in-depth exploration of snake venom-derived molecules for drug discovery in advancing antiviral therapeutics by Hboub, Hicham, Ben Mrid, Reda, Bouchmaa, Najat, Oukkache, Naoual, El Fatimy, Rachid

    Published in Heliyon (30-09-2024)
    “…Snake venom is a cocktail and rich source of various bioactive compounds that have been extensively studied for their potential as pharmaceutical agents due to…”
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    Journal Article
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    Assessing the efficacy of monovalent and commercialized antivenoms for neutralizing Moroccan cobra 'Naja haje' venom: A comparative study by Khourcha, Soukaina, Hilal, Ines, Elbejjaj, Iatimad, Karkouri, Mehdi, Safi, Amal, Hmyene, Abdelaziz, Oukkache, Naoual

    Published in Tropical medicine and infectious disease (02-06-2023)
    “…In Morocco, eight species of venomous snakes belonging to the 'Viperidae' and 'Elapidae' families are responsible for severe envenomation cases. The species…”
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    Journal Article
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    Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus by Hilal, Ines, Khourcha, Soukaina, Safi, Amal, Hmyene, Abdelaziz, Asnawi, Syafiq, Othman, Iekhsan, Stöcklin, Reto, Oukkache, Naoual

    Published in Life (Basel, Switzerland) (05-05-2023)
    “…Morocco is known to harbor two of the world's most dangerous scorpion species: the black ( ) and the yellow ( ), responsible for 83% and 14% of severe…”
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    Insight into the toxicological and pathophysiological effects of Moroccan vipers' venom: Assessing the efficacy of commercial antivenom for neutralization by Khourcha, Soukaina, Hilal, Ines, Elbejjaj, Iatimad, Karkouri, Mehdi, Safi, Amal, Hmyene, Abdelaziz, Oukkache, Naoual

    Published in Tropical medicine and infectious disease (31-05-2023)
    “…Morocco is one of the richest countries in biodiversity in the Mediterranean region, especially in its ophidian fauna. In total, there are eight species of…”
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    Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom by Daoudi, Khadija, Malosse, Christian, Lafnoune, Ayoub, Darkaoui, Bouchra, Chakir, Salma, Sabatier, Jean‐Marc, Chamot‐Rooke, Julia, Cadi, Rachida, Oukkache, Naoual, Alape‐Girón, Alberto

    Published in FEBS open bio (01-07-2021)
    “…Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of…”
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    Journal Article
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    Therapeutic potential of snake venom: Toxin distribution and opportunities in deep learning for novel drug discovery by Bedraoui, Anas, Suntravat, Montamas, El Mejjad, Salim, Enezari, Salwa, Oukkache, Naoual, Sanchez, Elda E., Galan, Jacob A., El Fatimy, Rachid, Daouda, Tariq

    Published in Medicine in drug discovery (01-02-2024)
    “…[Display omitted] Snake venom is a rich source of bioactive molecules that hold great promise for therapeutic applications. These molecules can be broadly…”
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    Journal Article
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    Comparison between two methods of scorpion venom milking in Morocco by Oukkache, Naoual, Chgoury, Fatima, Lalaoui, Mekki, Cano, Alejandro Alagón, Ghalim, Noreddine

    “…The present study compared two methods used successfully in a large-scale program for the collection of scorpion venoms, namely the milking of adult scorpions…”
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    Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes by Oukkache, Naoual, El Jaoudi, Rachid, Ghalim, Noreddine, Chgoury, Fatima, Bouhaouala, Balkiss, Mdaghri, Naima El, Sabatier, Jean-Marc

    Published in Toxins (12-06-2014)
    “…Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such…”
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    Consequences of Androctonus mauretanicus and Buthus occitanus scorpion venoms on electrolyte levels in rabbits by Daoudi, Khadija, Chgoury, Fatima, Rezzak, Myriam, Bourouah, Oussama, Boussadda, Lotfi, Soukri, Abdelaziz, Sabatier, Jean-Marc, Oukkache, Naoual

    Published in Heliyon (01-01-2017)
    “…Androctonus mauretanicus (A. mauretanicus) and Buthus occitanus (B. occitanus) scorpions, which belong to the Buthidae family, are the most venomous scorpions…”
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    Moroccan Naja haje Venom and its Peptides: In Vivo Toxicity and In Vitro Antiproliferative Effect on Hepatocellular Carcinoma HepG2 Cells by Lafnoune, Ayoub, Chakir, Salma, Darkaoui, Bouchra, Cadi, Rachida, Oukkache, Naoual

    “…Purpose Snake venom, despite its toxicity, presents notable therapeutic potential by specifically targeting tumor cells to inhibit their proliferation or…”
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    Journal Article
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    Epidemiological, clinical, biological and evolutionary profile of scorpion envenomed children under one year to 15 years in the Souss Massa region of Morocco by Darkaoui, Bouchra, El Hidan, Moulay Abdelmounaim, Lafnoune, Ayoub, Arourd, Driss, Belli, Hassan, Cadi, Rachida, Filali, Ouafaa Aniq, Oukkache, Naoual

    Published in Toxicon (Oxford) (28-08-2024)
    “…Morocco is one of the main countries affected in North African with the scorpion envenomations. Faced with the threat, significant morbidity and a major risk…”
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    Journal Article
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    Cobra Venom: From Envenomation Syndromes to Therapeutic Innovations by Lafnoune, Ayoub, Chbel, Asmaa, Darkaoui, Bouchra, Nait Irahal, Imane, Oukkache, Naoual

    “…Purpose of Review Snakebite envenomation, classified as a neglected tropical disease, represents a significant global health threat, particularly in Asia and…”
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