Search Results - "Ouimet, Charles C."

Regional and subcellular distribution of HDAC4 in mouse brain by Darcy, Michael J., Calvin, Kate, Cavnar, Katie, Ouimet, Charles C.

“…Histone deacetylases (HDACs) are part of a system that links epigenetic control of gene expression to a variety of environmental stimuli. Some HDACs, including…”
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Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 by Bibb, James A, Chen, Jingshan, Taylor, Jane R, Svenningsson, Per, Nishi, Akinori, Snyder, Gretchen L, Yan, Zhen, Sagawa, Zachary K, Ouimet, Charles C, Nairn, Angus C, Nestler, Eric J, Greengard, Paul

“…Cocaine enhances dopamine-mediated neurotransmission by blocking dopamine re-uptake at axon terminals. Most dopamine-containing nerve terminals innervate…”
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Spinophilin, a Novel Protein Phosphatase 1 Binding Protein Localized to Dendritic Spines by Allen, Patrick B., Ouimet, Charles C., Greengard, Paul

“…Dendritic spines receive the vast majority of excitatory synaptic contacts in the mammalian brain and are presumed to contain machinery for the integration of…”
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A regulatory role for actin in dendritic spine proliferation by Johnson, Orenda L., Ouimet, Charles C.

“…Dendritic spines are small protrusions that receive 90% of excitatory cortical synapses and are critically important to neural function. Each dendritic spine…”
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Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen by Ouimet, Charles C, Langley-Gullion, Kathryn C, Greengard, Paul

“…DARPP-32, a dopamine and c AMP- regulated phospho protein with an apparent molecular weight of 32 kD, is enriched in dopaminoceptive brain regions. Chief among…”
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Spinophilin Regulates the Formation and Function of Dendritic Spines by Feng, Jian, Yan, Zhen, Ferreira, Adriana, Tomizawa, Kazuhito, Liauw, Jason A., Zhuo, Min, Allen, Patrick B., Ouimet, Charles C., Greengard, Paul

“…Spinophilin, a protein that interacts with actin and protein phosphatase-1, is highly enriched in dendritic spines. Here, through the use of spinophilin…”
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Altered dendritic spine density in animal models of depression and in response to antidepressant treatment by Norrholm, Seth D., Ouimet, Charles C.

“…Olfactory bulbectomy, neonatal clomipramine administration, and maternal deprivation have been employed as animal models of depression. Each model is unique…”
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Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines by Ouimet, Charles C., Katona, István, Allen, Patrick, Freund, Tamás F., Greengard, Paul

“…Spinophilin is an actin binding protein that positions protein phosphatase 1 next to its substrates in dendritic spines. It contains a single PDZ domain and…”
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Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus by Norrholm, Seth D., Ouimet, Charles C.

“…The density of dendritic spines, the postsynaptic sites of most excitatory synapses, increases during the first 2 postnatal months in rat hippocampus…”
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Protein synthesis is necessary for dendritic spine proliferation in adult brain slices by Johnson, Orenda L., Ouimet, Charles C.

“…Dendritic spines, small protrusions from dendritic shafts, receive most of the excitatory synapses in cortical regions. Spines are highly plastic structures…”
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The DARPP-32/protein phosphatase-1 cascade: a model for signal integration by Greengard, Paul, Nairn, Angus C, Girault, Jean-Antoine, Ouimet, Charles C, Snyder, Gretchen L, Fisone, Gilberto, Allen, Patrick B, Fienberg, Allen, Nishi, Akinori

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Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain by Ouimet, C C, LaMantia, A S, Goldman-Rakic, P, Rakic, P, Greengard, P

“…The localization of DARPP-32, a dopamine and cAMP-regulated phosphoprotein, has been studied in monkey brain by immunocytochemistry. This study indicates that…”
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DARPP-32, a dopamine and cyclic AMP-regulated phosphoprotein, is present in corticothalamic neurons of the rat cingulate cortex by Ouimet, C C

“…DARPP-32 immunocytochemistry and retrograde axonal labeling were combined to determine whether DARPP-32-containing neurons of the rat anterior cingulate cortex…”
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The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1 by Greengard, Paul, Nairn, Angus C, Girault, Jean-Antoine, Ouimet, Charles C, Snyder, Gretchen L, Fisone, Gilberto, Allen, Patrick B, Fienberg, Allen, Nishi, Akinori

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The α and γ1 Isoforms of Protein Phosphatase 1 are Highly and Specifically Concentrated in Dendritic Spines by Ouimet, Charles C., Edgar F. da Cruze e Silva, Greengard, Paul

“…Protein phosphatase 1 (PP1) is a highly conserved enzyme that has been implicated in diverse biological processes in the brain as well as in nonneuronal…”
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Differential expression of protein phosphatase 1 isoforms in mammalian brain by da Cruz e Silva, EF, Fox, CA, Ouimet, CC, Gustafson, E, Watson, SJ, Greengard, P

“…Rat cDNAs encoding neuronal isoforms of protein phosphatase 1 (PP1) were isolated and their primary structures elucidated. The derived amino acid sequences…”
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Impaired conditioned taste aversion learning in spinophilin knockout mice by Stafstrom-Davis, C A, Ouimet, C C, Feng, J, Allen, P B, Greengard, P, Houpt, T A

“…Plasticity in dendritic spines may underlie learning and memory. Spinophilin, a protein enriched in dendritic spines, has the properties of a scaffolding…”
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Immunocytochemistry of Brain Phosphoproteins, Protein Kinases, and Phosphatases by Ouimet, Charles C.

“…Phosphoproteins and their associated kinases and phosphatases play a major role in second messenger signal cascades in neurons. Immunocytochemical studies have…”
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DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization by Ouimet, CC, Miller, PE, Hemmings, HC, Jr, Walaas, SI, Greengard, P

“…Immunocytochemical studies have been carried out to determine the regional and cellular distribution of DARPP-32, a protein the phosphorylation of which can be…”
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Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain by Ouimet, CC, Wang, JK, Walaas, SI, Albert, KA, Greengard, P

“…The localization of MARCKS (myristoylated, alanine-rich C-kinase substrate), a major specific substrate for protein kinase C, has been studied in the rat…”
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