Search Results - "Ouellet, A"

Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration by Cherif, Hosni, Mannarino, Matthew, Pacis, Alain Sarabia, Ragoussis, Jiannis, Rabau, Oded, Ouellet, Jean A, Haglund, Lisbet

“…In this study, we used single-cell transcriptomic analysis to identify new specific biomarkers for nucleus pulposus (NP) and inner annulus fibrosis (iAF)…”
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Senotherapeutic drugs for human intervertebral disc degeneration and low back pain by Cherif, Hosni, Bisson, Daniel G, Mannarino, Matthew, Rabau, Oded, Ouellet, Jean A, Haglund, Lisbet

“…Cellular senescence is a contributor to intervertebral disc (IVD) degeneration and low back pain. Here, we found that RG-7112, a potent mouse double-minute two…”
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Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function by Seminowicz, David A, Wideman, Timothy H, Naso, Lina, Hatami-Khoroushahi, Zeinab, Fallatah, Summaya, Ware, Mark A, Jarzem, Peter, Bushnell, M Catherine, Shir, Yoram, Ouellet, Jean A, Stone, Laura S

“…Chronic pain is associated with reduced brain gray matter and impaired cognitive ability. In this longitudinal study, we assessed whether neuroanatomical and…”
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Partial recovery of abnormal insula and dorsolateral prefrontal connectivity to cognitive networks in chronic low back pain after treatment by Čeko, Marta, Shir, Yoram, Ouellet, Jean A., Ware, Mark A., Stone, Laura S., Seminowicz, David A.

“…We previously reported that effective treatment of chronic low back pain (CLBP) reversed abnormal brain structure and functional MRI (fMRI) activity during…”
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EP16.27: Acceptability and tolerability of magnetic resonance angiography as compared to Doppler ultrasound in the third trimester of pregnancy by Vanderweyen, D., Wilk, C., Philibert, M., Gillet, V., Whittingstall, K., Ouellet, A.

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Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin by Mannarino, Matthew, Cherif, Hosni, Li, Li, Sheng, Kai, Rabau, Oded, Jarzem, Peter, Weber, Michael H, Ouellet, Jean A, Haglund, Lisbet

“…There is an increased level of senescent cells and toll-like teceptor-1, -2, -4, and -6 (TLR) expression in degenerating intervertebral discs (IVDs) from back…”
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Functional Outcomes After Hip Fracture in Independent Community‐Dwelling Patients by Ouellet, Jennifer A., Ouellet, Gregory M., Romegialli, Alison M., Hirsch, Marilyn, Berardi, Lisa, Ramsey, Christine M., Cooney Jr, Leo M., Walke, Lisa M.

“…OBJECTIVES To determine predictors of new activities of daily living (ADLs) disability and worsened mobility disability and secondarily increased daily care…”
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Acute mechanical injury of the human intervertebral disc: link to degeneration and pain by Alkhatib, B, Rosenzweig, D H, Krock, E, Roughley, P J, Beckman, L, Steffen, T, Weber, M H, Ouellet, J A, Haglund, L

“…Excessive mechanical loading or acute trauma to intervertebral discs (IVDs) is thought to contribute to degeneration and pain. However, the exact mechanisms by…”
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EP15.27: Rare case of fetal esophageal duplication cyst discovered in pregnancy: a case report by Bérubé, G., Hardy, I., Ouellet, A., Raîche, E., Roy‐Lacroix, M.

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Predicting Acute Postoperative Pain Trajectories and Long-Term Outcomes of Adolescents after Spinal Fusion Surgery by Pagé, M. Gabrielle, Ouellet, Jean A., Ingelmo, Pablo, Li, Mandy M.J., Ocay, Don Daniel, Ferland, Catherine E.

“…Objectives. Acute pain trajectories are associated with long-term outcomes such as persistent pain and functional disability in adults. However, there are…”
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Thermoreversible hyaluronan-hydrogel and autologous nucleus pulposus cell delivery regenerates human intervertebral discs in an ex vivo, physiological organ culture model by Rosenzweig, D H, Fairag, R, Mathieu, A P, Li, L, Eglin, D, D'Este, M, Steffen, T, Weber, M H, Ouellet, J A, Haglund, L

“…Numerous studies show promise for cell-based tissue engineering strategies aiming to repair painful intervertebral disc (IVD) degeneration. However, clinical…”
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Adolescent idiopathic scoliosis: evaluating perioperative back pain through a simultaneous morphological and biomechanical approach by St-Georges, Maxime, Teles, Alisson R, Rabau, Oded, Saran, Neil, Ouellet, Jean A, Ferland, Catherine E

“…Adolescent idiopathic scoliosis (AIS) has been associated with diminished postural stability and a greater prevalence of back pain. Currently, the literature…”
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P17.07: Chorioangiomas with signs of fetal compromise on ultrasound evaluation: a case series by Hardy, I., Bérubé, G., Raîche, E., Roy‐Lacroix, M., Ouellet, A.

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EP27.38: Is the use of the ScanTrainer ultrasound simulator relevant to the continuous professional development of obstetricians and gynecologists? by Hardy, I., Gosselin, E., Bertholet, C., Raîche, E., Roy‐Lacroix, M., Ouellet, A.

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A roadmap to surgery in osteogenesis imperfecta: results of an international collaboration of patient organizations and interdisciplinary care teams by Sakkers, Ralph J, Montpetit, Kathleen, Tsimicalis, Argerie, Wirth, Thomas, Verhoef, Marjolein, Hamdy, Reginald, Ouellet, Jean A, Castelein, Rene M, Damas, Chantal, Janus, Guus J, Nijhuis, Wouter H, Panzeri, Leonardo, Paveri, Simona, Mekking, Dagmar, Thorstad, Kelly, Kruse, Richard W

“…Background and purpose - Involvement of patient organizations is steadily increasing in guidelines for treatment of various diseases and conditions for better…”
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Critical Doping for the Onset of Fermi-Surface Reconstruction by Charge-Density-Wave Order in the Cuprate Superconductor La2−xSrxCuO4 by Badoux, S, Afshar, S A A, Michon, B, Ouellet, A, tier, S, LeBoeuf, D, Croft, T P, Lester, C, Hayden, S M, Takagi, H, Yamada, K, Graf, D, Doiron-Leyraud, N, Taillefer, Louis

“…The Seebeck coefficient S of the cuprate superconductor La2−xSrxCuO4 (LSCO) was measured in magnetic fields large enough to access the normal state at low…”
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Senolytic Combination Treatment Is More Potent Than Single Drugs in Reducing Inflammatory and Senescence Burden in Cells from Painful Degenerating IVDs by Mannarino, Matthew, Wu-Martinez, Oliver, Sheng, Kai, Li, Li, Navarro-Ramirez, Rodrigo, Jarzem, Peter, Ouellet, Jean A., Cherif, Hosni, Haglund, Lisbet

“…Background: Low back pain is a global health problem directly related to intervertebral disc (IVD) degeneration. Senolytic drugs (RG-7112 and o-Vanillin)…”
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Comparative analysis in continuous expansion of bovine and human primary nucleus pulposus cells for tissue repair applications by Rosenzweig, D H, Tremblay Gravel, J, Bisson, D, Ouellet, J A, Weber, M H, Haglund, L

“…Autologous NP cell implantation is a potential therapeutic avenue for intervertebral disc (IVD) degeneration. However, monolayer expansion of cells isolated…”
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Dynamic loading, matrix maintenance and cell injection therapy of human intervertebral discs cultured in a bioreactor by Rosenzweig, D H, Gawri, R, Moir, J, Beckman, L, Eglin, D, Steffen, T, Roughley, P J, Ouellet, J A, Haglund, L

“…Low back pain originating from intervertebral disc (IVD) degeneration affects the quality of life for millions of people, and it is a major contributor to…”
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Validation of the Critical-Care Pain Observation Tool (CPOT) in pediatric patients undergoing orthopedic surgery by Li, Mandy M. J., Ocay, Don Daniel, Larche, Cynthia L., Vickers, Kelsey, Saran, Neil, Ouellet, Jean A., Gélinas, Céline, Ferland, Catherine E.

“…Postoperative pain cannot be measured accurately among many children with intellectual and developmental disabilities, resulting in underrecognition or delay…”
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