Search Results - "Oudejans, Cees B. M."

The effect of maternal NODAL on STOX1 expression in extravillous trophoblasts is mediated by IGF1 by Visser, Allerdien, Beijer, Maarten, Oudejans, Cees B M, van Dijk, Marie

“…The number of molecules identified to be involved in communication between placenta and decidua is fast expanding. Previously, we showed that NODAL expressed…”
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Calculating the fetal fraction for noninvasive prenatal testing based on genome-wide nucleosome profiles by Straver, Roy, Oudejans, Cees B. M., Sistermans, Erik A., Reinders, Marcel J. T.

“…Objective While large fetal copy number aberrations can generally be detected through sequencing of DNA in maternal blood, the reliability of tests depends on…”
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Methotrexate Provokes Disparate Folate Metabolism Gene Expression and Alternative Splicing in Ex Vivo Monocytes and GM-CSF- and M-CSF-Polarized Macrophages by Muller, Ittai B, Lin, Marry, Jonge, Robert de, Will, Nico, López-Navarro, Baltasar, Laken, Conny van der, Struys, Eduard A, Oudejans, Cees B M, Assaraf, Yehuda G, Cloos, Jacqueline, Puig-Kröger, Amaya, Jansen, Gerrit

“…Macrophages constitute important immune cell targets of the antifolate methotrexate (MTX) in autoimmune diseases, including rheumatoid arthritis. Regulation of…”
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Cardiac Expression of Deiodinase type 3 (Dio3) Following Myocardial Infarction Is Associated With the Induction of a Pluripotency microRNA Signature from the Dlk1-Dio3 Genomic Region by Janssen, Rob, Zuidwijk, Marian, Muller, Alice, Mulders, Joyce, Oudejans, Cees B.M, Simonides, Warner S

“…The adult heart has almost completely lost the proliferative potential of the fetal heart. Instead, loss of cardiomyocytes due to myocardial infarction (MI)…”
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Detection of the Placental Epigenetic Signature of the Maspin Gene in Maternal Plasma by Stephen S. C. Chim, Yu K. Tong, Rossa W. K. Chiu, Lau, Tze K., Leung, Tse N., Lisa Y. S. Chan, Cees B. M. Oudejans, Ding, Chunming, Y. M. Dennis Lo

“…The discovery of fetal DNA in the plasma of pregnant women has opened up new approaches for noninvasive prenatal diagnosis and monitoring. Up to now, the lack…”
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Transcription factor STOX1A promotes mitotic entry by binding to the CCNB1 promotor by Abel, Daan van, Abdul-Hamid, Omar, Dijk, Marie van, Oudejans, Cees B M

“…In this study we investigated the involvement of the transcription factor STOX1A in the regulation of the cell cycle. We found that several major cell cycle…”
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WISECONDOR: detection of fetal aberrations from shallow sequencing maternal plasma based on a within-sample comparison scheme by Straver, Roy, Sistermans, Erik A, Holstege, Henne, Visser, Allerdien, Oudejans, Cees B M, Reinders, Marcel J T

“…Genetic disorders can be detected by prenatal diagnosis using Chorionic Villus Sampling, but the 1:100 chance to result in miscarriage restricts the use to…”
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Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing by Yu, Stephanie C. Y., Chan, K. C. Allen, Zheng, Yama W. L., Jiang, Peiyong, Liao, Gary J. W., Sun, Hao, Akolekar, Ranjit, Leung, Tak Y., Go, Attie T. J. I., van Vugt, John M. G., Minekawa, Ryoko, Oudejans, Cees B. M., Nicolaides, Kypros H., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Noninvasive prenatal testing using fetal DNA in maternal plasma is an actively researched area. The current generation of tests using massively parallel…”
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Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing by Chen, Eric Z, Chiu, Rossa W K, Sun, Hao, Akolekar, Ranjit, Chan, K C Allen, Leung, Tak Y, Jiang, Peiyong, Zheng, Yama W L, Lun, Fiona M F, Chan, Lisa Y S, Jin, Yongjie, Go, Attie T J I, Lau, Elizabeth T, To, William W K, Leung, Wing C, Tang, Rebecca Y K, Au-Yeung, Sidney K C, Lam, Helena, Kung, Yu Y, Zhang, Xiuqing, van Vugt, John M G, Minekawa, Ryoko, Tang, Mary H Y, Wang, Jun, Oudejans, Cees B M, Lau, Tze K, Nicolaides, Kypros H, Lo, Y M Dennis

“…Massively parallel sequencing of DNA molecules in the plasma of pregnant women has been shown to allow accurate and noninvasive prenatal detection of fetal…”
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SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells by van Abel, Daan, Hölzel, Dennis R, Jain, Shushant, Lun, Fiona M F, Zheng, Yama W L, Chen, Eric Z, Sun, Hao, Chiu, Rossa W K, Lo, Y M Dennis, van Dijk, Marie, Oudejans, Cees B M

“…In this study, we performed a genome-wide search for effector genes bound by STOX1A, a winged helix transcription factor recently demonstrated to be involved…”
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The STOX1 genotype associated with pre-eclampsia leads to a reduction of trophoblast invasion by α-T-catenin upregulation by van Dijk, Marie, van Bezu, Jan, van Abel, Daan, Dunk, Caroline, Blankenstein, Marinus A., Oudejans, Cees B.M., Lye, Stephen J.

“…By using complementary in vitro and ex vivo approaches, we show that the risk allele (Y153H) of the pre-eclampsia susceptibility gene STOX1 negatively…”
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The association between blood MxA mRNA and long-term disease activity in early multiple sclerosis by Coerver, Eline M. E., Strijbis, Eva M. M., Petzold, Laura F., Van Kempen, Zoé L. E., Jasperse, Bas, Barkhof, Frederik, Oudejans, Cees B. M., Uitdehaag, Bernard M. J., Teunissen, Charlotte E., Killestein, Joep

“…Background Myxovirus resistance protein A (MxA) is a protein that is upregulated by interferon-beta. Homeostatic MxA mRNA levels are potentially correlated…”
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Mutations within the LINC-HELLP non-coding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation by van Dijk, Marie, Visser, Allerdien, Buabeng, Kwadwo M L, Poutsma, Ankie, van der Schors, Roel C, Oudejans, Cees B M

“…LINC-HELLP, showing chromosomal linkage with the pregnancy-specific HELLP syndrome in Dutch families, reduces differentiation from a proliferative to an…”
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MicroRNA 214 Is a Potential Regulator of Thyroid Hormone Levels in the Mouse Heart Following Myocardial Infarction, by Targeting the Thyroid-Hormone-Inactivating Enzyme Deiodinase Type III by Janssen, Rob, Zuidwijk, Marian J, Muller, Alice, van Mil, Alain, Dirkx, Ellen, Oudejans, Cees B M, Paulus, Walter J, Simonides, Warner S

“…Cardiac thyroid-hormone signaling is a critical determinant of cellular metabolism and function in health and disease. A local hypothyroid condition within the…”
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Maternal plasma bisulfite DNA sequencing: tomorrow starts today by Oudejans, Cees B M

“…In other words, when preeclampsia or HELLP with permanent changes in the nature and number of epigenomic marks (mostly 5-methylcytosine) resets the maternal…”
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Direct downregulation of CNTNAP2 by STOX1A is associated with Alzheimer's disease by van Abel, Daan, Michel, Omar, Veerhuis, Rob, Jacobs, Marlies, van Dijk, Marie, Oudejans, Cees B M

“…STOX1A is a transcription factor which is functionally and structurally similar to the forkhead box protein family. STOX1A has been shown to be associated with…”
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Genetics of preeclampsia : paradigm shifts by OUDEJANS, Cees B. M, VAN DIJK, Marie, OOSTERKAMP, Marjet, LACHMEIJER, Augusta, BLANKENSTEIN, Marinus A

“…Segregation of preeclampsia into early-onset, placental and late-onset, maternal subtypes along with the acknowledgement of the contribution of epigenetics in…”
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Non-invasive aneuploidy detection using free fetal DNA and RNA in maternal plasma: recent progress and future possibilities by Go, Attie T J I, van Vugt, John M G, Oudejans, Cees B M

“…Cell-free fetal DNA (cff DNA) and RNA can be detected in maternal plasma and used for non-invasive prenatal diagnostics. Recent technical advances have led to…”
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STOX1: Key Player in Trophoblast Dysfunction Underlying Early Onset Preeclampsia with Growth Retardation by van Dijk, Marie, Oudejans, Cees B. M.

“…Currently, only two preeclampsia susceptibility genes (ACVR2A, STOX1) have been identified within confirmed regions with significant genome-wide linkage,…”
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Measurement of Allelic-Expression Ratios in Trisomy 21 Placentas by Quencher Extension of Heterozygous Samples Identified by Partially Denaturing HPLC by Go, Attie T.J.I, Visser, Allerdien, Betsalel, Ofir T, van Vugt, John M.G, Blankenstein, Marinus A, Oudejans, Cees B.M

“…Measuring the allelic ratios of placental transcripts in maternal plasma permits noninvasive prenatal detection of chromosomal aneuploidy. Current methods,…”
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