Search Results - "Ouchi, Mutsuko"

BRCA1 affects global DNA methylation through regulation of DNMT1 by Shukla, Vivek, Coumoul, Xavier, Lahusen, Tyler, Wang, Rui-Hong, Xu, Xiaoling, Vassilopoulos, Athanassios, Xiao, Cuiying, Lee, Mi-Hye, Man, Yan-Gao, Ouchi, Mutsuko, Ouchi, Toru, Deng, Chu-Xia

“…Global DNA hypomethylation at CpG islands coupled with local hypermethylation is a hallmark for breast cancer, yet the mechanism underlying this change remains…”
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BRCA1 Phosphorylation by Aurora-A in the Regulation of G2 to M Transition by Ouchi, Mutsuko, Fujiuchi, Nobuko, Sasai, Kaori, Katayama, Hiroshi, Minamishima, Yohji A, Ongusaha, Pat P, Deng, Chuxia, Sen, Subrata, Lee, Sam W, Ouchi, Toru

“…Aurora-A/BTAK/STK15 localizes to the centrosome in the G 2 -M phase, and its kinase activity regulates the G 2 to M transition of the cell cycle. Previous…”
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Physiological and oncogenic Aurora-A pathway by Saeki, Toshiaki, Ouchi, Mutsuko, Ouchi, Toru

“…Aurora family of protein kinases have emerged as crucial factors of, not only mitosis and cytokinesis, but also human carcinogenesis. Among these family…”
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Collaboration of Signal Transducer and Activator of Transcription 1 (STAT1) and BRCA1 in Differential Regulation of IFN-γ Target Genes by Ouchi, Toru, Lee, Sam W., Ouchi, Mutsuko, Aaronson, Stuart A., Horvath, Curt M.

“…Most of the activities of IFN-γ are the result of STAT1-mediated transcriptional responses. In this study, we show that the BRCA1 tumor suppressor acts in…”
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Distinct DNA damage determines differential phosphorylation of Chk2 by Ouchi, Mutsuko, Ouchi, Toru

“…Checkpoint kinase 2 (Chk2) has been implicated in DNA damage signaling. By using BJ human fibroblasts, HCT116 colorectal cancer cells and HeLa cervical cancer…”
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Abstract 3216: H2AX is a novel prognostic marker of breast cancer by Katsuta, Eriko, Ouchi, Mutsuko, Ouchi, Toru, Takabe, Kazuaki

“…Abstract INTRODUCTION: Phosphorylation of histone variant H2AX, termed gamma-H2AX, is well known for its role in DNA damage repair. On the other hand, clinical…”
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Role of IFI16 in DNA damage and checkpoint by Ouchi, Mutsuko, Ouchi, Toru

“…IFI16 is a member of the HIN-200 family (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeat) that contains a DNA binding domain, a…”
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Tumor suppression by resistant maltodextrin, Fibersol-2 by So, Eui Young, Ouchi, Mutsuko, Cuesta-Sancho, Sara, Olson, Susan Losee, Reif, Dirk, Shimomura, Kazuhiro, Ouchi, Toru

“…Resistant maltodextrin Fibersol-2 is a soluble and fermentable dietary fiber that is Generally Recognized As Safe (GRAS) in the United States. We tested…”
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Deregulation of BRCA1 Leads to Impaired Spatiotemporal Dynamics of γ-H2AX and DNA Damage Responses in Huntington’s Disease by Jeon, Gye Sun, Kim, Ki Yoon, Hwang, Yu Jin, Jung, Min-Kyung, An, Sungkwan, Ouchi, Mutsuko, Ouchi, Toru, Kowall, Neil, Lee, Junghee, Ryu, Hoon

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder of mid-life onset characterized by involuntary movements and progressive…”
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BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition by Ouchi, Mutsuko, Fujiuchi, Nobuko, Sasai, Kaori, Katayama, Hiroshi, Minamishima, Yohji A., Ongusaha, Pat P., Deng, Chuxia, Sen, Subrata, Lee, Sam W., Ouchi, Toru

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Regulation of ATM/DNA-PKcs Phosphorylation by BRCA1-Associated BAAT1 by Ouchi, Mutsuko, Ouchi, Toru

“…BRCA1 has been implicated in the DNA damage pathway and regulation of genome stability, however, it does not contain intrinsic catalytic activity to repair the…”
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Deregulation of BRCA1 Leads to Impaired Spatiotemporal Dynamics of [gamma]-H2AX and DNA Damage Responses in Huntington's Disease by Jeon, Gye Sun, Kim, Ki Yoon, Hwang, Yu Jin, Jung, Min-kyung, An, Sungkwan, Ouchi, Mutsuko, Ouchi, Toru, Kowall, Neil, Lee, Junghee, Ryu, Hoon

“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder of mid-life onset characterized by involuntary movements and progressive…”
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Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpint by phosphorylation of p53 SER37 by Tawara, Hideyuki

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Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37 by Tawara, Hideyuki, Fujiuchi, Nobuko, Sironi, Juan, Martin, Sarah, Aglipay, Jason, Ouchi, Mutsuko, Taga, Makoto, Chen, Phang-Lang, Ouchi, Toru

“…Our previous results that IFI16 is involved in p53 transcription activity under conditions of ionizing radiation (IR), and that the protein is frequently lost…”
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