Search Results - "Ou Lingling"

Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms by Ou, Lingling, Song, Bin, Liang, Huimin, Liu, Jia, Feng, Xiaoli, Deng, Bin, Sun, Ting, Shao, Longquan

“…Due to their unique physicochemical properties, graphene-family nanomaterials (GFNs) are widely used in many fields, especially in biomedical applications…”
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Editorial: Regulation of tumor immune surveillance: drug discovery and mechanisms by Zhang, Yuwei, Chen, Haofan, Ou, Lingling

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Nanomaterials and hepatic disease: toxicokinetics, disease types, intrinsic mechanisms, liver susceptibility, and influencing factors by Sun, Ting, Kang, Yiyuan, Liu, Jia, Zhang, Yanli, Ou, Lingling, Liu, Xiangning, Lai, Renfa, Shao, Longquan

“…The widespread use of nanomaterials (NMs) has raised concerns that exposure to them may introduce potential risks to the human body and environment. The liver…”
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TCL1A-expressing B cells are critical for tertiary lymphoid structure formation and the prognosis of oral squamous cell carcinoma by Xie, Wenqiang, Lu, Jinjin, Chen, Yichen, Wang, Xi, Lu, Huanzi, Li, Qunxing, Jin, Nianqiang, He, Jiankang, Ou, Lingling, Ni, Jia, Shen, Yuqin, Shao, Longquan

“…Oral squamous cell carcinoma (OSCC) is a malignant tumor with a poor prognosis. Traditional treatments have limited effectiveness. Regulation of the immune…”
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The construction and analysis of tricarboxylic acid cycle related prognostic model for cervical cancer by Chen, Guanqiao, Hong, Xiaoshan, He, Wanshan, Ou, Lingling, Chen, Bin, Zhong, Weitao, Lin, Yu, Luo, Xiping

“…Cervical cancer (CC) is the fourth most common malignant tumor in term of in incidence and mortality among women worldwide. The tricarboxylic acid (TCA) cycle…”
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Targeting regulatory T cells for immunotherapy in melanoma by Huang, Lili, Guo, Yeye, Liu, Shujing, Wang, Huaishan, Zhu, Jinjin, Ou, Lingling, Xu, Xiaowei

“…Regulatory T cells (Tregs) are essential in the maintenance of immunity, and they are also a key to immune suppressive microenvironment in solid tumors. Many…”
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Central neurotoxicity induced by the instillation of ZnO and TiO2 nanoparticles through the taste nerve pathway by Chen, Aijie, Liang Huimin, Liu, Jia, Ou Lingling, Wei, Limin, Wu Junrong, Lai, Xuan, Han, Xue, Shao Longquan

“…Aim: To explore whether nanoparticles (NPs) can be transported into the CNS via the taste nerve pathway. Materials & methods: ZnO and TiO2 NPs were…”
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Small extracellular vesicles‐based cell‐free strategies for therapy by Guo, Yeye, Wang, Huaishan, Huang, Lili, Ou, Lingling, Zhu, Jinjin, Liu, Shujing, Xu, Xiaowei

“…Small extracellular vesicles (sEVs) are extracellular nanovesicles that contain bioactive proteins, lipids, RNA, and DNA. A variety of biological process is…”
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Potential Links between Cytoskeletal Disturbances and Electroneurophysiological Dysfunctions Induced in the Central Nervous System by Inorganic Nanoparticles by Kang, Yiyuan, Liu, Jia, Song, Bin, Feng, Xiaoli, Ou, Lingling, Wei, Limin, Lai, Xuan, Shao, Longquan

“…Inorganic nanomaterials have been widely applied in biomedicine. However, several studies have noted that inorganic nanoparticles can enter the brain and…”
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Dichotomous and stable gamma delta T-cell number and function in healthy individuals by Ou, Lingling, Wang, Huaishan, Liu, Qin, Zhang, Jie, Lu, Hezhe, Luo, Liangping, Shi, Changzheng, Lin, Shaoqiang, Dong, Liyun, Guo, Yeye, Huang, Lili, Zhu, Jinjin, Yin, Xiangfan, Huang, Alexander C, Karakousis, Giorgos, Schuchter, Lynn, Amaravadi, Ravi, Zheng, Cathy, Fan, Yi, Guo, Wei, Xu, Xiaowei

“…BackgroundGamma-delta (γδ) T lymphocytes are primed to potently respond to pathogens and transformed cells by recognizing a broad range of antigens. However,…”
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Preclinical platforms to study therapeutic efficacy of human γδ T cells by Ou, Lingling, Wang, Huaishan, Huang, Hui, Zhou, Zhiyan, Lin, Qiang, Guo, Yeye, Mitchell, Tara, Huang, Alexander C., Karakousis, Giorgos, Schuchter, Lynn, Amaravadi, Ravi, Guo, Wei, Salvino, Joseph, Herlyn, Meenhard, Xu, Xiaowei

“…Background Gamma delta (γδ) T lymphocytes are promising candidate for adoptive T cell therapy, however, their treatment efficacy is not satisfactory. Vδ2…”
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The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis by Ou, Lingling, Lin, Shaoqiang, Song, Bin, Liu, Jia, Lai, Renfa, Shao, Longquan

“…Graphene-based materials (GBMs) are widely used in many fields, including biomedicine. To date, much attention had been paid to the potential unexpected toxic…”
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Hepatic distribution and toxicity of zirconia nanoparticles in vivo and in vitro by Sun, Ting, Liu, Xiangning, Zhan, Xiaozhen, Ou, Lingling, Lai, Renfa

“…[Display omitted] •We investigated the hepatic biodistribution and toxicological effects of ZrO2-NPs after intravenous administration in vivo and the…”
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Novel Carbon Quantum Dots Precisely Trigger Ferroptosis in Cancer Cells through Antioxidant Inhibition Synergistic Nanocatalytic Activity by Jin, Nianqiang, Wang, Zilin, Yin, Chengcheng, Bu, Wenhuan, Jin, Nuo, Ou, Lingling, Xie, Wenqiang, He, Jiankang, Lai, Xuan, Shao, Longquan

“…High levels of glutathione (GSH) are an important characteristic of malignant tumors and a significant cause of ineffective treatment and multidrug resistance…”
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MicroRNA‐214 contributes to regulation of necroptosis via targeting ATF4 in diabetes‐associated periodontitis by Ou, Lingling, Sun, Ting, Cheng, Yaodong, Huang, Linwei, Zhan, Xiaozhen, Zhang, Peng, Yang, Junjie, Zhang, Ye, Zhou, Zhiying

“…Diabetes and periodontal diseases have a mutual promoting relationship that induces severe tissue damage and cell death. The potential roles of microRNAs…”
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Unveiling Therapeutic Opportunities with Melanoma Patient-derived Organoid Models by Goncalves, Beatriz, Liu, Shujing, Zhang, Xiaogang, Fan, Andrew, Ou, Lingling, Xu, Xiaowei

“…With the development of immunotherapy, there is an ongoing need to develop models that can recapitulate the tumor microenvironment of native tumors. While…”
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Graphene-Based Material-Mediated Immunomodulation in Tissue Engineering and Regeneration: Mechanism and Significance by Ou, Lingling, Tan, Xiner, Qiao, Shijia, Wu, Junrong, Su, Yuan, Xie, Wenqiang, Jin, Nianqiang, He, Jiankang, Luo, Ruhui, Lai, Xuan, Liu, Wenjing, Zhang, Yanli, Zhao, Fujian, Liu, Jia, Kang, Yiyuan, Shao, Longquan

“…Tissue engineering and regenerative medicine hold promise for improving or even restoring the function of damaged organs. Graphene-based materials (GBMs) have…”
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Functionalization of SF/HAP Scaffold with GO-PEI-miRNA inhibitor Complexes to Enhance Bone Regeneration through Activating Transcription Factor 4 by Ou, Lingling, Lan, Yong, Feng, Zhiqiang, Feng, Longbao, Yang, Junjie, Liu, Yu, Bian, Liming, Tan, Jiali, Lai, Renfa, Guo, Rui

“…Evidence indicates that microRNAs (miRNAs) play vital roles in regulating osteogenic differentiation and bone formation. : Here, we show that a…”
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Functionalization of SF/HAP Scaffold with GO-PEI-miRNA inhibitor Complexes to Enhance Bone Regeneration through Activating Transcription Factor 4: Erratum by Ou, Lingling, Lan, Yong, Feng, Zhiqiang, Feng, Longbao, Yang, Junjie, Liu, Yu, Bian, Liming, Tan, Jiali, Lai, Renfa, Guo, Rui

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PD-L1 in Melanoma and Extracellular Vesicles Promotes Local and Regional Immune Suppression through M2-like Macrophage Polarization by Huang, Lili, Yang, Jingbo, Zhu, Jinjin, Wang, Huaishan, Dong, Liyun, Guo, Yeye, Chen, Yeqing, Zhang, Feng, Xu, David J., Ou, Lingling, Xu, Jaiden R., Guan, Lei, Doan, Quoc D., Fan, Andrew Y., Zhong, Wenqun, Ko, Jina, Liang, Chengyu, Herlyn, Meenhard, Guo, Wei, Xu, Xiaowei, Liu, Shujing

“…Tumor-associated macrophages (TAMs) play dual roles in tumor progression. TAMs are known to induce programmed death ligand-1 (PD-L1) expression in cancer…”
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