Search Results - "Ou‐Yang, Qiu‐Geng"

Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro by liu, Qian, Ou‐Yang, Qiu‐Geng, Lin, Qian‐Meng, Lu, Xiang‐Ran, Ma, Ya‐Qing, Li, Ying‐Hui, Xu, Ren‐Ai, Lin, Dong‐dong, Hu, Guo‐Xin, Cai, Jian‐Ping

“…Saxagliptin is a dipeptidyl peptidase 4 (DPP‐4) inhibitor widely used in patients with type 2 diabetes. It can increase the amount of insulin after meals and…”
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The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer by Li, Dan-Ni, Yang, Cheng-Cheng, Li, Jin, Ou Yang, Qiu-Geng, Zeng, Lv-Tao, Fan, Guo-Qing, Liu, Teng-Hui, Tian, Xin-Yuan, Wang, Jing-Jing, Zhang, He, Dai, Da-Peng, Cui, Ju, Cai, Jian-Ping

“…MutT Homolog 1 (MTH1) is a mammalian 8-oxodGTPase for sanitizing oxidative damage to the nucleotide pool. Nudix type 5 (NUDT5) also sanitizes 8-oxodGDP in the…”
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Investigation of the Inhibitory Effect of Simvastatin on the Metabolism of Lidocaine Both in vitro and in vivo by Wang, Ying, Ou-Yang, Qiu-Geng, Huang, Wan-Li, Huang, Huan-le, Zhuang, Xin-Lei, Lin, Qian-Meng, Zeng, Da-Li

“…Lidocaine has cardiovascular and neurologic toxicity, which is dose-dependent. Due to CYP3A4-involved metabolism, lidocaine may be prone to drug-drug…”
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Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS by Zheng, Xiang, Wen, Jian, Liu, Teng-hui, Ou-yang, Qiu-Geng, Cai, Jian-ping, Zhou, Hong-yu

“…Objective. To discuss the effects of genistein on the metabolism of celecoxib in vitro and in vivo. Method. In vitro, the effects of genistein on the…”
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Inhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC-MS/MS by Wen, Jian, Bao, Su-Su, Zhang, Bo-Wen, Liu, Teng-Hui, Ou-Yang, Qiu-Geng, Cai, Jian-Ping, Zhou, Hong-Yu

“…Objective: To investigate the impact of resveratrol on the metabolism of ibrutinib in vitro and in vivo. Methods: In vitro, rat liver microsomes (RLM) and…”
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The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro by Xu, Ren-Ai, Gu, Er-Min, Liu, Teng-Hui, Ou-Yang, Qiu-Geng, Hu, Guo-Xin, Cai, Jian-Ping

“…CYP/CYP450 2C19 (CYP2C19) is a highly polymorphic enzyme and exhibits individual differences in metabolic activity. The purpose of this research was mainly to…”
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