Search Results - "Ou, Xianghong"
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SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation
Published in Aging cell (01-08-2018)“…SIRT4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes…”
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Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models
Published in Nature communications (28-11-2022)“…Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with systemic pathologies, including reproductive disorders in male…”
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3
Novel cardiac cell subpopulations: Pnmt-derived cardiomyocytes
Published in Open biology (01-08-2020)“…Diversity among highly specialized cells underlies the fundamental biology of complex multi-cellular organisms. One of the essential scientific questions in…”
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Roles of sphingosine-1-phosphate in reproduction
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-05-2014)“…Sphingosine-1-phosphate (S1P) plays crucial roles in the regulation of cell growth, proliferation, differentiation, cell survival, migration, and angiogenesis…”
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Effects of sphingosine-1-phosphate on gene expression of two cell mouse embryos induced by C2-Ceramide
Published in Middle East Fertility Society journal (01-06-2014)“…As to understand the sphingosine-1-phosphate (S1P) on gene expression of the pre-implantation mouse embryo induced by C2-Ceramide (CED). Global gene-expression…”
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6
Chromosomal microarray analysis of infertile men with azoospermia factor microdeletions
Published in Gene (20-04-2020)“…•We investigated Y-linked CNVs and variable phenotypes in infertile men.•The results of CMA and multiplex PCR analyses were generally concordant.•The…”
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Stage-specific H3K9me3 occupancy ensures retrotransposon silencing in human pre-implantation embryos
Published in Cell stem cell (07-07-2022)“…H3K9me3, as a hallmark of heterochromatin, is important for cell-fate specification. However, it remains unknown how H3K9me3 is reprogrammed during human early…”
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ARHGAP26 deficiency drives the oocyte aneuploidy and early embryonic development failure
Published in Cell death and differentiation (23-09-2024)“…Aneuploidy, the presence of a chromosomal anomaly, is a major cause of spontaneous abortions and recurrent pregnancy loss in humans. However, the underlying…”
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Rab24 functions in meiotic apparatus assembly and maturational progression in mouse oocyte
Published in Cell cycle (Georgetown, Tex.) (02-11-2019)“…Rab GTPases have multiple regulatory functions in intracellular vesicle transport. In recent years, there has been an increasing interest in the roles of Rab…”
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Novel mutations in TUBB8 expand the mutational and phenotypic spectrum of patients with zygotes containing multiple pronuclei
Published in Gene (15-02-2021)“…•We identified 3 novel heterozygous missense mutations in TUBB8.•All patients had experienced 2–3 failed IVF/ICSI attempts due to zygotic developmental…”
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The cohesion establishment factor Esco1 acetylates α-tubulin to ensure proper spindle assembly in oocyte meiosis
Published in Nucleic acids research (16-03-2018)“…Abstract Esco1 has been reported to function as a cohesion establishment factor that mediates chromosome cohesion and segregation in mitotic cells. However,…”
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12
IVF embryo choices and pregnancy outcomes
Published in Prenatal diagnosis (01-12-2021)“…Objective Investigate the chromosome status and transfer outcomes of embryos selected using routine “best morphology” IVF practices. Method A prospective…”
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13
Histone methyltransferase SETD2 is required for meiotic maturation in mouse oocyte
Published in Journal of cellular physiology (01-01-2019)“…SET‐domain‐containing 2 (SETD2), a member of the histone lysine methyltransferase family, has been reported to be involved in multiple biological processes…”
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14
PGT‐A: The biology and hidden failures of randomized control trials
Published in Prenatal diagnosis (01-08-2022)“…Objective Preimplantation Genetic Testing ‐ Aneuploidy (PGT‐A) for embryo selection has undergone significant advancements in the last 2 decades and yet many…”
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Relationship between macrophages in mouse uteri and angiogenesis in endometrium during the peri-implantation period
Published in Theriogenology (15-10-2014)“…The objective of this study is to examine the change in macrophage numbers, inducible form of NO synthase (iNOS), and vascular endothelial growth factor (VEGF)…”
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SIRT 4 is essential for metabolic control and meiotic structure during mouse oocyte maturation
Published in Aging cell (01-08-2018)“…SIRT 4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse…”
Get full text
Journal Article -
17
The outcome of different post-thawed culture period in frozen-thawed embryo transfer cycle
Published in Journal of assisted reproduction and genetics (01-12-2013)“…Purpose To study the influence of post-thawed culture (2–4 h and 20–24 h) on the outcome of frozen-thawed embryo transfer (FET) cycle. Methods In this…”
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Sphingosine-1-phosphate inhibits ceramide-induced apoptosis during murine preimplantation embryonic development
Published in Theriogenology (01-08-2013)“…Sphingolipids are a complex family of naturally occurring molecules enriched with lipid rafts that contribute to their unique biochemical properties…”
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19
Role of macrophages in mouse uterine during the peri-implantation period
Published in Nan fang yi ke da xue xue bao = Journal of Southern Medical University (01-03-2015)“…To investigate the effect of macrophages on embryo implantation by observing the distribution of macrophages in mouse uterine tissues during the…”
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Effect of basal serum luteinizing hormone and luteinizing hormone/follicle-stimulating hormone ratio on outcomes of in vitro fertilization-embryo transfer in patients with polycystic ovarian syndrome
Published in Nan fang yi ke da xue xue bao = Journal of Southern Medical University (01-06-2013)“…To evaluate the effect of basal serum luteinizing hormone (LH) and luteinizing hormone/follicle-stimulating hormone (LH/FSH) ratio on the clinical outcomes of…”
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