Search Results - "Ou, Xiang‐Hong"

Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans by Sha, Qian-Qian, Zheng, Wei, Wu, Yun-Wen, Li, Sen, Guo, Lei, Zhang, Shuoping, Lin, Ge, Ou, Xiang-Hong, Fan, Heng-Yu

“…Maternal mRNA clearance is an essential process that occurs during maternal-to-zygotic transition (MZT). However, the dynamics, functional importance, and…”
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Effects of obesity and diabetes on the epigenetic modification of mammalian gametes by Ou, Xiang‐Hong, Zhu, Cheng‐Cheng, Sun, Shao‐Chen

“…Obesity and diabetes are closely associated with numerous reproductive disorders, including termination of ovulation, irregular menstruation, low fertility,…”
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CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte by Sha, Qian‐Qian, Yu, Jia‐Li, Guo, Jing‐Xin, Dai, Xing‐Xing, Jiang, Jun‐Chao, Zhang, Yin‐Li, Yu, Chao, Ji, Shu‐Yan, Jiang, Yu, Zhang, Song‐Ying, Shen, Li, Ou, Xiang‐Hong, Fan, Heng‐Yu

“…Meiotic resumption‐coupled degradation of maternal transcripts occurs during oocyte maturation in the absence of mRNA transcription. The CCR4–NOT complex has…”
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CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes by Sha, Qian-Qian, Dai, Xing-Xing, Jiang, Jun-Chao, Yu, Chao, Jiang, Yu, Liu, Junping, Ou, Xiang-Hong, Zhang, Song-Ying, Fan, Heng-Yu

“…Trimethylation of histone H3 on lysine-4 (H3K4me3) is associated with gene-regulatory elements, but its transcription-independent function in cell division is…”
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Single‐cell RNA sequencing reveals the landscape of early female germ cell development by Zhao, Zheng‐Hui, Ma, Jun‐Yu, Meng, Tie‐Gang, Wang, Zhen‐Bo, Yue, Wei, Zhou, Qian, Li, Sen, Feng, Xie, Hou, Yi, Schatten, Heide, Ou, Xiang‐Hong, Sun, Qing‐Yuan

“…Meiosis initiation is a crucial step for the production of haploid gametes, which occurs from anterior to posterior in fetal ovaries. The asynchrony of the…”
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A combinatorial code for mRNA 3′-UTR-mediated translational control in the mouse oocyte by Dai, Xing-Xing, Jiang, Jun-Chao, Sha, Qian-Qian, Jiang, Yu, Ou, Xiang-Hong, Fan, Heng-Yu

“…Abstract Meiotic maturation of mammalian oocytes depends on the temporally and spatially regulated cytoplasmic polyadenylation and translational activation of…”
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PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome by Meng, Tie-Gang, Zhou, Qian, Ma, Xue-Shan, Liu, Xiao-Yu, Meng, Qing-Ren, Huang, Xian-Ju, Liu, Hong-Lin, Lei, Wen-Long, Zhao, Zheng-Hui, Ouyang, Ying-Chun, Hou, Yi, Schatten, Heide, Ou, Xiang-Hong, Wang, Zhen-Bo, Gao, Shao-Rong, Sun, Qing-Yuan

“…The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27…”
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CFP1-dependent histone H3K4 trimethylation in murine oocytes facilitates ovarian follicle recruitment and ovulation in a cell-nonautonomous manner by Sha, Qian-Qian, Jiang, Yu, Yu, Chao, Xiang, Yunlong, Dai, Xing-Xing, Jiang, Jun-Chao, Ou, Xiang-Hong, Fan, Heng-Yu

“…CxxC-finger protein 1 (CFP1)-mediated trimethylated histone H3 at lysine-4 (H3K4me3) during oocyte development enables the oocyte genome to establish the…”
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Single-cell RNA sequencing analysis of mouse follicular somatic cells by Li, Sen, Chen, Lei-Ning, Zhu, Hai-Jing, Feng, Xie, Xie, Feng-Yun, Luo, Shi-Ming, Ou, Xiang-Hong, Ma, Jun-Yu

“…Within the development of ovarian follicle, in addition to cell proliferation and differentiation, sophisticated cell–cell cross talks are established among…”
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Single‐cell transcriptome analysis reveals that maternal obesity affects DNA repair, histone methylation, and autophagy level in mouse embryos by Pan, Meng‐Hao, Zhu, Cheng‐Cheng, Ju, Jia‐Qian, Xu, Yi, Luo, Shi‐Ming, Sun, Shao‐Chen, Ou, Xiang‐Hong

“…Obesity causes many reproductive dysfunctions such as reduced conception, infertility, and early pregnancy loss, and this is largely due to the negative…”
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Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation by Meng, Tie-Gang, Lu, Xukun, Guo, Lei, Hou, Guan-Mei, Ma, Xue-Shan, Li, Qian-Nan, Huang, Lin, Fan, Li-Hua, Zhao, Zheng-Hui, Ou, Xiang-Hong, Yang, Ying-Chun Ou, Schatten, Heide, Li, Lei, Wang, Zhen-Bo, Sun, Qing-Yuan

“…ABSTRACT N6‐methyladenosine (m6A) is the most prevalent and reversible internal modification of mammalian messenger and noncoding RNAs mediated by specific m6A…”
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Effects of various calcium transporters on mitochondrial Ca2+ changes and oocyte maturation by Wang, Feng, Fan, Li‐Hua, Li, Ang, Dong, Feng, Hou, Yi, Schatten, Heide, Sun, Qing‐Yuan, Ou, Xiang‐Hong

“…Ca2+ participates in many important cellular processes, but the underlying mechanisms are still poorly understood, especially during oocyte maturation. First,…”
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Increase of mitochondria surrounding spindle causes mouse oocytes arrested at metaphase I stage by Wang, Xing-Hua, Yin, Shen, Ou, Xiang-Hong, Luo, Shi-Ming

“…During oocyte meiosis, mitochondria usually surround spindle to meet the energy demand of spindle migration and chromosome segregation. Therefore, the…”
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Cruciform DNA in mouse growing oocytes: Its dynamics and its relationship with DNA transcription by Feng, Xie, Xie, Feng-Yun, Ou, Xiang-Hong, Ma, Jun-Yu

“…Cruciform DNA is a causing factor of genome instability and chromosomal translocation, however, most studies about cruciform DNA in mammalian cells were based…”
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Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing by Zhang, Jue, Zhang, Yin-Li, Zhao, Long-Wen, Guo, Jing-Xin, Yu, Jia-Li, Ji, Shu-Yan, Cao, Lan-Rui, Zhang, Song-Ying, Shen, Li, Ou, Xiang-Hong, Fan, Heng-Yu

“…During mammalian oocyte growth, chromatin configuration transition from the nonsurrounded nucleolus (NSN) to surrounded nucleolus (SN) type plays a key role in…”
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Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis by Li, Sen, Chen, Lei-Ling, Wang, Xing-Hua, Zhu, Hai-Jing, Li, Xiao-Long, Feng, Xie, Guo, Lei, Ou, Xiang-Hong, Ma, Jun-Yu

“…Spontaneous abortion is an impeding factor for the success rates of human assistant reproductive technology (ART). Causes of spontaneous abortion include not…”
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FMNL2 regulates actin for endoplasmic reticulum and mitochondria distribution in oocyte meiosis by Pan, Meng-Hao, Zhang, Kun-Huan, Wu, Si-Le, Pan, Zhen-Nan, Sun, Ming-Hong, Li, Xiao-Han, Ju, Jia-Qian, Luo, Shi-Ming, Ou, Xiang-Hong, Sun, Shao-Chen

“…During mammalian oocyte meiosis, spindle migration and asymmetric cytokinesis are unique steps for the successful polar body extrusion. The asymmetry defects…”
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The N‐terminal His‐tag affects the triglyceride lipase activity of hormone‐sensitive lipase in testis by Wang, Feng, Ren, Xiao‐Fang, Chen, Zheng, Li, Xiao‐Long, Zhu, Hai‐Jing, Li, Sen, Ou, Xiang‐Hong, Zhang, Cheng, Zhang, Fei‐Xiong, Zhu, Bao‐Chang

“…The sterility of hormone‐sensitive lipase (HSL) knockout mice clearly shows the link between lipid metabolism and spermatogenesis. However, which substrate or…”
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Correction: Chromosomal variants accumulate in genomes of the spontaneous aborted fetuses revealed by chromosomal microarray analysis by Li, Sen, Chen, Lei-Ning, Wang, Xing-Hua, Zhu, Hai-Jing, Li, Xiao-Long, Feng, Xie, Guo, Lei, Ou, Xiang-Hong, Ma, Jun-Yu

“…[This corrects the article DOI: 10.1371/journal.pone.0259518.]…”
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Double-strand breaks induce short-scale DNA replication and damage amplification in the fully grown mouse oocytes by Ma, Jun-Yu, Feng, Xie, Xie, Feng-Yun, Li, Sen, Chen, Lei-Ning, Luo, Shi-Ming, Yin, Shen, Ou, Xiang-Hong

“…Abstract Break-induced replication (BIR) is essential for the repair of DNA double-strand breaks (DSBs) with single ends. DSBs-induced microhomology-mediated…”
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