Search Results - "Ou, Jianhong"

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    Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis by Kobayashi, Yoshihiko, Tata, Aleksandra, Konkimalla, Arvind, Katsura, Hiroaki, Lee, Rebecca F., Ou, Jianhong, Banovich, Nicholas E., Kropski, Jonathan A., Tata, Purushothama Rao

    Published in Nature cell biology (01-08-2020)
    “…Stem cells undergo dynamic changes in response to injury to regenerate lost cells. However, the identity of transitional states and the mechanisms that drive…”
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    Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding by Kadota, Shinichi, Ou, Jianhong, Shi, Yuming, Lee, Jeannie T., Sun, Jiayu, Yildirim, Eda

    Published in Nature communications (25-05-2020)
    “…Nucleoporin proteins (Nups) have been proposed to mediate spatial and temporal chromatin organization during gene regulation. Nevertheless, the molecular…”
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    Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis by Yang, Tianqi, Ou, Jianhong, Yildirim, Eda

    Published in Nature communications (01-08-2022)
    “…X chromosome inactivation (XCI) is a dosage compensation phenomenon that occurs in females. Initiation of XCI depends on Xist RNA, which triggers silencing of…”
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    The BRAF Oncoprotein Functions through the Transcriptional Repressor MAFG to Mediate the CpG Island Methylator Phenotype by Fang, Minggang, Ou, Jianhong, Hutchinson, Lloyd, Green, Michael R.

    Published in Molecular cell (18-09-2014)
    “…Most colorectal cancers (CRCs) containing activated BRAF (BRAF[V600E]) have a CpG island methylator phenotype (CIMP) characterized by aberrant hypermethylation…”
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    ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data by Ou, Jianhong, Liu, Haibo, Yu, Jun, Kelliher, Michelle A, Castilla, Lucio H, Lawson, Nathan D, Zhu, Lihua Julie

    Published in BMC genomics (01-03-2018)
    “…ATAC-seq (Assays for Transposase-Accessible Chromatin using sequencing) is a recently developed technique for genome-wide analysis of chromatin accessibility…”
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    Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model by Hoye, Mariah L, Calviello, Lorenzo, Poff, Abigail J, Ejimogu, Nna-Emeka, Newman, Carly R, Montgomery, Maya D, Ou, Jianhong, Floor, Stephen N, Silver, Debra L

    Published in eLife (28-06-2022)
    “…Mutations in the RNA helicase, , are a leading cause of Intellectual Disability and present as syndrome, a neurodevelopmental disorder associated with cortical…”
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    RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis by Wang, Mu-En, Chen, Jiaqi, Lu, Yi, Bawcom, Alyssa R, Wu, Jinjin, Ou, Jianhong, Asara, John M, Armstrong, Andrew J, Wang, Qianben, Li, Lei, Wang, Yuzhuo, Huang, Jiaoti, Chen, Ming

    Published in The Journal of clinical investigation (15-05-2023)
    “…Inactivation of the RB1 tumor suppressor gene is common in several types of therapy-resistant cancers, including metastatic castration-resistant prostate…”
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    TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein by Bhatnagar, Sanchita, Gazin, Claude, Chamberlain, Lynn, Ou, Jianhong, Zhu, Xiaochun, Tushir, Jogender S., Virbasius, Ching-Man, Lin, Ling, Zhu, Lihua J., Wajapeyee, Narendra, Green, Michael R.

    Published in Nature (London) (04-12-2014)
    “…The RING finger protein TRIM37 is encoded by a gene that is amplified in certain breast cancers, but its function is unknown; here, it is shown to…”
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    Electrosynthesis of Organic Compounds from Carbon Dioxide Is Catalyzed by a Diversity of Acetogenic Microorganisms by Nevin, Kelly P, Hensley, Sarah A, Franks, Ashley E, Summers, Zarath M, Ou, Jianhong, Woodard, Trevor L, Snoeyenbos-West, Oona L, Lovley, Derek R

    Published in Applied and Environmental Microbiology (01-05-2011)
    “…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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    Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity by Pan, Dongning, Huang, Lei, Zhu, Lihua J., Zou, Tie, Ou, Jianhong, Zhou, William, Wang, Yong-Xu

    Published in Developmental cell (07-12-2015)
    “…Progression from brown preadipocytes to adipocytes engages two transcriptional programs: the expression of adipogenic genes common to both brown fat (BAT) and…”
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    Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish by Han, Yanchao, Chen, Anzhi, Umansky, Kfir-Baruch, Oonk, Kelsey A., Choi, Wen-Yee, Dickson, Amy L., Ou, Jianhong, Cigliola, Valentina, Yifa, Oren, Cao, Jingli, Tornini, Valerie A., Cox, Ben D., Tzahor, Eldad, Poss, Kenneth D.

    Published in Developmental cell (25-03-2019)
    “…Attaining proper organ size during development and regeneration hinges on the activity of mitogenic factors. Here, we performed a large-scale chemical screen…”
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    VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin by Elaimy, Ameer L, Guru, Santosh, Chang, Cheng, Ou, Jianhong, Amante, John J, Zhu, Lihua Julie, Goel, Hira Lal, Mercurio, Arthur M

    Published in Science signaling (01-05-2018)
    “…The role of vascular endothelial growth factor (VEGF) signaling in cancer is not only well known in the context of angiogenesis but also important in the…”
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    Enhancer selection dictates gene expression responses in remote organs during tissue regeneration by Sun, Fei, Ou, Jianhong, Shoffner, Adam R., Luan, Yu, Yang, Hongbo, Song, Lingyun, Safi, Alexias, Cao, Jingli, Yue, Feng, Crawford, Gregory E., Poss, Kenneth D.

    Published in Nature cell biology (01-05-2022)
    “…Acute trauma stimulates local repair mechanisms but can also impact structures distant from the injury, for example through the activity of circulating…”
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    U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3′ End Formation by Park, Sung Mi, Ou, Jianhong, Chamberlain, Lynn, Simone, Tessa M., Yang, Huan, Virbasius, Ching-Man, Ali, Abdullah M., Zhu, Lihua Julie, Mukherjee, Siddhartha, Raza, Azra, Green, Michael R.

    Published in Molecular cell (19-05-2016)
    “…Recurrent mutations in the splicing factor U2AF35 are found in several cancers and myelodysplastic syndrome (MDS). How oncogenic U2AF35 mutants promote…”
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    Tead and AP1 Coordinate Transcription and Motility by Liu, Xiangfan, Li, Huapeng, Rajurkar, Mihir, Li, Qi, Cotton, Jennifer L., Ou, Jianhong, Zhu, Lihua J., Goel, Hira L., Mercurio, Arthur M., Park, Joo-Seop, Davis, Roger J., Mao, Junhao

    Published in Cell reports (Cambridge) (09-02-2016)
    “…The Tead family transcription factors are the major intracellular mediators of the Hippo-Yap pathway. Despite the importance of Hippo signaling in…”
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    Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation by Huang, Lei, Pan, Dongning, Chen, Qingbo, Zhu, Lihua J., Ou, Jianhong, Wabitsch, Martin, Wang, Yong-Xu

    Published in Nature communications (12-07-2017)
    “…Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that…”
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    miR-146a promotes the initiation and progression of melanoma by activating Notch signaling by Forloni, Matteo, Dogra, Shaillay Kumar, Dong, Yuying, Conte, Jr, Darryl, Ou, Jianhong, Zhu, Lihua Julie, Deng, April, Mahalingam, Meera, Green, Michael R, Wajapeyee, Narendra

    Published in eLife (18-02-2014)
    “…Oncogenic mutations in BRAF and NRAS occur in 70% of melanomas. In this study, we identify a microRNA, miR-146a, that is highly upregulated by oncogenic BRAF…”
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    MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway by Janostiak, Radoslav, Rauniyar, Navin, Lam, TuKiet T., Ou, Jianhong, Zhu, Lihua J., Green, Michael R., Wajapeyee, Narendra

    Published in Cell reports (Cambridge) (05-12-2017)
    “…Melanoma accounts for more than 80% of skin cancer-related deaths, and current therapies provide only short-term benefit to patients. Here, we show in melanoma…”
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