Search Results - "Oturai, A B"

The neutrophil-to-lymphocyte ratio is associated with multiple sclerosis by Hasselbalch, IC, Søndergaard, HB, Koch-Henriksen, N, Olsson, A, Ullum, H, Sellebjerg, F, Oturai, AB

“…Background Subtypes of white blood cell counts are known biomarkers of systemic inflammation and a high neutrophil-to-lymphocyte ratio (NLR) has been…”
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Short-term, high-dose glucocorticoid treatment does not contribute to reduced bone mineral density in patients with multiple sclerosis by Olsson, A, Oturai, DB, Sørensen, PS, Oturai, PS, Oturai, AB

“…Background: Patients with multiple sclerosis (MS) are at increased risk of reduced bone mineral density (BMD). A contributing factor might be treatment with…”
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Early safety and efficacy of fingolimod treatment in Denmark by Voldsgaard, A., Koch‐Henriksen, N., Magyari, M., Sellebjerg, F., Sørensen, P. S., Oturai, A. B.

“…Background Initiation of fingolimod treatment is associated with a transient decrease of heart rate, and atrioventricular (AV) conduction block may occur…”
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Efficacy of natalizumab in multiple sclerosis patients with high disease activity: a Danish nationwide study by Oturai, A. B., Koch-Henriksen, N., Petersen, T., Jensen, P. E. H., Sellebjerg, F., Sorensen, P. S.

“…Introduction:  Previous studies of natalizumab (Tysabri®) in relapsing multiple sclerosis (MS) patients have included patients with moderate disease activity…”
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RGMA and IL21R show association with experimental inflammation and multiple sclerosis by Nohra, R, Beyeen, A D, Guo, J P, Khademi, M, Sundqvist, E, Hedreul, M T, Sellebjerg, F, Smestad, C, Oturai, A B, Harbo, H F, Wallström, E, Hillert, J, Alfredsson, L, Kockum, I, Jagodic, M, Lorentzen, J, Olsson, T

“…Rat chromosome 1 harbors overlapping quantitative trait loci (QTL) for cytokine production and experimental models of inflammatory diseases. We fine-dissected…”
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Soluble serum VCAM-1, whole blood mRNA expression and treatment response in natalizumab-treated multiple sclerosis by Petersen, ER, Søndergaard, HB, Oturai, AB, Jensen, PEH, Sorensen, PS, Sellebjerg, F, Börnsen, L

“…Abstract Background Natalizumab reduces disease activity in multiple sclerosis (MS). Natalizumab binds to the very late antigen-4 and inhibits vascular cell…”
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Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRB11501, CCR5 deletion mutation, apolipoprotein E) by Schreiber, K, Oturai, A B, Ryder, L P, Madsen, H O, Jørgensen, O S, Svejgaard, A, Sorensen, P S

“…As the understanding of the autoimmune inflammatory response in multiple sclerosis (MS) expands, polymorphic genes involved in this process become possible…”
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Expression of melanoma cell adhesion molecule-1 (MCAM-1) in natalizumab-treated multiple sclerosis by Petersen, E.R., Ammitzbøll, C., Søndergaard, H.B., Oturai, A.B., Sørensen, P.S., Nilsson, A.C., Börnsen, L., von Essen, M., Sellebjerg, F.

“…The objectives were to study the expression of very late antigen (VLA)-4, melanoma cell adhesion molecule-1 (MCAM-1) and activated leukocyte cell adhesion…”
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Circulating levels of tight junction proteins in multiple sclerosis: Association with inflammation and disease activity before and after disease modifying therapy by Olsson, A., Gustavsen, S., Langkilde, A.R., Hansen, T.H., Sellebjerg, F., Bach Søndergaard, H., Oturai, A.B.

“…•Tight junction proteins contribute to maintenance of epithelial and endothelial barriers.•Circulating occludin levels are higher in newly diagnosed, untreated…”
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Neurosurgery for Trigeminal Neuralgia: Comparison of Alcohol Block, Neurectomy, and Radiofrequency Coagulation by Oturai, A B, Jensen, K, Eriksen, J, Madsen, F

“…OBJECTIVES:We wished to assess the present condition of patients previously treated with a neurosurgical procedure or procedures for trigeminal neuralgia (TN)…”
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Bone microarchitecture and bone mineral density in multiple sclerosis by Olsson, A., Oturai, A. B., Søndergaard, H. B., Sellebjerg, F., Oturai, P. S.

“…Background Multiple sclerosis (MS) patients are at increased risk of reduced bone mineral density (BMD) and fractures. The aetiology of bone loss in MS is…”
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Biomarkers of inflammation and epithelial barrier function in multiple sclerosis by Olsson, A., Gustavsen, S., Hasselbalch, I. Chenoufi, Langkilde, A.R., Sellebjerg, F., Oturai, A.B., Søndergaard, H. Bach

“…•Serum calprotectin and NfL levels are higher in MS patients compared with healthy controls•Serum calprotectin levels are associated with disease activity in…”
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Illegal cannabis use is common among Danes with multiple sclerosis by Gustavsen, S., Søndergaard, H.B., Andresen, S.R., Magyari, M., Sørensen, P.S., Sellebjerg, F., Oturai, A.B.

“…•Illegal cannabis use is common among Danes with multiple sclerosis.•Cannabis was used within the past year (current user) by 21%.•21% of current users…”
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Prediction of response to interferon therapy in multiple sclerosis by Sellebjerg, F., Søndergaard, H. B., Koch-Henriksen, N., Sørensen, P. S., Oturai, A. B.

“…Objective Single nucleotide polymorphisms (SNPs) in the genes encoding interferon response factor (IRF)‐5, IRF‐8 and glypican‐5 (GPC5) have been associated…”
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Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes by Enevold, C., Kjær, L., Nielsen, C. H., Voss, A., Jacobsen, R. S., Hermansen, M. L. F., Redder, L., Oturai, A. B., Jensen, P. E., Bendtzen, K., Jacobsen, S.

“…This study aimed to demonstrate possible associations between genetic polymorphisms in Toll-like receptor 3, interferon induced with helicase C domain 1…”
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The chemokine receptor CCR5 Δ32 allele in natalizumab-treated multiple sclerosis by Møller, M., Søndergaard, H. B., Koch-Henriksen, N., Sorensen, P. S., Sellebjerg, F., Oturai, A. B.

“…Objective The chemokine receptor CCR5 may be important for the recruitment of pathogenic T cells to the CNS in multiple sclerosis (MS). We hypothesized that…”
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Shift Work At Young Age is Associated with Increased Risk of Multiple Sclerosis In A Danish Population by Gustavsen, S, Søndergaard, H.B, Oturai, D.B, Laursen, B, Laursen, J.H, Magyari, M, Ullum, H, Larsen, M.H, Sellebjerg, F, Oturai, A.B

“…Abstract Background Epidemiological studies suggest an important role for environmental factors in developing multiple sclerosis (MS). Furthermore several…”
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Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort by Westerlind, Helga, Imrell, Kerstin, Ramanujam, Ryan, Myhr, Kjell-Morten, Celius, Elisabeth Gulowsen, Harbo, Hanne F, Oturai, Annette Bang, Hamsten, Anders, Alfredsson, Lars, Olsson, Tomas, Kockum, Ingrid, Koski, Timo, Hillert, Jan

“…In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared…”
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The chemokine receptor CCR5 Delta 32 allele in natalizumab-treated multiple sclerosis by Moeller, M, Soendergaard, H B, Koch-Henriksen, N, Sorensen, P S, Sellebjerg, F, Oturai, AB

“…The chemokine receptor CCR5 may be important for the recruitment of pathogenic T cells to the CNS in multiple sclerosis (MS). We hypothesized that this…”
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Concordance for disease course and age of onset in Scandinavian multiple sclerosis coaffected sib pairs by Oturai, Annette Bang, Ryder, Lars P, Fredrikson, Sten, Myhr, Kjell-Morten, Celius, Elisabeth G, Harbo, Hanne Flinstad, Andersen, Oluf, ASkesson, Eva, Hillert, Jan, Madsen, Hans O, Nyland, Harald, Spurkland, Anne, Datta, Pameli, Svejgaard, Arne, Sorensen, Per S

“…Background: Investigation of coaffected sib pairs is one method to determine the genetic influence on the clinical presentatio n of many complex diseases, such…”
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