Search Results - "Otto‐Ślusarczyk, Dagmara"

BM7, a derivative of benzofuran, effectively fights cancer by promoting cancer cell apoptosis and impacting IL-6 levels by Napiórkowska, Mariola, Otto - Ślusarczyk, Dagmara, Kurpios-Piec, Dagmara, Stukan, Iga, Gryzik, Marek, Wojda, Urszula

“…The BM7 compound, a bromo derivative of methyl 6-acetyl-5-hydroxy-2-methyl-1-benzofuran-3-carboxylate, was previously identified as cytotoxic to human…”
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Novel Tetracyclic Azaphenothiazines with the Quinoline Ring as New Anticancer and Antibacterial Derivatives of Chlorpromazine by Jeleń, Małgorzata, Otto-Ślusarczyk, Dagmara, Morak-Młodawska, Beata, Struga, Marta

“…Phenothiazine derivatives are widely studied in various fields such as biology, chemistry, and medicine research because of their pharmaceutical effects. The…”
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Design and Synthesis of Menthol and Thymol Derived Ciprofloxacin: Influence of Structural Modifications on the Antibacterial Activity and Anticancer Properties by Szostek, Tomasz, Szulczyk, Daniel, Szymańska-Majchrzak, Jolanta, Koliński, Michał, Kmiecik, Sebastian, Otto-Ślusarczyk, Dagmara, Zawodnik, Aleksandra, Rajkowska, Eliza, Chaniewicz, Kinga, Struga, Marta, Roszkowski, Piotr

“…Sixteen new Ciprofloxacin derivatives were designed and successfully synthesized. In an in silico experiment, lipophilicity was established for obtained…”
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Clinical Phenotypes of Progressive Supranuclear Palsy—The Differences in Interleukin Patterns by Madetko-Alster, Natalia, Otto-Ślusarczyk, Dagmara, Wiercińska-Drapało, Alicja, Koziorowski, Dariusz, Szlufik, Stanisław, Samborska-Ćwik, Joanna, Struga, Marta, Friedman, Andrzej, Alster, Piotr

“…Progressive supranuclear palsy (PSP) is an atypical parkinsonian syndrome based on tau pathology; its clinical phenotype differs, but PSP with Richardson’s…”
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The potential significance of hepcidin evaluation in progressive supranuclear palsy by Alster, Piotr, Otto‐Ślusarczyk, Dagmara, Wiercińska‐Drapało, Alicja, Struga, Marta, Madetko‐Alster, Natalia

“…Introduction Hepcidin is a peptide associated with controlling the distribution of iron in tissues. Growing interest is linked with its impact on…”
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The significance of glial cell line-derived neurotrophic factor analysis in Progressive Supranuclear Palsy by Alster, Piotr, Otto-Ślusarczyk, Dagmara, Szlufik, Stanisław, Duszyńska-Wąs, Karolina, Drzewińska, Agnieszka, Wiercińska-Drapało, Alicja, Struga, Marta, Kutyłowski, Michał, Friedman, Andrzej, Madetko-Alster, Natalia

“…Progressive Supranuclear Palsy (PSP) is an atypical parkinsonism. Major subtypes of the disease: PSP-Richardson’s Syndrome (PSP-RS) and PSP Parkinsonism…”
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The associations between common neuroimaging parameters of Progressive Supranuclear Palsy in magnetic resonance imaging and non-specific inflammatory factors - pilot study by Alster, Piotr, Otto-Ślusarczyk, Dagmara, Kutyłowski, Michał, Migda, Bartosz, Wiercińska-Drapało, Alicja, Jabłońska, Joanna, Struga, Marta, Madetko-Alster, Natalia

“…Progressive Supranuclear Palsy is an atypical parkinsonism based on tauopathic pathology. Growing interest is associated with the pathomechanism of this…”
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The Real Cytotoxic Effect of Artemisinins on Colon Cancer Cells in a Physiological Cell Culture Setting. How Composition of the Culture Medium Biases Experimental Findings by Otto-Ślusarczyk, Dagmara, Mielczarek-Puta, Magdalena, Graboń, Wojciech

“…Artemisinin (ART) and dihydroartemisinin (DHA) are anti-malaria drugs but also exhibit huge anticancer potential based on ferroptosis driven by iron-dependent…”
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Exploring the bioactive potential of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives: A comprehensive review by Szostek, Tomasz, Otto-Ślusarczyk, Dagmara, Roszkowski, Piotr, Struga, Marta, Szulczyk, Daniel

“…[Display omitted] Thiazolidinone is a scaffold known for its diverse biological activities, drawing the interest of researchers seeking to explore its…”
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Synthesis of Lasalocid-Based Bioconjugates and Evaluation of Their Anticancer Activity by Antoszczak, Michał, Otto-Ślusarczyk, Dagmara, Kordylas, Marta, Struga, Marta, Huczyński, Adam

“…Using rationally designed bioconjugates is an attractive strategy to develop novel anticancer drugs with enhanced therapeutic potential and minimal side…”
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Ivermectin and its synthetic derivatives – A new class of anticancer agents by Sulik, Michał, Otto-Ślusarczyk, Dagmara, Antoszczak, Michał, Struga, Marta, Huczyński, Adam

“…Ivermectin (IVR) is a 16-membered macrocyclic lactone of Nobel prize-honored distinction, showing a broad spectrum of biological activity, especially…”
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N‑Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents by Struga, Marta, Roszkowski, Piotr, Bielenica, Anna, Otto-Ślusarczyk, Dagmara, Stępień, Karolina, Stefańska, Joanna, Zabost, Anna, Augustynowicz-Kopeć, Ewa, Koliński, Michał, Kmiecik, Sebastian, Myslovska, Alina, Wrzosek, Małgorzata

“…A novel series of N-acylated ciprofloxacin (CP) conjugates 1–21 were synthesized and screened as potential antimicrobial agents. Conjugates 1 and 2 were…”
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Teriflunomide – The common drug with underestimated oxygen - Dependent anticancer potential by Otto-Ślusarczyk, Dagmara, Graboń, Wojciech, Mielczarek-Puta, Magdalena, Chrzanowska, Alicja

“…Leflunomide (LFN) is a well-known immunomodulatory and anti-inflammatory prodrug of teriflunomide (TFN). Due to pyrimidine synthesis inhibition TFN also…”
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Lactate Formation in Primary and Metastatic Colon Cancer Cells at Hypoxia and Normoxia by Graboń, Wojciech, Otto-Ślusarczyk, Dagmara, Chrzanowska, Alicja, Mielczarek-Puta, Magdalena, Joniec-Maciejak, Ilona, Słabik, Krzysztof, Barańczyk-Kuźma, Anna

“…High glucose consumption and lactate synthesis in aerobic glycolysis are a hallmark of cancer cells. They can form lactate also in glutaminolysis, but it is…”
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Telmisartan Influences the Antiproliferative Activity of Linoleic Acid in Human Colon Cancer Cells by Mielczarek-Puta, Magdalena, Otto-Ślusarczyk, Dagmara, Chrzanowska, Alicja, Filipek, Agnieszka, Graboń, Wojciech

“…Aim: Linoleic acid (LA) and telmisartan as PPARgamma agonists exhibit anticancer activity. The LA effect is observed for high non-achievable in vivo…”
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Aspartate aminotransferase--key enzyme in the human systemic metabolism by Otto-Ślusarczyk, Dagmara, Graboń, Wojciech, Mielczarek-Puta, Magdalena

“…Aspartate aminotransferase is an organ-nonspecific enzyme located in many tissues of the human body where it catalyzes reversible reaction of transamination…”
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Asymmetric synthesis and in vivo/in vitro characterization of new hybrid anticonvulsants derived from (2,5-dioxopyrrolidin-1-yl)phenylacetamides by Abram, Michał, Rapacz, Anna, Latacz, Gniewomir, Szulczyk, Bartłomiej, Kalinowska-Tłuścik, Justyna, Otto-Ślusarczyk, Dagmara, Struga, Marta, Kamiński, Rafał M., Kamiński, Krzysztof

“…[Display omitted] •New hybrid anticonvulsants were obtained applying the multistep asymmetric procedure.•X-ray crystallography was used to solve the spatial…”
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Influence of oxygen availability on expression of glutaminolysis genes in human colon cancer cells by Otto-Ślusarczyk, Dagmara, Graboń, Wojciech, Mielczarek-Puta, Magdalena, Chrzanowska, Alicja, Barańczyk-Kuźma, Anna

“…Abstract Introduction Glutaminolysis, beside glycolysis, is a key metabolic pathway of a cancer cell that provides energy and substrates for the synthesis of…”
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Glucose Metabolism and Cognitive Decline in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Preliminary Study by Madetko-Alster, Natalia, Otto-Ślusarczyk, Dagmara, Struga, Marta, Kutyłowski, Michał, Drzewińska, Agnieszka, Duszyńska-Wąs, Karolina, Migda, Bartosz, Alster, Piotr

“…Multiple studies have analyzed the possible correlations between diabetes and Alzheimer's disease. Less is known about the context of cognitive deterioration…”
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Influence of oxygen on the Warburg effect: do cancer cells produce lactate only from glucose? by Graboń, Wojciech, Otto-Ślusarczyk, Dagmara, Barańczyk-Kuźma, Anna

“…The common characteristics of many tumors is phenomenon termed the Warburg effect – the production of abundant amounts of lactate in the presence of sufficient…”
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