Search Results - "Otto, Frank"

Improvement of the antimicrobial potency, pharmacokinetic and pharmacodynamic properties of albicidin by incorporation of nitrogen atoms by Zborovsky, Lieby, Kleebauer, Leonardo, Seidel, Maria, Kostenko, Arseni, von Eckardstein, Leonard, Gombert, Frank Otto, Weston, John, Süssmuth, Roderich D

“…The worrisome development and spread of multidrug-resistant bacteria demands new antibacterial agents with strong bioactivities particularly against…”
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Extraction of active ingredients from green tea ( Camellia sinensis): Extraction efficiency of major catechins and caffeine by Perva-Uzunalić, Amra, Škerget, Mojca, Knez, Željko, Weinreich, Bernd, Otto, Frank, Grüner, Sabine

“…The effect of different extraction set-ups that influence the extraction efficiency of catechins and caffeine from green tea leaves (variety Fanning Belas,…”
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A new occurrence of archosaur footprints from the Löwenstein Formation (Late Triassic, Middle Norian) of southern Germany by Wagensommer, Alexander, Porchetti, Simone D'Orazi, Bolter, Hans Dieter, Antonelli, Matteo, Haderer, Frank-Otto

“…Two sandstone slabs from a new Norian tetrapod tracksite in the Löwenstein Formation of southern Germany preserve a set of tracks including both tridactyl and…”
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S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration by Patente, Thiago A, Gasan, Thomas A, Scheenstra, Maaike, Ozir-Fazalalikhan, Arifa, Obieglo, Katja, Schetters, Sjoerd, Verwaerde, Stijn, Vergote, Karl, Otto, Frank, Wilbers, Ruud H P, van Bloois, Eline, Wijck, Yolanda van, Taube, Christian, Hammad, Hamida, Schots, Arjen, Everts, Bart, Yazdanbakhsh, Maria, Guigas, Bruno, Hokke, Cornelis H, Smits, Hermelijn H

“…Chronic infection with Schistosoma mansoni parasites is associated with reduced allergic sensitization in humans, while schistosome eggs protects against…”
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ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis by Vig, Saurabh, Lambooij, Joost M., Dekkers, Mette C., Otto, Frank, Carlotti, Françoise, Guigas, Bruno, Zaldumbide, Arnaud

“…Beta-cell destruction in type 1 diabetes (T1D) results from the combined effect of inflammation and recurrent autoimmunity. Accumulating evidence suggests the…”
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mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming by Pelgrom, Leonard R., Patente, Thiago A., Otto, Frank, Nouwen, Lonneke V., Ozir-Fazalalikhan, Arifa, van der Ham, Alwin J., van der Zande, Hendrik J.P., Heieis, Graham A., Arens, Ramon, Everts, Bart

“…How mechanistic target of rapamycin complex 1 (mTORC1), a key regulator of cellular metabolism, affects dendritic cell (DC) metabolism and T cell-priming…”
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High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2 by Almeida, Luís, van Roey, Ruthger, Patente, Thiago Andrade, Otto, Frank, Veldhuizen, Tom, Ghorasaini, Mohan, van Diepen, Angela, Schramm, Gabriele, Liu, Jianyang, Idborg, Helena, Korotkova, Marina, Jakobsson, Per-Johan, Giera, Martin, Hokke, Cornelis Hendrik, Everts, Bart

“…The parasitic helminth is a potent inducer of type 2 immune responses by stimulating dendritic cells (DCs) to prime T helper 2 (Th2) responses. We previously…”
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Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes by Verberk, Sanne G S, van der Zande, Hendrik J P, Baardman, Jeroen, de Goede, Kyra E, Harber, Karl J, Keuning, Eelco D, Lambooij, Joost M, Otto, Frank, Zawistowska-Deniziak, Anna, de Vries, Helga E, de Winther, Menno P J, Guigas, Bruno, Van den Bossche, Jan

“…Macrophages are highly plastic, key regulators of inflammation. Deregulation of macrophage activation can lead to excessive inflammation as seen in…”
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Dendritic cell-intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity by van der Zande, Hendrik Jp, Brombacher, Eline C, Lambooij, Joost M, Pelgrom, Leonard R, Zawistowska-Deniziak, Anna, Patente, Thiago A, Heieis, Graham A, Otto, Frank, Ozir-Fazalalikhan, Arifa, Yazdanbakhsh, Maria, Everts, Bart, Guigas, Bruno

“…Obesity-associated metabolic inflammation drives the development of insulin resistance and type 2 diabetes, notably through modulating innate and adaptive…”
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environmental issues from coal mining and their solutions by BIAN, Zhengfu, INYANG, Hilary I, DANIELS, John L, OTTO, Frank, STRUTHERS, Sue

“…The environmental challenges from coal mining include coal mine accidents, land subsidence, damage to the water environment, mining waste disposal and air…”
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Self-similar fragmentation regulated by magnetic fields in a region forming massive stars by Li, Hua-bai, Yuen, Ka Ho, Otto, Frank, Leung, Po Kin, Sridharan, T. K., Zhang, Qizhou, Liu, Hauyu, Tang, Ya-Wen, Qiu, Keping

“…Most molecular clouds are filamentary or elongated 1 , 2 , 3 . For those forming low-mass stars (<8 solar masses), the competition between self-gravity and…”
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Bringing Technology to English Language Learning: Making It Work by Frank Otto

“…Interactive Multimedia (IMM) has been accepted as an exemplary application of modern technology that is used to teach and learn foreign languages more…”
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Velocity Anisotropy in Self-gravitating Molecular Clouds. I. Simulation by Otto, Frank, Ji, Weiguang, Li, Hua-bai

“…The complex interplay between turbulence, magnetic fields, and self-gravity leads to the formation of molecular clouds out of the diffuse interstellar medium…”
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Accuracy of Potfit-based potential representations and its impact on the performance of (ML-)MCTDH by Otto, Frank, Chiang, Ying-Chih, Peláez, Daniel

“…[Display omitted] •Several Potfit-based methods are used to fit the potential energy surface of H3O2−.•These fits are used to compute its ground state via…”
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On the force field optimisation of Formula: see text-lactam cores using the force field Toolkit by Wu, Qiyang, Huang, Tianyang, Xia, Songyan, Otto, Frank, Lee, Tzong-Yi, Huang, Hsien-Da, Chiang, Ying-Chih

“…When employing molecular dynamics (MD) simulations for computer-aided drug design, the quality of the used force fields is highly important. Here we present…”
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On the force field optimisation of \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\beta$$\end{document}β-lactam cores using the force field Toolkit by Wu, Qiyang, Huang, Tianyang, Xia, Songyan, Otto, Frank, Lee, Tzong-Yi, Huang, Hsien-Da, Chiang, Ying-Chih

“…When employing molecular dynamics (MD) simulations for computer-aided drug design, the quality of the used force fields is highly important. Here we present…”
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On the force field optimisation of β-lactam cores using the force field Toolkit by Wu, Qiyang, Huang, Tianyang, Xia, Songyan, Otto, Frank, Lee, Tzong-Yi, Huang, Hsien-Da, Chiang, Ying-Chih

“…When employing molecular dynamics (MD) simulations for computer-aided drug design, the quality of the used force fields is highly important. Here we present…”
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Fuel consumption potential of gasoline engines in an electrified powertrain: homogeneous and heterogeneous lean combustion in comparison by Rurik, Alexander, Otto, Frank, Koch, Thomas

“…This paper evaluates the fuel consumption of homogeneous and heterogeneous lean combustion in the WLTC test cycle. A lean combustion engine is combined with an…”
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Strategy and potential of homogeneous lean combustion at high load points for turbocharged gasoline engines with direct injection and small displacement by Rurik, Alexander, Otto, Frank, Koch, Thomas

“…In this paper, a homogeneous lean combustion concept for gasoline engines with direct injection, small displacement and turbocharging is investigated under…”
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The helminth glycoprotein omega‐1 improves metabolic homeostasis in obese mice through type 2 immunity‐independent inhibition of food intake by Zande, Hendrik J.P., Gonzalez, Michael A., Ruiter, Karin, Wilbers, Ruud H.P., García‐Tardón, Noemí, Huizen, Mariska, Noort, Kim, Pelgrom, Leonard R., Lambooij, Joost M., Zawistowska‐Deniziak, Anna, Otto, Frank, Ozir‐Fazalalikhan, Arifa, Willigen, Danny, Welling, Mick, Poles, Jordan, Leeuwen, Fijs, Hokke, Cornelis H., Schots, Arjen, Yazdanbakhsh, Maria, Loke, P'ng, Guigas, Bruno

“…Type 2 immunity plays an essential role in the maintenance of metabolic homeostasis and its disruption during obesity promotes meta‐inflammation and insulin…”
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