Search Results - "Ottmüller, Katja J"
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Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset
Published in Blood (19-04-2018)“…Conditioning-induced damage of the intestinal tract plays a critical role during the onset of acute graft-versus-host disease (GVHD). Therapeutic interference…”
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Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
Published in Science immunology (12-01-2018)“…The thymus is not only extremely sensitive to damage but also has a remarkable ability to repair itself. However, the mechanisms underlying this endogenous…”
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Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion
Published in The Journal of experimental medicine (22-08-2016)“…Donor CD4(+)Foxp3(+) regulatory T cells (T reg cells) suppress graft-versus-host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HCT…”
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Non-Hematopoietic Lymphoid Stromal Cells Prime Alloreactive CD4+ T Cells in Acute Graft-Versus-Host Disease
Published in Blood (13-11-2019)“…Allogeneic T cell priming is considered as an essential event determining the outcome of allogeneic hematopoietic stem cell transplantation (allo-HCT), ideally…”
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Mechanisms Governing Endogenous Thymic Regeneration
Published in Blood (08-12-2017)“…Endogenous thymic regeneration is a crucial function that allows for renewal of immune competence following immunodepletion caused by common cancer therapies…”
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Tissue Derived Non-Classical Monocyte Derived Host Macrophages Protect Against Murine Intestinal Acute Graft-Versus-Host Disease
Published in Blood (29-11-2018)“…Acute graft versus host disease (aGVHD) remains a major complication in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), the…”
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