Search Results - "Ottestad, William"
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Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19?
Published in Molecular medicine (Cambridge, Mass.) (07-05-2020)“…The 2019 novel coronavirus disease (COVID-19) causes for unresolved reasons acute respiratory distress syndrome in vulnerable individuals. There is a need to…”
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Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
Published in Molecular medicine (Cambridge, Mass.) (26-03-2021)“…Alarmins are considered proximal mediators of the immune response after tissue injury. Understanding their biology could pave the way for development of new…”
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Extracellular vesicle–associated procoagulant activity is highest the first 3 hours after trauma and thereafter declines substantially: A prospective observational pilot study
Published in The journal of trauma and acute care surgery (01-10-2021)“…BACKGROUND Trauma patients have high concentrations of circulating extracellular vesicles (EVs) following injury, but the functional role of EVs in this…”
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HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material
Published in Molecular medicine (Cambridge, Mass.) (31-12-2019)“…HMGB1 is a mediator of systemic inflammation in sepsis and trauma, and a promising biomarker in many diseases. There is currently no standard operating…”
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Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome
Published in Critical care medicine (01-08-2019)“…OBJECTIVES:The causal role of the prototype alarmin high mobility group box 1 protein in systemic inflammation and remote organ injury after trauma and shock…”
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Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study
Published in Molecular medicine (Cambridge, Mass.) (08-04-2021)“…Complement activation is a central mechanism in systemic inflammation and remote organ dysfunction following major trauma. Data on temporal changes of…”
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Pre-hospital critical care management of severe hypoxemia in victims of Covid-19: a case series
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (12-01-2021)“…Despite critical hypoxemia, Covid-19 patients may present without proportional signs of respiratory distress. We report three patients with critical…”
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COVID-19 patients with respiratory failure: what can we learn from aviation medicine?
Published in British journal of anaesthesia : BJA (01-09-2020)Get more information
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Radiation-induced effects on gene expression: An in vivo study on breast cancer
Published in Radiotherapy and oncology (01-08-2006)“…Breast cancer is diagnosed worldwide in approximately one million women annually and radiation therapy is an integral part of treatment. The purpose of this…”
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Covid-19 med stille hypoksemi
Published in Tidsskrift for den Norske Lægeforening (2020)Get full text
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Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome
Published in Critical care medicine (2019)“…Objectives: The causal role of the prototype alarmin high mobility group box 1 protein in systemic inflammation and remote organ injury after trauma and shock…”
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COVID-19 with silent hypoxemia
Published in Tidsskrift for den Norske Lægeforening (05-05-2020)Get full text
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Acute hypoxia in a simulated high-altitude airdrop scenario due to oxygen system failure
Published in Journal of applied physiology (1985) (01-12-2017)“…High-Altitude High Opening (HAHO) is a military operational procedure in which parachute jumps are performed at high altitude requiring supplemental oxygen,…”
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Systemic complement activation 3–6 h after trauma predicts patient outcome
Published in Molecular immunology (01-09-2017)Get full text
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Oculometric Feature Changes During Acute Hypoxia in a Simulated High-Altitude Airdrop Scenario
Published in Aerospace medicine and human performance (01-12-2021)“…Severe acute hypoxia results in a rapid deterioration of cognitive functioning and thus poses a risk for human operations in high altitude environments. This…”
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Tidlig nevrokirurgisk intervensjon ved akutt bakteriell meningitt
Published in Tidsskrift for den Norske Lægeforening (2022)Get full text
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Early neurosurgical intervention in acute bacterial meningitis
Published in Tidsskrift for den Norske Lægeforening (01-03-2022)Get full text
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Prehospital thoracotomy for traumatic cardiac arrest
Published in Tidsskrift for den Norske Lægeforening (01-12-2016)Get full text
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Pre-hospital critical care management of severe hypoxemia in victims of Covid-19 : a case series
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (2021)“…Inneholder sammendrag…”
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